DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment santa-maria and dsb

DIOPT Version :9

Sequence 1:	NP_609121.2	Gene:	santa-maria / 34024	FlyBaseID:	FBgn0025697	Length:	563	Species:	Drosophila melanogaster
Sequence 2:	NP_001097477.1	Gene:	dsb / 38252	FlyBaseID:	FBgn0035290	Length:	615	Species:	Drosophila melanogaster

Alignment Length:	497	Identity:	146/497 - (29%)
Similarity:	237/497 - (47%)	Gaps:	53/497 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 PTQNSAMWGQK----------------------SNRKL---IIGIFGFCLGLFGILCGMFWVDLF 41
            |:|.|...|::                      ||.:|   ||||....||:  ||..|.|:|.|
  Fly    43 PSQGSTATGRRSRPHVTHRGTPLSMLISNGVRISNNRLAVIIIGIITLILGI--ILSSMPWLDYF 105

  Fly    42 DWIMHKEMALAPDTRVYENWKSPPIDLSLDIYLYNWTNPEDFGNLSTKPILEQVGPYRFIERPDK 106
               :.|.:.|..||..|..|:.|.:.....:|:||.|||:.|.. ..||.|::|||:.:.|...|
  Fly   106 ---ILKNLRLWNDTLSYHYWQRPGVIRLTKLYIYNVTNPDGFLR-GEKPHLQEVGPFVYREDMQK 166

  Fly   107 VDIHWHPENASVTYRRRSLFYFDAAGSNGSLDDEITTLNAVALSAAATAKYWPPVKRSLVDVGLK 171
            |::.:|..|.:|:|:.:.:..|....|... |..|||.|...|:..:.:.....:....:.|.:.
  Fly   167 VNVKFHENNYTVSYQHKKILQFVPELSIDK-DTPITTPNIPLLTLTSLSPKLGYLLSKTISVVVT 230

  Fly   172 MYGAEMSVQKSIDELLFTGYNDAMIDVAMAMPIFGDEVKVPFDKFGWFYTRNGSADLTGVFNVFT 236
            ....:..:..:.::|.| ||:||::.:|..   |..:...|.::.|....|||:  ||.|.:|.|
  Fly   231 AAQFKPFINVTAEQLAF-GYDDALVSLAHR---FYPKHMRPMERMGLLLGRNGT--LTEVSSVKT 289

  Fly   237 GADQLAKLGQMHSWNYQENTGFF-DSYCGMTNGSAGE-FQPQHLKPGDSVGLFTPDMCRTIPLDY 299
            |.|.:.:.|.:...|..::...: :..|....||.|. |.|:.|...:.|.::..|:||.|||.|
  Fly   290 GMDSMDQFGYIDQLNGLDHLPHWSEPPCTSIAGSEGSFFPPRELTKSEVVHIYDKDLCRIIPLKY 354

  Fly   300 VETVDIEGLEGYKFSGGPRSVDNGTQYPENLCFCGGQCVP-SGVMNISSCRFGSPVFMSYPHFFN 363
            ||:::.:|:....|.....|..:....|||.|:...:..| .|:.|||.|::|:||::|.||||.
  Fly   355 VESLEKDGIAADLFRLPNNSYGDSAHNPENKCYDTSEYEPIQGLQNISPCQYGAPVYISNPHFFE 419

  Fly   364 ADPYYPDQVEGLSPNQKDHEFYMVVQPSTGIPLEVAARFQVNMLVEPIQGISLYTGIPRIFFPLV 428
            :.|...:.||||.|.::.||.|..:||..|:|||...|.|:|:.|...:.:..........||::
  Fly   420 SHPDLLNSVEGLKPEREKHETYFKIQPKLGVPLEGKVRIQLNLKVTRAKDVYPVRDFRDFVFPVM 484

  Fly   429 WFEQKV-RITPDMADQL--------KVLPI---VMLSGHIFA 458
            |.|:.: .:||.:...:        ..:||   :|:.|..||
  Fly   485 WLEEGISELTPAIKRWIYLGTVIAPSAVPIGSYLMILGGAFA 526

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
santa-maria	NP_609121.2	CD36	23..474	CDD:279474	135/451 (30%)
dsb	NP_001097477.1	CD36	103..532	CDD:279474	129/435 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450711
Domainoid	1	1.000	168	1.000	Domainoid score	I2304
eggNOG	1	0.900	-	-		E1_KOG3776
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	171	1.000	Inparanoid score	I2746
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1106566at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm4750
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11923
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X155
	9	8.900