DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment santa-maria and CG3829

DIOPT Version :9

Sequence 1:	NP_609121.2	Gene:	santa-maria / 34024	FlyBaseID:	FBgn0025697	Length:	563	Species:	Drosophila melanogaster
Sequence 2:	NP_001286874.1	Gene:	CG3829 / 38000	FlyBaseID:	FBgn0035091	Length:	597	Species:	Drosophila melanogaster

Alignment Length:	506	Identity:	127/506 - (25%)
Similarity:	233/506 - (46%)	Gaps:	56/506 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 IIGIFGFCLGLFGILCGMFWVDLFDWIMHKEMALAPDTRVYENW--KSPPIDLSLDIYLYNWTNP 80
            :|.:.||.:        |::.:.::..:.:.:.||.::....:|  ..|..|..|..:::::.|.
  Fly    95 VISVTGFFV--------MWFTEYYNNTILENLILAENSDTANSWLNPDPKYDTLLKAHIFHYPNI 151

  Fly    81 EDF-GNLSTKPILEQVGPYRFIERPDKVDIHWHPENASVTYRRRSLFYFDAAGSNGSLDDEITTL 144
            :|: ...:.|..:..|||..:.|...|.::.:: :|.:|::|.|..:.|....|:....:.:...
  Fly   152 DDYLAGRADKIKVVDVGPLTYQEHTVKDEVSFN-KNFTVSFRDRKSYKFLPEKSSIGEHEVVRVP 215

  Fly   145 NAVALSAAATAKYWPPVKRSLVDVGLKMYGAEMSVQKSIDELLFTGYNDAMIDVAMAMPIFGDEV 209
            |...:|||...|.....:|..|...:|.:...:....::.|.|: ||.|::|    .:...|...
  Fly   216 NVPLISAAGPVKRMKAFERLAVSTWIKQFKEPLFKNLTVSEYLW-GYEDSII----KLKSLGRGR 275

  Fly   210 KVPFDKFGWFYTRNGSADLTGVFNVFTGADQLAKLGQMHSWNYQENTGFFD-SYCGMTNGS-AGE 272
            :    :||...:|||::..:...|  ||.|.:.|...:..:|......::: ..|...:|| ...
  Fly   276 R----RFGLLMSRNGTSVDSVQLN--TGEDDITKFSIITQFNGMPQLDYWEGDECNRIDGSEPSM 334

  Fly   273 FQPQHLKPGDSVGLFTPDMCRTIPLDYVETV----DIEGLEGYKFSGGPRSV-DNGTQYPENLCF 332
            |.|..|:...:|.:|...:||.:||.:.:.|    ||:.|. |:   .|..| .:.::.|.|.|:
  Fly   335 FSPHLLQDRSTVNVFLQVLCRKVPLHFEKEVTIYNDIDVLR-YR---TPMDVFSHPSKNPANQCY 395

  Fly   333 CGGQ--CVPSGVMNISSCRFGSPVFMSYPHFFNADPYYPDQVEGLSPNQKDHEFYMVVQPSTGIP 395
            |...  |:||||:|.:.|...:|:|.|:||||..||......||:.|:...|:.|..:.|..|.|
  Fly   396 CQNTELCLPSGVINATKCYGDAPIFPSFPHFFTGDPVLYQDFEGIEPDAAVHQTYADIHPRFGFP 460

  Fly   396 LEVAARFQVNMLVE--PI---QGISLYTGIPRIFFPLVWFEQKVRITP-DMADQLKVLPIVMLSG 454
            :..|:|.|:|::::  ||   ||..|..   ....||:|.|    ||. |.:::  ||..:.||.
  Fly   461 ISGASRVQINIMLDKTPILRNQGDRLKN---TTILPLMWIE----ITSGDFSEE--VLHTLYLST 516

  Fly   455 HIFAGI--CLIVGITLLCWTPVQILLAS---CRNRRYDLRTKTKTNGQYKS 500
            .....|  .|..|..|:..|...:::|.   ..:||.....::||:.:.::
  Fly   517 FGLNAIQQTLKYGTLLISVTSFSLIVAGVYYLNSRREQQLQESKTSAELEA 567

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
santa-maria	NP_609121.2	CD36	23..474	CDD:279474	121/470 (26%)
CG3829	NP_001286874.1	CD36	91..546	CDD:279474	123/483 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450723
Domainoid	1	1.000	168	1.000	Domainoid score	I2304
eggNOG	1	0.900	-	-		E1_KOG3776
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	171	1.000	Inparanoid score	I2746
Isobase	1	0.950	-	1.030639	Normalized mean entropy	S6187
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1106566at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11923
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X155
	9	8.850