DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment santa-maria and Scarb1

DIOPT Version :9

Sequence 1:	NP_609121.2	Gene:	santa-maria / 34024	FlyBaseID:	FBgn0025697	Length:	563	Species:	Drosophila melanogaster
Sequence 2:	NP_001192012.1	Gene:	Scarb1 / 20778	MGIID:	893578	Length:	520	Species:	Mus musculus

Alignment Length:	515	Identity:	143/515 - (27%)
Similarity:	252/515 - (48%)	Gaps:	45/515 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 MWGQKSNRKLIIGI--FGFCLGLFGILCGMFWVDLFDWIMHKEMALAPDTRVYENWKSPPIDLSL 70
            |.|....|.:.:|:  .|......|::..:....|....:.|.:.:.|.:..:..||..|:...|
Mouse     1 MGGSSRARWVALGLGALGLLFAALGVVMILMVPSLIKQQVLKNVRIDPSSLSFGMWKEIPVPFYL 65

  Fly    71 DIYLYNWTNPEDFGNLSTKPILEQVGPYRFIERPDKVDIHWHPENASVTYRRRSLFYFDAAGSNG 135
            .:|.:...||.:..| ..||::.:.|||.:.|...||:|.:: :|.:|::......:|....|:|
Mouse    66 SVYFFEVVNPNEVLN-GQKPVVRERGPYVYREFRQKVNITFN-DNDTVSFVENRSLHFQPDKSHG 128

  Fly   136 SLDDEITTLNAVALSAAATAKYWPPVKRSLVDVGLKMYGAEMSVQKSIDELLFTGYNDAMID--- 197
            |..|.|...|.:.|..:...:..|...:.::.:.|...|....:.:::.|:|: ||:|..:.
Mouse   129 SESDYIVLPNILVLGGSILMESKPVSLKLMMTLALVTMGQRAFMNRTVGEILW-GYDDPFVHFLN 192

  Fly   198 --VAMAMPIFGDEVKVPFDKFGWFYTRNGSADLTGVFNVFTGADQLAKLGQMHSWNYQENTGFFD 260
              :...:||.|        |||.|...|.|.  :|||.||||....:::..:..||......::.
Mouse   193 TYLPDMLPIKG--------KFGLFVGMNNSN--SGVFTVFTGVQNFSRIHLVDKWNGLSKIDYWH 247

  Fly   261 S-YCGMTNGSAGEFQPQHLKPGDSVGLFTPDMCRTIPLDYVETVDIEGLEGYKFSGGPRSVDNGT 324
            | .|.|.||::|:.....:.|..|:..|:|:.||::.|.|.|:...||:..|:|:.......||:
Mouse   248 SEQCNMINGTSGQMWAPFMTPESSLEFFSPEACRSMKLTYNESRVFEGIPTYRFTAPDTLFANGS 312

  Fly   325 QYPENLCFCGGQCVPSGVMNISSCRFGSPVFMSYPHFFNADPYYPDQVEGLSPNQKDHEFYMVVQ 389
            .||.|..||  .|..||:.|:|:||||:|:|:|:|||:||||...:.|.||:||.|:|..::.:.
Mouse   313 VYPPNEGFC--PCRESGIQNVSTCRFGAPLFLSHPHFYNADPVLSEAVLGLNPNPKEHSLFLDIH 375

  Fly   390 PSTGIPLEVAARFQVNMLVEPIQGISLYTGIPRIFFPLVWFEQKVRI----TPDMADQLKVLPIV 450
            |.||||:..:.:.|:::.::.::||.....|..:..||:||||...:    ......||.::|.|
Mouse   376 PVTGIPMNCSVKMQLSLYIKSVKGIGQTGKIEPVVLPLLWFEQSGAMGGKPLSTFYTQLVLMPQV 440

  Fly   451 M-LSGHIFAGI-CLIVGITLLCWTPVQILLASCRNRRYDLRTKTKTNGQYKSRSQFSSAE 508
            : .:.::..|: .|::.:.::|                .||::....|.:.|.|...||:
Mouse   441 LHYAQYVLLGLGGLLLLVPIIC----------------QLRSQVSRRGGHASDSARVSAD 484

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
santa-maria	NP_609121.2	CD36	23..474	CDD:279474	132/462 (29%)
Scarb1	NP_001192012.1	CD36	26..447	CDD:279474	127/435 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838296
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3776
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45589
OrthoDB	1	1.010	-	-		D1106566at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11923
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X155
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.860