DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5973 and Sec14l2

DIOPT Version :9

Sequence 1:	NP_001162901.1	Gene:	CG5973 / 34023	FlyBaseID:	FBgn0031914	Length:	311	Species:	Drosophila melanogaster
Sequence 2:	NP_653103.1	Gene:	Sec14l2 / 67815	MGIID:	1915065	Length:	403	Species:	Mus musculus

Alignment Length:	272	Identity:	65/272 - (23%)
Similarity:	117/272 - (43%)	Gaps:	54/272 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 KEQAIKELRELIQNEKYLNLPL----DDEYMMMFLRPTHYYPESALKRLKNFYHMKLKYGAACEN 110
            :|:|:.:.||.:|:.    ||.    ||.:::.:||...:..:.:...|:.  |::.:.....:.
Mouse    12 QEEALAKFRENVQDV----LPTLPNPDDYFLLRWLRARSFDLQKSEAMLRK--HVEFRKQKDIDK 70

  Fly   111 IIPSKLRNVFEANI---------------LNLLPQRDQHGRRLLVLEAGK------KWKPSQVPL 154
            ||..:...|.:..:               .:::...|..|   |:..|.|      |.:..::.|
Mouse    71 IISWQPPEVIQQYLSGGRCGYDLDGCPVWYDIIGPLDAKG---LLFSASKQDLLRTKMRDCELLL 132

  Fly   155 VDLFRGIQLTVLGSMVEPYSQICGSVVIIDMEGLPLSHITQFTPSFAAM--LLDYIQECICMRLK 217
            .:..:  |.|.||..:|..:      :|.|.|||.|.|:  :.|:..|.  .|...:|.....||
Mouse   133 QECIQ--QTTKLGKKIETIT------MIYDCEGLGLKHL--WKPAVEAYGEFLTMFEENYPETLK 187

  Fly   218 AVHIVNNSYIFNMLFAVFKPFIREKLRKRIFFHGKDYKS-LISHIEAKALPPKYGGSATWELPHG 281
            .:.:|....:|.:.:.:.|||:.|..|::|...|.::|. |:.||....||.:|||:.|  .|.|
Mouse   188 RLFVVKAPKLFPVAYNLIKPFLSEDTRRKIMVLGANWKEVLLKHISPDQLPVEYGGTMT--DPDG 250

  Fly   282 KVLGEFFECYSK 293
            ..     :|.||
Mouse   251 NP-----KCKSK 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5973	NP_001162901.1	CRAL_TRIO_N	51..96	CDD:215024	12/48 (25%)
CG5973	NP_001162901.1	SEC14	116..272	CDD:238099	42/179 (23%)
Sec14l2	NP_653103.1	CRAL_TRIO_N	13..59	CDD:215024	12/51 (24%)
		SEC14	76..244	CDD:214706	43/180 (24%)
		GOLD_2	300..381	CDD:290608
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1133487at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820