DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5973 and sec14l7

DIOPT Version :9

Sequence 1:	NP_001162901.1	Gene:	CG5973 / 34023	FlyBaseID:	FBgn0031914	Length:	311	Species:	Drosophila melanogaster
Sequence 2:	XP_009303977.1	Gene:	sec14l7 / 566865	ZFINID:	ZDB-GENE-141216-145	Length:	405	Species:	Danio rerio

Alignment Length:	280	Identity:	70/280 - (25%)
Similarity:	123/280 - (43%)	Gaps:	50/280 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 QAIKELRELIQN--EKYLNLPLDDEYMMMFLRP-THYYP--ESALKRLKNF-YHMKLKYGAACEN 110
            :|:.:.||.:::  ::..|  ..|.|::.:||. |...|  |:.|::...| .||||      |.
Zfish    27 EALTQFREKLEDVWDQLSN--QTDHYLLRWLRARTFNVPKAEAMLRKHLEFRRHMKL------ET 83

  Fly   111 II----PSKLRNVFEANILNLLPQRDQHGRRL------------LVLEAGKK-WKPSQVPLVDLF 158
            ||    |.:   |.|..:...:...|:.|..:            |:|.|.|: ...:::...:|.
Zfish    84 IIDDWSPPE---VLERYVAGGMCGYDREGSPIWFDIIGPLDPKGLLLSASKQDCLRTKIRDAELL 145

  Fly   159 R---GIQLTVLGSMVEPYSQICGSVVIIDMEGLPLSHITQFTPSFAAMLLDYIQECICMRLKAVH 220
            |   ..|...||..:|..:      :|.|.|||.:.|:.:........:|...:|.....||.|.
Zfish   146 RRECEKQSKKLGKHIESIT------IIYDCEGLGMKHLWKPAVEMYGEILTMYEENYPESLKKVL 204

  Fly   221 IVNNSYIFNMLFAVFKPFIREKLRKRIFFHGKDYKSLI-SHIEAKALPPKYGGSATWELPHGKVL 284
            ::....:|.:.:.:.|.|:||:.|::|...|.::|.:: ::::|..:|..||||.|  .|.|..|
Zfish   205 LIKAPKLFPIAYNLVKHFLREETRQKIAVLGSNWKDVLKNYVDADQIPAAYGGSLT--DPDGNPL 267

  Fly   285 GEFFECYS----KDYELADS 300
            ......|.    |.|.:.||
Zfish   268 CTTMLRYGGVVPKSYYVRDS 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5973	NP_001162901.1	CRAL_TRIO_N	51..96	CDD:215024	12/48 (25%)
CG5973	NP_001162901.1	SEC14	116..272	CDD:238099	37/172 (22%)
sec14l7	XP_009303977.1	CRAL_TRIO_N	26..72	CDD:215024	12/46 (26%)
		CRAL_TRIO	97..258	CDD:279044	36/166 (22%)
		GOLD_2	317..395	CDD:290608
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1133487at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920