DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5973 and sec14l8

DIOPT Version :9

Sequence 1:	NP_001162901.1	Gene:	CG5973 / 34023	FlyBaseID:	FBgn0031914	Length:	311	Species:	Drosophila melanogaster
Sequence 2:	NP_001093463.1	Gene:	sec14l8 / 558964	ZFINID:	ZDB-GENE-060526-180	Length:	395	Species:	Danio rerio

Alignment Length:	333	Identity:	62/333 - (18%)
Similarity:	122/333 - (36%)	Gaps:	119/333 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 VKE-QAIKELRELIQNEKYLNLP----LDDEYMMMFLRPTHY---YPESALKRLKNF-YHMKL-- 102
            ||: :|:.:.||.:|:.    ||    ..|.:::.:||..::   ..|:.|::...| .|||:
Zfish    10 VKQAEALAQFREKVQDV----LPQCPSQSDHFLLRWLRARNFNLQKSEAMLRKHIEFRKHMKVDT 70

  Fly   103 ------------KY--GAAC----------------------------ENIIPSKLRNVFEANIL 125
                        ||  |..|                            :::|.||:|   :..||
Zfish    71 ITTEWQVPEVIDKYLSGGMCGHDREGSPVWYDVIGPLDPKGLMHSASKQDLIKSKVR---DCEIL 132

  Fly   126 NLLPQRDQHGRRLLVLEAGKKWKPSQVPLVDLFRGIQLTVLGSMVEPYSQICGSVVIIDMEGLPL 190
            .  ...|:...|                            ||..:|..:      ::.|.|||.:
Zfish   133 Q--KDCDRQSER----------------------------LGRNIESIT------MVYDCEGLGM 161

  Fly   191 SHITQFTPSFAAM--LLDYIQECICMRLKAVHIVNNSYIFNMLFAVFKPFIREKLRKRIFFHGKD 253
            .|:  :.|:....  :|...::.....||.:.::....:|.:.:.:.|.|:.|..|:::...|.:
Zfish   162 KHL--YKPAIETYGEVLTMFEDNYPEGLKRLFVIKAPKLFPVAYNLVKHFLSEDTRRKVIVLGSN 224

  Fly   254 YKSLI-SHIEAKALPPKYGGSAT---------------WELPHGKVLGEFFECYSKDYELADSYG 302
            ::.:: .:|:.:.||..|||..|               .|:|....:.:..:.   |||.:.|.|
Zfish   225 WQEVLQKYIDPEELPAYYGGKLTDPDGDPKCRTRITFGSEIPKSYYVRDSIKV---DYEQSVSIG 286

  Fly   303 YTEGYKMK 310
            ....::|:
Zfish   287 RGSSHQME 294

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5973	NP_001162901.1	CRAL_TRIO_N	51..96	CDD:215024	11/52 (21%)
CG5973	NP_001162901.1	SEC14	116..272	CDD:238099	27/158 (17%)
sec14l8	NP_001093463.1	CRAL_TRIO_N	13..59	CDD:215024	11/49 (22%)
		SEC14	78..246	CDD:214706	36/208 (17%)
		GOLD_2	304..382	CDD:290608
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1133487at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820