DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5973 and Sec14l4

DIOPT Version :9

Sequence 1:	NP_001162901.1	Gene:	CG5973 / 34023	FlyBaseID:	FBgn0031914	Length:	311	Species:	Drosophila melanogaster
Sequence 2:	NP_001102560.1	Gene:	Sec14l4 / 498399	RGDID:	1565810	Length:	412	Species:	Rattus norvegicus

Alignment Length:	261	Identity:	57/261 - (21%)
Similarity:	114/261 - (43%)	Gaps:	61/261 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 KEQAIKELRELIQNEKYLNLP-LDDEYMMMFLRPTHYYPESALKRLKNFYHMKLKYGAACENII- 112
            :::|:...||::| :....|| .||.:::.:||..::..:.:...|:.  |::.:.....::|:
  Rat    12 QQEALTRFREILQ-DVLPTLPKADDFFLLRWLRARNFDLKKSEDMLRK--HVEFRNQQDLDHILT 73

  Fly   113 --PSKLRNVFEANIL------------NLLPQRDQHGRRLLVLEAGKKWKPSQVPLVDLFR---- 159
              |.::..::::..|            :|:...|..|   |.:.|.|:         ||.|
  Rat    74 WQPPEVIRLYDSGGLCGYDYEGCPVWFDLIGTLDPKG---LFMSASKQ---------DLIRKRIK 126

  Fly   160 ---------GIQLTVLGSMVEPYSQICGSVVIIDMEGLPLSHITQ-----FTPSFAAMLLDYIQE 210
                     .:|...||..||      ..|::.|||||.|.|:.:     :...||.:..:|.:
  Rat   127 VCEMLLHECELQSQKLGRKVE------RMVMVFDMEGLSLRHLWKPAVEVYQQFFAILEANYPE- 184

  Fly   211 CICMRLKAVHIVNNSYIFNMLFAVFKPFIREKLRKRIFFHGKDYK-SLISHIEAKALPPKYGGSA 274
                .:|.:.::....:|.:.|.:.|.||.|..:|:|...|.::| .|:..:....||.::||:.
  Rat   185 ----TVKNLIVIRAPKLFPVAFNLVKSFIGEVTQKKIVILGGNWKQELLKFMSPDQLPVEFGGTM 245

  Fly   275 T 275
            |
  Rat   246 T 246

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5973	NP_001162901.1	CRAL_TRIO_N	51..96	CDD:215024	11/45 (24%)
CG5973	NP_001162901.1	SEC14	116..272	CDD:238099	40/186 (22%)
Sec14l4	NP_001102560.1	CRAL_TRIO_N	13..59	CDD:215024	11/48 (23%)
		SEC14	76..244	CDD:214706	42/190 (22%)
		GOLD_2	284..379	CDD:404736
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1133487at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910