DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5973 and CG33523

DIOPT Version :9

Sequence 1:	NP_001162901.1	Gene:	CG5973 / 34023	FlyBaseID:	FBgn0031914	Length:	311	Species:	Drosophila melanogaster
Sequence 2:	NP_001261457.1	Gene:	CG33523 / 38668	FlyBaseID:	FBgn0053523	Length:	654	Species:	Drosophila melanogaster

Alignment Length:	275	Identity:	59/275 - (21%)
Similarity:	99/275 - (36%)	Gaps:	74/275 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 VKE---QAIKELRELIQNEKYLNLP---------LDDEYMMMFLRPTHYYPESALKRLKNFYHMK 101
            |||   |.|:|||:.. |.||.:.|         :|.      :|..|.:    |:|....|.:.
  Fly     5 VKETTPQQIEELRDRF-NRKYASSPPAAPFHPTDIDR------IRNDHLW----LQRFLEMYDLD 58

  Fly   102 -------------LKYGAACENIIPSKLRNVF--EANILNLLPQRDQHGRRLLVLEAGKKWKPSQ 151
                         |:......:|..|:|...:  |.::  .:...|..|:.|||...  |.....
  Fly    59 METSFNSLWETCILRQSTGANDIDESELNQEYLKEGSV--FVHNTDVDGKPLLVFRV--KMHSKS 119

  Fly   152 VPLVDLFRGIQLTVLGSMVEPY-SQICGSVVIIDMEGLPLSHITQFTPSFAAMLLDYIQECI--- 212
            ..|.:|.|.:...|..:..|.: :|:   .:..||.|          .|.|:|.|::::..:
  Fly   120 KNLDELIRIVVYWVERTQREQHLTQL---TIFFDMSG----------TSLASMDLEFVKRIVETF 171

  Fly   213 ----CMRLKAVHIVNNSYIFNMLFAVFKPFIREK---LRKRIFFHGKDYKSLISHIEAKALPPKY 270
                ...|..:.:....::.|..|.|.|..:..|   :.|.|  ..||....|:.....|:   :
  Fly   172 KQFYPNSLNYILVYELGWVLNAAFKVIKAVLPPKAVEILKMI--SKKDINQYINKDNCLAI---W 231

  Fly   271 GGSATWE---LPHGK 282
            ||...:|   :|..|
  Fly   232 GGEDNYEFSFVPEAK 246

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5973	NP_001162901.1	CRAL_TRIO_N	51..96	CDD:215024	15/56 (27%)
CG5973	NP_001162901.1	SEC14	116..272	CDD:238099	33/168 (20%)
CG33523	NP_001261457.1	CRAL_TRIO	94..234	CDD:279044	32/161 (20%)
CG33523	NP_001261457.1	Motile_Sperm	293..396	CDD:279029
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900