DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5973 and Sec14l5

DIOPT Version :9

Sequence 1:	NP_001162901.1	Gene:	CG5973 / 34023	FlyBaseID:	FBgn0031914	Length:	311	Species:	Drosophila melanogaster
Sequence 2:	NP_001129182.2	Gene:	Sec14l5 / 287060	RGDID:	1564638	Length:	696	Species:	Rattus norvegicus

Alignment Length:	301	Identity:	59/301 - (19%)
Similarity:	115/301 - (38%)	Gaps:	88/301 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 VKEQAIKELRELIQNEKYLNLPLDDEYMMMFLRPTHYYPESALKRLKNFYHMKLKYGAACENIIP 113
            ::|..:.:||..:|......:| .||:::.|||...::.:.|...|             |::
  Rat   241 MQESCLVQLRRWLQETHKGKIP-KDEHILRFLRARDFHLDKARDML-------------CQS--- 288

  Fly   114 SKLRNVFEANILNLLPQRDQHGRRLLVLEAGKKWKPSQVPLVDLFRG-----------IQLTVLG 167
                          |..|.||...||:    :.|:| ..||.:.:.|           :.:..||
  Rat   289 --------------LSWRKQHQVDLLL----QTWRP-PAPLQEFYAGGWHYQDIDGRPLYILRLG 334

  Fly   168 SM--------------------VEPYSQ-------------ICGSVVIIDMEGLPLSHITQFTPS 199
            .|                    |....|             |.....::|:|||.:.|:  :.|.
  Rat   335 QMDTKGLMKAVGEEALLQHVLSVNEEGQKRCEGNTRQFGRPISSWTCLLDLEGLNMRHL--WRPG 397

  Fly   200 FAAML--LDYIQECICMRLKAVHIVNNSYIFNMLFAVFKPFIREKLRKR-IFFHGKDYK---SLI 258
            ..|:|  ::.:::.....|..:.||....:|.:|:.:..|||.|..|:: :.:.|.:|:   .|:
  Rat   398 VKALLRMIEVVEDNYPETLGRLLIVRAPRVFPVLWTLVSPFINENTRRKFLIYSGSNYQGPGGLV 462

  Fly   259 SHIEAKALPPKYGGSATWELPHGKVLGEFFECYSKDYELAD 299
            .:::...:|...||.:...:|.|.::.:......::.|.||
  Rat   463 DYLDKDVIPDFLGGESVCNVPEGGMVPKSLYLTEEEQEQAD 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5973	NP_001162901.1	CRAL_TRIO_N	51..96	CDD:215024	12/44 (27%)
CG5973	NP_001162901.1	SEC14	116..272	CDD:238099	39/205 (19%)
Sec14l5	NP_001129182.2	PRELI	17..173	CDD:309720
		Amidase	<179..309	CDD:327489	21/103 (20%)
		CRAL_TRIO_N	243..288	CDD:215024	13/58 (22%)
		CRAL_TRIO	314..477	CDD:306996	30/164 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1133487at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820