DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5973 and ctg-2

DIOPT Version :9

Sequence 1:	NP_001162901.1	Gene:	CG5973 / 34023	FlyBaseID:	FBgn0031914	Length:	311	Species:	Drosophila melanogaster
Sequence 2:	NP_001254156.1	Gene:	ctg-2 / 174360	WormBaseID:	WBGene00011756	Length:	408	Species:	Caenorhabditis elegans

Alignment Length:	278	Identity:	58/278 - (20%)
Similarity:	110/278 - (39%)	Gaps:	60/278 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 EVPGVKEQAIKELRELIQNEKYLNLPLDDEYMMM-------------------FLRPTHY--YPE 88
            |:.....:.:.|||:.|..|..|....||::.:|                   .||..|.  ..:
Worm    19 EITESDRKLLDELRKRIHKELELVKEYDDDFSLMRWLIGWDRKIDVVVPKIKFSLRAIHALGLDQ 83

  Fly    89 SALKRLKNFYHMKLKYGAACEN------IIPSKLRNV-FEANILNLLPQRDQHGRRLLVLEAGKK 146
            ..|..|:       |....|::      .:|..|..: .|.|:::|  |...|      |:|.
Worm    84 EDLSTLE-------KVAQKCDDCSVPLRYLPGSLIGLDHENNVVSL--QMIGH------LDAA-- 131

  Fly   147 WKPSQVPLV---DLFR-------GIQLTVLGSMVEPYSQICGSVVIIDMEGLPLSHITQFTPSFA 201
               ..:|..   ||:|       |: :.::..|.:...:..|:.||.|::||.:..|........
Worm   132 ---GLMPATRNSDLYRMRIAESEGV-MQIIRKMEKEQGKPLGTSVIFDLDGLSMVQIDLAALKVV 192

  Fly   202 AMLLDYIQECICMRLKAVHIVNNSYIFNMLFAVFKPFIREKLRKRIFFHGKDYKS-LISHIEAKA 265
            ..:|..:||.....::.:.|||......:|:::..|.:.::.::::...|.|:|. |..:|..:.
Worm   193 TTMLSQLQEMFPDVIRKIFIVNTPTFIQVLWSMISPCLAKQTQQKVKILGNDWKQHLKENIGEEV 257

  Fly   266 LPPKYGGSATWELPHGKV 283
            |..::||:...|..:|.|
Worm   258 LFERWGGTRKAETEYGNV 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5973	NP_001162901.1	CRAL_TRIO_N	51..96	CDD:215024	14/65 (22%)
CG5973	NP_001162901.1	SEC14	116..272	CDD:238099	35/167 (21%)
ctg-2	NP_001254156.1	SEC14	98..267	CDD:214706	38/182 (21%)
ctg-2	NP_001254156.1	EMP24_GP25L	331..>405	CDD:279450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1133487at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920