DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5973 and Sec14l4

DIOPT Version :9

Sequence 1:	NP_001162901.1	Gene:	CG5973 / 34023	FlyBaseID:	FBgn0031914	Length:	311	Species:	Drosophila melanogaster
Sequence 2:	NP_666125.1	Gene:	Sec14l4 / 103655	MGIID:	2144095	Length:	403	Species:	Mus musculus

Alignment Length:	258	Identity:	54/258 - (20%)
Similarity:	107/258 - (41%)	Gaps:	55/258 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 KEQAIKELRELIQNEKYLNLP-LDDEYMMMFLRPTHYYPESALKRLKNFYHMKLKYGAACENIIP 113
            :::|:...||.:| :....|| .||.:::.:||..::..:.:...|:.  |::.:.....:.|:.
Mouse    12 QQEALARFRETLQ-DLLPTLPKADDYFLLRWLRARNFDLKKSEDMLRK--HVEFRNQQNLDQILT 73

  Fly   114 SKLRNVFEANILNLLPQRDQHG------------RRLLVLEAGKKWKPSQVPLVDLFR------- 159
            .:...|.:......|...|..|            .:.|.:.|.|:         |:.|
Mouse    74 WQAPEVIQLYDSGGLSGYDYEGCPVWFDIIGTMDPKGLFMSASKQ---------DMIRKRIKVCE 129

  Fly   160 ------GIQLTVLGSMVEPYSQICGSVVIIDMEGLPLSHITQ-----FTPSFAAMLLDYIQECIC 213
                  .:|...||..:|      ..|::.|||||.|.|:.:     :...||.:..:|.:
Mouse   130 MLLHECELQSQKLGRKIE------RMVMVFDMEGLSLRHLWKPAVEVYQQFFAILEANYPE---- 184

  Fly   214 MRLKAVHIVNNSYIFNMLFAVFKPFIREKLRKRIFFHGKDYK-SLISHIEAKALPPKYGGSAT 275
             .:|.:.|:....:|.:.|.:.|.|:.|:.:|:|...|.::| .|:..:....||.::||:.|
Mouse   185 -TVKNLIIIRAPKLFPVAFNLVKSFMGEETQKKIVILGGNWKQELVKFVSPDQLPVEFGGTMT 246

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5973	NP_001162901.1	CRAL_TRIO_N	51..96	CDD:215024	11/45 (24%)
CG5973	NP_001162901.1	SEC14	116..272	CDD:238099	38/186 (20%)
Sec14l4	NP_666125.1	CRAL_TRIO_N	13..59	CDD:215024	11/48 (23%)
		SEC14	77..244	CDD:214706	39/186 (21%)
		GOLD_2	284..379	CDD:290608
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1133487at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820