DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5973 and si:dkey-237i9.1

DIOPT Version :9

Sequence 1:	NP_001162901.1	Gene:	CG5973 / 34023	FlyBaseID:	FBgn0031914	Length:	311	Species:	Drosophila melanogaster
Sequence 2:	XP_021332743.1	Gene:	si:dkey-237i9.1 / 100535835	ZFINID:	ZDB-GENE-060503-441	Length:	719	Species:	Danio rerio

Alignment Length:	331	Identity:	73/331 - (22%)
Similarity:	126/331 - (38%)	Gaps:	88/331 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 PEWAL------KKAQDELR-----------EVPGV---KEQAIKELRELIQ--NEKYLNLP---L 71
            |.|::      |..:..:|           |||.|   ..|..||....:.  |:..:..|   |
Zfish   179 PRWSVCPSSPTKSMKPVVRPELHLIPTVTIEVPPVCMNDTQVCKETSNPLSSLNDTLIASPDDKL 243

  Fly    72 DDEYMMMFLRPTHYYPESALKRLKNFYHMKLKYGAACENIIPSKLR----NVFEAN--ILNLLPQ 130
            |.:|:..:|.......||.|.||:::.....|.....:..|...||    |:.:|.  :...|..
Zfish   244 DADYIKRYLGDLTPLQESCLIRLRHWLQETHKGKIPKDEHILRFLRARDFNIDKAREILCQSLTW 308

  Fly   131 RDQHGRRLLVLEAGKKWKPSQVPLVDLFRG-----------IQLTVLGSM--------------- 169
            |.||....|:    ..|...|| |.|.:.|           :.:..||.|
Zfish   309 RKQHQVDYLL----DTWSSPQV-LHDFYTGGWHHHDNDGRPLYILRLGHMDTKGLVRALGEESLL 368

  Fly   170 -------------VEPYSQICGSVV-----IIDMEGLPLSHITQFTPSFAAML--LDYIQECICM 214
                         .|..:::.|..:     ::|:|||.:.|:  :.|:..|:|  ::.::.....
Zfish   369 RHVLSINEEGLRRCEENTKVFGRPISCWTCLVDLEGLNMRHL--WRPAVKALLRIIEVVEANYPE 431

  Fly   215 RLKAVHIVNNSYIFNMLFAVFKPFIREKLRKR-IFFHGKDYK---SLISHIEAKALPPKYGGSAT 275
            .|..:.|:....:|.:|:.:..|||.|..||: :.:.|.||:   .|:.:|:.:.:|...||...
Zfish   432 TLGRLLILRAPRVFPVLWTLVSPFIDENTRKKFLIYAGNDYQGSGGLVDYIDKEVIPDFLGGECM 496

  Fly   276 WELPHG 281
            .|:|.|
Zfish   497 CEVPEG 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5973	NP_001162901.1	CRAL_TRIO_N	51..96	CDD:215024	14/49 (29%)
CG5973	NP_001162901.1	SEC14	116..272	CDD:238099	44/211 (21%)
si:dkey-237i9.1	XP_021332743.1	PRELI	17..173	CDD:309720
		CRAL_TRIO_N	260..305	CDD:215024	11/44 (25%)
		CRAL_TRIO	331..494	CDD:306996	31/164 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1133487at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920