DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG5958 and SEC14L1

DIOPT Version :9

Sequence 1:NP_609119.2 Gene:CG5958 / 34022 FlyBaseID:FBgn0031913 Length:294 Species:Drosophila melanogaster
Sequence 2:NP_001034662.3 Gene:SEC14L1 / 6397 HGNCID:10698 Length:719 Species:Homo sapiens


Alignment Length:291 Identity:64/291 - (21%)
Similarity:131/291 - (45%) Gaps:48/291 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly    30 LRETEEVKAEAIIKLRELLKATPELNYKDDDAFLTVFLRACHFYPEGALEKMKTTASFRKEYASL 94
            |.:...::...:|:||:.|:.|.:.....|:..|. ||||..|..:.|.|.|..:.::||::.  
Human   248 LGDLTPLQESCLIRLRQWLQETHKGKIPKDEHILR-FLRARDFNIDKAREIMCQSLTWRKQHQ-- 309

  Fly    95 VRGLLVEQVKEKFVKGSVINVL-----KNCDQKGRRVLIVNCGKLWDPSDIT----SDEMFRMLY 150
                 |:.:.|.:....|:...     .:.|:.||.:.::..|:: |...:.    .:.:.|.:.
Human   310 -----VDYILETWTPPQVLQDYYAGGWHHHDKDGRPLYVLRLGQM-DTKGLVRALGEEALLRYVL 368

  Fly   151 MVHLAA--QLEEETQVRG-----VVCIMDFEGLSMKQ-----VKALSPSFSKRLLTFIQEAMPLR 203
            .::...  :.||.|:|.|     ..|::|.|||:|:.     ||||     .|::..::...|..
Human   369 SINEEGLRRCEENTKVFGRPISSWTCLVDLEGLNMRHLWRPGVKAL-----LRIIEVVEANYPET 428

  Fly   204 MKEVHFVKQPFIFNMVWSLFKPFVKQKLNNRMHF---HGSDMK---SLQKFLDPSVLPANYKG-T 261
            :..:..::.|.:|.::|:|..||:..  |.|..|   .|:|.:   .|..::|..::|....| .
Human   429 LGRLLILRAPRVFPVLWTLVSPFIDD--NTRRKFLIYAGNDYQGPGGLLDYIDKEIIPDFLSGEC 491

  Fly   262 LPAIDYGGVE----WFPALEQQAQYVEEWSQ 288
            :..:..||:.    :..|.|.:.:.::.|::
Human   492 MCEVPEGGLVPKSLYRTAEELENEDLKLWTE 522

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5958NP_609119.2 CRAL_TRIO_N 38..82 CDD:215024 14/43 (33%)
CRAL_TRIO 111..261 CDD:279044 39/177 (22%)
SEC14L1NP_001034662.3 PRELI 17..173 CDD:368069
CRAL_TRIO_N 256..301 CDD:215024 15/45 (33%)
CRAL_TRIO 326..490 CDD:366224 37/171 (22%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1471
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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