DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5958 and clvs2

DIOPT Version :9

Sequence 1:	NP_609119.2	Gene:	CG5958 / 34022	FlyBaseID:	FBgn0031913	Length:	294	Species:	Drosophila melanogaster
Sequence 2:	NP_001020716.1	Gene:	clvs2 / 566769	ZFINID:	ZDB-GENE-041014-313	Length:	329	Species:	Danio rerio

Alignment Length:	278	Identity:	88/278 - (31%)
Similarity:	151/278 - (54%)	Gaps:	11/278 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 HLRLGYLKPETVEIARVELRETEEVKAEAIIKLRELLKATPELNY-KDDDAFLTVFLRACHFYPE 75
            ||:.| |.|||:|.|:|||:|..:...:.|.::|:::...|::.: :.||||:..||||..|...
Zfish     3 HLQAG-LSPETLEKAKVELKENPDTLHQDIQEVRDMIITRPDIGFLRTDDAFILRFLRARKFNHF 66

  Fly    76 GALEKMKTTASFRKEYASLVRGLLVEQ--VKEKFVKGSVINVLKNCDQKGRRVLIVNCGKLWDPS 138
            .|...:.....:|::...:.:.|....  :|:. :|.....||.|.|:.||::|::.... ||.|
Zfish    67 EAFRLLAQYFEYRQQNLDMFKNLKATDPGIKQA-LKDGFPGVLSNLDRYGRKILVLFAAN-WDQS 129

  Fly   139 DITSDEMFRMLYMVHLAAQLEE-ETQVRGVVCIMDFEGLSMKQVKALSPSFSKRLLTFIQEAMPL 202
            ..|..::.|.: ::.|.|.:|: |.||.|.|.|:|:...:.||...|:||..:..:..:|::.|.
Zfish   130 RYTFVDILRAI-LLSLEAMIEDPELQVNGFVLIIDWSNFTFKQASKLTPSMLRLAIEGLQDSFPA 193

  Fly   203 RMKEVHFVKQPFIFNMVWSLFKPFVKQKLNNRMHFHGSDMKSLQKFLDPSVLPANYKGTLPAIDY 267
            |...:|||.||:..:.::::.:||:|.|...|:..||:::.||.:.:.|.:||:...|.||..|.
Zfish   194 RFGGIHFVNQPWYIHALYTVIRPFLKDKTRKRIFMHGNNLNSLHQLILPEILPSELGGMLPPYDM 258

  Fly   268 GGVEWFPALEQQAQYVEE 285
            |  .|...|...| |.||
Zfish   259 G--TWARTLLDHA-YDEE 273

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5958	NP_609119.2	CRAL_TRIO_N	38..82	CDD:215024	13/44 (30%)
CG5958	NP_609119.2	CRAL_TRIO	111..261	CDD:279044	47/150 (31%)
clvs2	NP_001020716.1	CRAL_TRIO_N	29..75	CDD:215024	13/45 (29%)
		SEC14	106..251	CDD:238099	47/146 (32%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	293..329
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG59833
OrthoDB	1	1.010	-	-		D559280at33208
OrthoFinder	1	1.000	-	-		FOG0000233
OrthoInspector	1	1.000	-	-		mtm8432
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X106
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.830