DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5958 and sec14l5

DIOPT Version :9

Sequence 1:	NP_609119.2	Gene:	CG5958 / 34022	FlyBaseID:	FBgn0031913	Length:	294	Species:	Drosophila melanogaster
Sequence 2:	XP_031749906.1	Gene:	sec14l5 / 493292	XenbaseID:	XB-GENE-953433	Length:	793	Species:	Xenopus tropicalis

Alignment Length:	279	Identity:	66/279 - (23%)
Similarity:	121/279 - (43%)	Gaps:	58/279 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 PETVEIARVELRETEEVKAEA-----------------IIKLRELLKATPELNYKDDDAFLTVFL 67
            |.:...|..||..|.:.|.:|                 :|:||:.|:.|.:.....|:..|. ||
Frog   221 PSSPTAATHELSSTPDDKLDADYIKRYLGDLTPLQESCLIRLRQWLQETHKGKIPKDEHILR-FL 284

  Fly    68 RACHFYPEGALEKMKTTASFRKEYASLVRGLL----VEQVKEKFVKGSVINVLKNCDQKGRRVLI 128
            ||..|..:.|.|.:..:.::||::.  |..||    ..||...:..|.    ..:.|:.||.:.:
Frog   285 RARDFNIDKAREILCQSLTWRKQHH--VDYLLSTWDPPQVLHDYYAGG----WHHHDRDGRPLYV 343

  Fly   129 VNCGKLWDPSDIT----SDEMFRMLYMVHLAA--QLEEETQVRG-----VVCIMDFEGLSMKQ-- 180
            :..|:: |...:.    .:.:.|.:..::...  :.||.|.:.|     ..|::|.|||:|:.
Frog   344 LRLGQM-DTKGLVRALGEESLLRHVLSINEEGLRRCEENTNIFGRPISSWTCLVDLEGLNMRHLW 407

  Fly   181 ---VKALSPSFSKRLLTFIQEAMPLRMKEVHFVKQPFIFNMVWSLFKPFVKQKLNNRMHF---HG 239
               ||||     .|::..::...|..:..:..::.|.:|.::|:|..||:.:  |.|..|   .|
Frog   408 RPGVKAL-----LRIIEVVEANYPETLGRLLILRAPRVFPVLWTLVSPFIDE--NTRKKFLIYAG 465

  Fly   240 SDMK---SLQKFLDPSVLP 255
            :|.:   .|..::|..|:|
Frog   466 NDYQGPGGLIDYIDKEVIP 484

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5958	NP_609119.2	CRAL_TRIO_N	38..82	CDD:215024	15/60 (25%)
CG5958	NP_609119.2	CRAL_TRIO	111..261	CDD:279044	37/167 (22%)
sec14l5	XP_031749906.1	PRELI	17..173	CDD:398400
		CRAL_TRIO_N	256..301	CDD:215024	14/45 (31%)
		CRAL_TRIO	326..490	CDD:395525	38/171 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910