DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5958 and Clvs1

DIOPT Version :9

Sequence 1:	NP_609119.2	Gene:	CG5958 / 34022	FlyBaseID:	FBgn0031913	Length:	294	Species:	Drosophila melanogaster
Sequence 2:	NP_001102439.1	Gene:	Clvs1 / 366311	RGDID:	1564200	Length:	354	Species:	Rattus norvegicus

Alignment Length:	291	Identity:	90/291 - (30%)
Similarity:	153/291 - (52%)	Gaps:	23/291 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 DIAEEAFHLRLGYLKPETVEIARVELRETEEVKAEAIIKLRELLKATPELNY-KDDDAFLTVFLR 68
            |:|:.. ||:.| |.|:|:|.||:||.|..:|..:.|.::|:::...|::.: :.||||:..|||
  Rat    19 DLAKMT-HLQAG-LSPDTIEKARLELNENPDVLHQDIQQVRDMIITRPDIGFLRTDDAFILRFLR 81

  Fly    69 ACHFYPEGALEKMKTTASFRKEYASLVRGLLVEQ--VKEKFVKGSVINVLKNCDQKGRRVLIVNC 131
            |..|:...|...:.....:|:....:.:....:.  :|...:.| ...||:|.|..||::|::..
  Rat    82 ARKFHQADAFRLLAQYFQYRQLNLDMFKNFKADDPGIKRALIDG-FPGVLENRDHYGRKILLLFA 145

  Fly   132 GKLWDPSDITSDEMFRMLYMVHLAAQLEE-ETQVRGVVCIMDFEGLSMKQVKALSPSFSKRLLTF 195
            .. ||.|..:..::.|.: ::.|...:|: |.|:.|.:.|:|:...|.||...|:||..|..:..
  Rat   146 AN-WDQSRNSFTDILRAI-LLSLEVLIEDPELQINGFILIIDWSNFSFKQASKLTPSILKLAIEG 208

  Fly   196 IQEAMPLRMKEVHFVKQPFIFNMVWSLFKPFVKQKLNNRMHFHGSDMKSLQKFLDPSVLPANYKG 260
            :|::.|.|...||||.||:..:.:::|.|||:|.|...|:..||:::.||.:.:.|..||:.:.|
  Rat   209 LQDSFPARFGGVHFVNQPWYIHALYTLIKPFLKDKTRKRIFLHGNNLNSLHQLIHPEFLPSEFGG 273

  Fly   261 TLPAIDYGGVEWFPALEQQAQYVEEWSQLGP 291
            |||..|.|  .|...|            |||
  Rat   274 TLPPYDMG--TWARTL------------LGP 290

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5958	NP_609119.2	CRAL_TRIO_N	38..82	CDD:215024	13/44 (30%)
CG5958	NP_609119.2	CRAL_TRIO	111..261	CDD:279044	48/150 (32%)
Clvs1	NP_001102439.1	CRAL_TRIO_N	51..97	CDD:215024	13/45 (29%)
		CRAL_TRIO	125..274	CDD:395525	49/151 (32%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	317..354
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG59833
OrthoDB	1	1.010	-	-		D559280at33208
OrthoFinder	1	1.000	-	-		FOG0000233
OrthoInspector	1	1.000	-	-		mtm9153
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X106
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.930