DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5958 and Sec14l5

DIOPT Version :9

Sequence 1:	NP_609119.2	Gene:	CG5958 / 34022	FlyBaseID:	FBgn0031913	Length:	294	Species:	Drosophila melanogaster
Sequence 2:	NP_001129182.2	Gene:	Sec14l5 / 287060	RGDID:	1564638	Length:	696	Species:	Rattus norvegicus

Alignment Length:	309	Identity:	70/309 - (22%)
Similarity:	133/309 - (43%)	Gaps:	68/309 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 LGYLKPETVEIARVELRETEEVKAEAIIKLRELLKATPELNYKDDDAFLTVFLRACHFYPEGALE 79
            ||:|.|               ::...:::||..|:.|.:.....|:..|. ||||..|:.:.|.:
  Rat   235 LGHLSP---------------MQESCLVQLRRWLQETHKGKIPKDEHILR-FLRARDFHLDKARD 283

  Fly    80 KMKTTASFRKEYASLVRGLLVEQVK-----EKFVKGSVINVLKNCDQKGRRVLIVNCGKLWDPSD 139
            .:..:.|:||::..   .||::..:     ::|..|.    ....|..||.:.|:..|:: |...
  Rat   284 MLCQSLSWRKQHQV---DLLLQTWRPPAPLQEFYAGG----WHYQDIDGRPLYILRLGQM-DTKG 340

  Fly   140 ----ITSDEMFRMLYMVHLAAQLEEETQVR-------GVVCIMDFEGLSMKQ-----VKALSPSF 188
                :..:.:.:.:..|:...|...|...|       ...|::|.|||:|:.     ||||
  Rat   341 LMKAVGEEALLQHVLSVNEEGQKRCEGNTRQFGRPISSWTCLLDLEGLNMRHLWRPGVKAL---- 401

  Fly   189 SKRLLTFIQEAMPLRMKEVHFVKQPFIFNMVWSLFKPFVKQKLNNRMHF---HGSDMK---SLQK 247
             .|::..:::..|..:..:..|:.|.:|.::|:|..||:.:  |.|..|   .||:.:   .|..
  Rat   402 -LRMIEVVEDNYPETLGRLLIVRAPRVFPVLWTLVSPFINE--NTRRKFLIYSGSNYQGPGGLVD 463

  Fly   248 FLDPSVLPANYKG-TLPAIDYGGVEWFPAL-------EQQAQYVEEWSQ 288
            :||..|:|....| ::..:..||:  .|..       ::||..:.:||:
  Rat   464 YLDKDVIPDFLGGESVCNVPEGGM--VPKSLYLTEEEQEQADQLRQWSE 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5958	NP_609119.2	CRAL_TRIO_N	38..82	CDD:215024	12/43 (28%)
CG5958	NP_609119.2	CRAL_TRIO	111..261	CDD:279044	40/172 (23%)
Sec14l5	NP_001129182.2	PRELI	17..173	CDD:309720
		Amidase	<179..309	CDD:327489	21/92 (23%)
		CRAL_TRIO_N	243..288	CDD:215024	12/45 (27%)
		CRAL_TRIO	314..477	CDD:306996	40/174 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810