DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5958 and Ttpa

DIOPT Version :9

Sequence 1:	NP_609119.2	Gene:	CG5958 / 34022	FlyBaseID:	FBgn0031913	Length:	294	Species:	Drosophila melanogaster
Sequence 2:	NP_037180.1	Gene:	Ttpa / 25571	RGDID:	3915	Length:	278	Species:	Rattus norvegicus

Alignment Length:	259	Identity:	80/259 - (30%)
Similarity:	125/259 - (48%)	Gaps:	22/259 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 AIIKLRELLKATPELNYKDDDAFLTVFLRACHFYPEGALEKMKTTASFRKEYASL--------VR 96
            |.::.|...:..||......||||..||||..|..:.|...||....:|.|...|        :.
  Rat    29 AELRRRAQEEGVPETPQPLTDAFLLRFLRARDFDLDLAWRLMKNYYKWRAECPELSADLHPRSIL 93

  Fly    97 GLLVEQVKEKFVKGSVINVLKNCDQKGRRVLIVNCGKLWDPSDITSDEMFRMLYMVHLAAQLEEE 161
            |||         |.....||::.|..|.||||... ..|||...|:.::||:..:.......|.|
  Rat    94 GLL---------KAGYHGVLRSRDPTGSRVLIYRI-SYWDPKVFTAYDVFRVSLITSELIVQEVE 148

  Fly   162 TQVRGVVCIMDFEGLSMKQVKALSPSFSKRLLTFIQEAMPLRMKEVHFVKQPFIFNMVWSLFKPF 226
            ||..||..|.|.||..:.....::||.:|::...:.::.||:::.:|.:.:|.||:.|:|:.|||
  Rat   149 TQRNGVKAIFDLEGWQISHAFQITPSVAKKIAAVVTDSFPLKVRGIHLINEPVIFHAVFSMIKPF 213

  Fly   227 VKQKLNNRMHFHGSDMKS--LQKFLDPSVLPANYKGTLPAIDYGGVEWFPALEQQAQYVEEWSQ 288
            :.:|:..|:|.||::.||  ||.|  |.:||..|.|...:::....||...:.:...|:...|:
  Rat   214 LTEKIKGRIHLHGNNYKSSLLQHF--PDILPLEYGGNESSMEDICQEWTNFIMKSEDYLSSISE 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5958	NP_609119.2	CRAL_TRIO_N	38..82	CDD:215024	14/41 (34%)
CG5958	NP_609119.2	CRAL_TRIO	111..261	CDD:279044	52/151 (34%)
Ttpa	NP_037180.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..22
		CRAL_TRIO_N	25..73	CDD:215024	16/43 (37%)
		CRAL_TRIO	99..248	CDD:395525	52/151 (34%)
		Phosphatidylinositol 3,4-bisphosphate binding. /evidence=ECO:0000250\|UniProtKB:Q8BWP5	190..192		0/1 (0%)
		Phosphatidylinositol 4,5-bisphosphate binding. /evidence=ECO:0000250\|UniProtKB:Q8BWP5	208..211		1/2 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1053004at2759
OrthoFinder	1	1.000	-	-		FOG0000233
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10174
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X106
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.920