DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5958 and Clvs2

DIOPT Version :9

Sequence 1:	NP_609119.2	Gene:	CG5958 / 34022	FlyBaseID:	FBgn0031913	Length:	294	Species:	Drosophila melanogaster
Sequence 2:	NP_780657.1	Gene:	Clvs2 / 215890	MGIID:	2443223	Length:	327	Species:	Mus musculus

Alignment Length:	265	Identity:	80/265 - (30%)
Similarity:	146/265 - (55%)	Gaps:	16/265 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 HLRLGYLKPETVEIARVELRETEEVKAEAIIKLRELLKATPELNY-KDDDAFLTVFLRACHFYPE 75
            ||:.| |.|||:|.||:||.|..:...:.|.::|:::...|::.: :.||||:..||||..|:..
Mouse     3 HLQAG-LSPETLEKARLELNENPDTLHQDIQEVRDMVITRPDIGFLRTDDAFILRFLRARKFHHF 66

  Fly    76 GALEKMKTTASFRKEYASLVRGL------LVEQVKEKFVKGSVINVLKNCDQKGRRVLIVNCGKL 134
            .|...:.....:|::...:.:..      :.:.:|:.|..|     |.|.|..||::|::....
Mouse    67 EAFRLLAQYFEYRQQNLDMFKSFKATDPGIKQALKDGFPGG-----LANLDHYGRKILVLFAAN- 125

  Fly   135 WDPSDITSDEMFRMLYMVHLAAQLEE-ETQVRGVVCIMDFEGLSMKQVKALSPSFSKRLLTFIQE 198
            ||.|..|..::.|.: ::.|.|.:|: |.||.|.|.|:|:...:.||...|:|:..:..:..:|:
Mouse   126 WDQSRYTLVDILRAI-LLSLEAMIEDPELQVNGFVLIIDWSNFTFKQASKLTPNMLRLAIEGLQD 189

  Fly   199 AMPLRMKEVHFVKQPFIFNMVWSLFKPFVKQKLNNRMHFHGSDMKSLQKFLDPSVLPANYKGTLP 263
            :.|.|...:|||.||:..:.::::.:||:|:|...|:..||:::.||.:.:.|.:||:.:.|.||
Mouse   190 SFPARFGGIHFVNQPWYIHALYTVIRPFLKEKTRKRIFLHGNNLNSLHQLIHPEILPSEFGGMLP 254

  Fly   264 AIDYG 268
            ..|.|
Mouse   255 PYDMG 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5958	NP_609119.2	CRAL_TRIO_N	38..82	CDD:215024	13/44 (30%)
CG5958	NP_609119.2	CRAL_TRIO	111..261	CDD:279044	45/150 (30%)
Clvs2	NP_780657.1	CRAL_TRIO_N	29..75	CDD:215024	13/45 (29%)
		SEC14	106..251	CDD:238099	46/151 (30%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	289..327
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG59833
OrthoDB	1	1.010	-	-		D559280at33208
OrthoFinder	1	1.000	-	-		FOG0000233
OrthoInspector	1	1.000	-	-		mtm8767
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X106
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.830