Protein Alignment CG5958 and MOSPD2

DIOPT Version :10

• Sequence 1: NP_609119.2
• Gene: CG5958 / 34022
• FlyBaseID: FBgn0031913
• Length: 294
• Species: Drosophila melanogaster
• Sequence 2: NP_689794.1
• Gene: MOSPD2 / 158747
• HGNCID: 28381
• Length: 518
• Species: Homo sapiens
• Alignment Length: 257
• Identity: 42/257 - (16%)
• Similarity: 93/257 - (36%)
• Gaps: 59/257 - (22%)

  Fly    37 KAEAIIKLRELLKATPELNYKD------------DDAFLTVFLRACHFYPEGALEKMKTTASFRK 89
            ||:.|.:.|...:|....:..|            ||.::..:|...|...:..|:.:..:..:||
Human     9 KAKLISETRRRFEAEYVTDKSDKYDARDVERLQQDDNWVESYLSWRHNIVDETLKMLDESFQWRK 73

  Fly    90 EYASLVRGLLVEQVKEKFVKGSVINV----LKNCDQKGRRVLIVNCGKLWDPSDITSDEMFRMLY 150
            |       :.|..:.|..:...::.:    |...|::|.::       .|          .|:.|
Human    74 E-------ISVNDLNESSIPRWLLEIGVIYLHGYDKEGNKL-------FW----------IRVKY 114

  Fly   151 MVH-----------LAAQLE---EETQVRGVVCIMDFEGLSMKQVKALSPSFSKRLLTFIQEAMP 201
            .|.           :|..||   :....:.|..:.|   ||...:.::...|.:.::...:...|
Human   115 HVKDQKTILDKKKLIAFWLERYAKRENGKPVTVMFD---LSETGINSIDMDFVRFIINCFKVYYP 176

  Fly   202 LRMKEVHFVKQPFIFNMVWSLFKPFVKQKLNNRMHFHGSDMKSLQKFLDPSVLPANYKGTLP 263
            ..:.::.....|::.|..:.:.|.::..:..:.:.|  :....:|.::....||.:..||.|
Human   177 KYLSKIVIFDMPWLMNAAFKIVKTWLGPEAVSLLKF--TSKNEVQDYVSVEYLPPHMGGTDP 236

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5958	NP_609119.2	CRAL_TRIO_N	38..82	CDD:215024	10/55 (18%)
		CRAL_TRIO	111..260	CDD:459890	23/166 (14%)
MOSPD2	NP_689794.1	SEC14	93..234	CDD:469559	23/162 (14%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	252..308
		Motile_Sperm	327..431	CDD:459882
		Required for FFAT motif binding and phosphorylated FFAT motif binding. /evidence=ECO:0000269|PubMed:33124732, ECO:0007744|PDB:6TQS, ECO:0007744|PDB:6TQU	365..366