DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5958 and Sec14l4

DIOPT Version :9

Sequence 1:	NP_609119.2	Gene:	CG5958 / 34022	FlyBaseID:	FBgn0031913	Length:	294	Species:	Drosophila melanogaster
Sequence 2:	NP_666125.1	Gene:	Sec14l4 / 103655	MGIID:	2144095	Length:	403	Species:	Mus musculus

Alignment Length:	299	Identity:	72/299 - (24%)
Similarity:	129/299 - (43%)	Gaps:	54/299 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 RLGYLKPETVEIARVELRETEEVKAEAIIKLRELLKATPELNYKDDDAFLTVFLRACHFYPEGAL 78
            ::|.|.|:..| |....|||          |::||...|    |.||.||..:|||.:|..:.:.
Mouse     4 QVGDLSPQQQE-ALARFRET----------LQDLLPTLP----KADDYFLLRWLRARNFDLKKSE 53

  Fly    79 EKMKTTASFRKEYASLVRGLLVEQVKEKFVKGSVINV-----LKNCDQKGRRVLIVNCGKLWDPS 138
            :.::....||.:  ..:..:|..|..|      ||.:     |...|.:|..|.....|.: ||.
Mouse    54 DMLRKHVEFRNQ--QNLDQILTWQAPE------VIQLYDSGGLSGYDYEGCPVWFDIIGTM-DPK 109

  Fly   139 DI----TSDEMFRMLYMV--HLAAQLEEETQVRG-----VVCIMDFEGLSMKQVKALSPSFSKRL 192
            .:    :..:|.|....|  .|..:.|.::|..|     :|.:.|.||||::.:...:....::.
Mouse   110 GLFMSASKQDMIRKRIKVCEMLLHECELQSQKLGRKIERMVMVFDMEGLSLRHLWKPAVEVYQQF 174

  Fly   193 LTFIQEAMPLRMKEVHFVKQPFIFNMVWSLFKPFVKQKLNNRMHFHGSDMK-SLQKFLDPSVLPA 256
            ...::...|..:|.:..::.|.:|.:.::|.|.|:.::...::...|.:.| .|.||:.|..||.
Mouse   175 FAILEANYPETVKNLIIIRAPKLFPVAFNLVKSFMGEETQKKIVILGGNWKQELVKFVSPDQLPV 239

  Fly   257 NYKGT----------LPAIDYGG---VEWFPALEQQAQY 282
            .:.||          |..|:|||   ..::.:.:::.||
Mouse   240 EFGGTMTDPDGNPKCLTKINYGGEVPKRYYLSNQERPQY 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5958	NP_609119.2	CRAL_TRIO_N	38..82	CDD:215024	13/43 (30%)
CG5958	NP_609119.2	CRAL_TRIO	111..261	CDD:279044	37/166 (22%)
Sec14l4	NP_666125.1	CRAL_TRIO_N	13..59	CDD:215024	18/60 (30%)
		SEC14	77..244	CDD:214706	38/173 (22%)
		GOLD_2	284..379	CDD:290608
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810