Protein Alignment muc and PDX1

DIOPT Version :9

• Sequence 1: NP_001260196.1
• Gene: muc / 34021
• FlyBaseID: FBgn0283658
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: NP_011709.1
• Gene: PDX1 / 853107
• SGDID: S000003425
• Length: 410
• Species: Saccharomyces cerevisiae
• Alignment Length: 478
• Identity: 104/478 - (21%)
• Similarity: 190/478 - (39%)
• Gaps: 103/478 - (21%)

  Fly    55 SKLNTSQSPVTW--SYNFARAYANLPEHIRVPLPALSPTMERGSIVSWEKKEGDKLNEGDLLCEI 117
            ||::|.:|...:  ..|: .|.|.|.......:||:|||||:|.||||:.|.|:..:.||::.|:
Yeast     6 SKVSTLKSCTRYLTKCNY-HASAKLLAVKTFSMPAMSPTMEKGGIVSWKYKVGEPFSAGDVILEV 69

  Fly   118 ETDKATMGFETPEEGFLAKILIQGGTKDVPVGQLLCIIVPDQGSVAAFANFKDDGAAAAPAAPAA 182
            ||||:.:..|..::|.|||||...|:|||.||:          .:|..|:..||      .|...
Yeast    70 ETDKSQIDVEALDDGKLAKILKDEGSKDVDVGE----------PIAYIADVDDD------LATIK 118

  Fly   183 APAPAPAAAAAPPPPPPPAAAPAAAAP--------PPAPAAAPAAAGTGRVYASPMAKRLAE--- 236
            .|..|..|.|.......|:|....|..        .|......:.|...:.....::..|||
Yeast   119 LPQEANTANAKSIEIKKPSADSTEATQQHLKKATVTPIKTVDGSQANLEQTLLPSVSLLLAENNI 183

  Fly   237 -AQQLRLQGKGSGVHGSIKSGDLAGQKAAAKPAAAAPAKAPRAAG-------ARYEDIPVTNMRA 293
             .|:...:...||.:|.:..||:          .|...|.|:.:.       .:.|.:.::|::.
Yeast   184 SKQKALKEIAPSGSNGRLLKGDV----------LAYLGKIPQDSVNKVTEFIKKNERLDLSNIKP 238

  Fly   294 VIAKRLL--ESKTQLPHYYVTVQCQVDKLLKFRAKVNKKYEKQGARVSVNDFIIKAVAIA-SLKV 355
            :..|..:  :::|:..........:.::.|.|.|..:..::|...  |:|.|:.:|...: ...:
Yeast   239 IQLKPKIAEQAQTKAADKPKITPVEFEEQLVFHAPASIPFDKLSE--SLNSFMKEAYQFSHGTPL 301

  Fly   356 PEANSAWMDTVIRKYDDVDVSVAVSTDKGLITPIVFNADRKGVLEISKDVKALAAKARDNKLQPH 420
            .:.||.:.|.:   ::|                :|..:.|:...:.|.|:..:   .:.|.:|..
Yeast   302 MDTNSKYFDPI---FED----------------LVTLSPREPRFKFSYDLMQI---PKANNMQDT 344

  Fly   421 EFQGGTISVSNLGMFGVNQFAAVINPPQSCILAIGTTTKQLVADPDSLKGFKEVN--MLTVTLSA 483
            ..|.....:    :.|.:..|:.:.|.:                    |...|.|  :|.:.:|.
Yeast   345 YGQEDIFDL----LTGSDATASSVRPVE--------------------KNLPEKNEYILALNVSV 385

  Fly   484 DHRVVDGAVAARWLQHFRDYMED 506
            :::..:.|.|.  .:.|.||:.:
Yeast   386 NNKKFNDAEAK--AKRFLDYVRE 406

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
muc	NP_001260196.1	PDHac_trf_mito	83..512	CDD:273567	96/448 (21%)
		lipoyl_domain	83..155	CDD:133458	34/71 (48%)
		2-oxoacid_dh	299..512	CDD:278621	33/213 (15%)
PDX1	NP_011709.1	AceF	31..410	CDD:223582	96/452 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0508
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S865
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23151
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.860