Protein Alignment muc and PDHX

DIOPT Version :10

• Sequence 1: NP_609118.1
• Gene: muc / 34021
• FlyBaseID: FBgn0283658
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: NP_003468.2
• Gene: PDHX / 8050
• HGNCID: 21350
• Length: 501
• Species: Homo sapiens
• Alignment Length: 470
• Identity: 180/470 - (38%)
• Similarity: 258/470 - (54%)
• Gaps: 72/470 - (15%)

  Fly    81 IRVPLPALSPTMERGSIVSWEKKEGDKLNEGDLLCEIETDKATMGFETPEEGFLAKILIQGGTKD 145
            |::.:|:||||||.|:||.|.||||:.::.||.|||||||||.:..:..::|.||||:::.|:|:
Human    57 IKILMPSLSPTMEEGNIVKWLKKEGEAVSAGDALCEIETDKAVVTLDASDDGILAKIVVEEGSKN 121

  Fly   146 VPVGQLLCIIVPDQGSVAAFANFKDDGAAAAPAAPAAAPAPAPAAAAAPPPPPPPAAAPAAAAPP 210
            :.:|.|:.:||.:..........||.|                        ||||.:.|:...|.
Human   122 IRLGSLIGLIVEEGEDWKHVEIPKDVG------------------------PPPPVSKPSEPRPS 162

  Fly   211 PAP-AAAPA----AAGTGRVYASPMAKRLAEAQQL-RLQGKGSGVHGSIKSGD---LAGQKAAAK 266
            |.| .:.|.    ..||.|...||.|:.:.|...| ..||..:|..|.....|   |...|...|
Human   163 PEPQISIPVKKEHIPGTLRFRLSPAARNILEKHSLDASQGTATGPRGIFTKEDALKLVQLKQTGK 227

  Fly   267 -------------PAAAAPAKA-------------------PRAAGARYEDIPVTNMRAVIAKRL 299
                         |.|.:|.:|                   |.|.|. :.:||.:|:|.||||||
Human   228 ITESRPTPAPTATPTAPSPLQATAGPSYPRPVIPPVSTPGQPNAVGT-FTEIPASNIRRVIAKRL 291

  Fly   300 LESKTQLPHYYVTVQCQVDKLLKFRAKVNKKYEKQGARVSVNDFIIKAVAIASLKVPEANSAWMD 364
            .|||:.:||.|.|..|.:..:|    ||.:...|...:||||||||||.|:...::|:.|.:|..
Human   292 TESKSTVPHAYATADCDLGAVL----KVRQDLVKDDIKVSVNDFIIKAAAVTLKQMPDVNVSWDG 352

  Fly   365 TVIRKYDDVDVSVAVSTDKGLITPIVFNADRKGVLEISKDVKALAAKARDNKLQPHEFQGGTISV 429
            ...::...:|:||||:|||||:|||:.:|..||:.||:..||||:.||||.||.|.|:|||:.|:
Human   353 EGPKQLPFIDISVAVATDKGLLTPIIKDAAAKGIQEIADSVKALSKKARDGKLLPEEYQGGSFSI 417

  Fly   430 SNLGMFGVNQFAAVINPPQSCILAIG--TTTKQLVADPDSLKGFKEVNMLTVTLSADHRVVDGAV 492
            |||||||:::|.|||||||:||||:|  ....:|..|.:.....::..::|||:|:|.||||..:
Human   418 SNLGMFGIDEFTAVINPPQACILAVGRFRPVLKLTEDEEGNAKLQQRQLITVTMSSDSRVVDDEL 482

  Fly   493 AARWLQHFRDYMEDP 507
            |.|:|:.|:..:|:|
Human   483 ATRFLKSFKANLENP 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
muc	NP_609118.1	PDHac_trf_mito	83..512	CDD:273567	179/468 (38%)
PDHX	NP_003468.2	PDHac_trf_mito	58..500	CDD:273567	179/469 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	142..175		12/56 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	225..268		5/42 (12%)