Protein Alignment muc and lat1

DIOPT Version :9

• Sequence 1: NP_001260196.1
• Gene: muc / 34021
• FlyBaseID: FBgn0283658
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: NP_587755.1
• Gene: lat1 / 2538797
• PomBaseID: SPCC794.07
• Length: 483
• Species: Schizosaccharomyces pombe
• Alignment Length: 504
• Identity: 223/504 - (44%)
• Similarity: 311/504 - (61%)
• Gaps: 38/504 - (7%)

  Fly    24 NATYVRR-STGNVVVRALSSQLINSRKLQSIRSKLNTSQSPVTWSYNFARAYA--NLPEHIRVPL 85
            :|..:|| ..|..|.|.|   |:::.|:|..:|.|    .||  ....||.||  |.|.|..:.:
pombe     3 SANMLRRMHHGVAVTRML---LVSNGKVQVKKSAL----YPV--MAKLARTYATKNYPAHTVINM 58

  Fly    86 PALSPTMERGSIVSWEKKEGDKLNEGDLLCEIETDKATMGFETPEEGFLAKILIQGGTKDVPVGQ 150
            |||||||..|:|.:::||.|||:..||:|||||||||.:.||..:||:||||||:.||||||||:
pombe    59 PALSPTMTTGNIGAFQKKIGDKIEPGDVLCEIETDKAQIDFEQQDEGYLAKILIETGTKDVPVGK 123

  Fly   151 LLCIIVPDQGSVAAFANFK-DDGAAAAPAAPAAAPAPAPAAAAAPPPPPPPAAAPAAAAPPPAPA 214
            .|.:.|.::|.|||.|:|. :|.:|..|:|.:.....||             ::...:....:|:
pombe   124 PLAVTVENEGDVAAMADFTIEDSSAKEPSAKSGEEKSAP-------------SSEKQSKETSSPS 175

  Fly   215 AAPAAAGTGRVYASPMAKRLAEAQQLRL-QGKGSGVHGSIKSGDLAGQK----------AAAKPA 268
            .........||:|||:|::|||.:.|.| |.:|||.:|.|...|:...|          ||||..
pombe   176 NVSGEERGDRVFASPLARKLAEEKDLDLSQIRGSGPNGRIIKVDIENFKPVVAPKPSNEAAAKAT 240

  Fly   269 AAAPAKAPRAAGARYEDIPVTNMRAVIAKRLLESKTQLPHYYVTVQCQVDKLLKFRAKVNKKYEK 333
            ..|.:.|..||...|||:|::|||.:||.||.|||...|||||||...::|:::.||.:|...:.
pombe   241 TPAASAADAAAPGDYEDLPLSNMRKIIASRLAESKNMNPHYYVTVSVNMEKIIRLRAALNAMADG 305

  Fly   334 QGARVSVNDFIIKAVAIASLKVPEANSAWMDTVIRKYDDVDVSVAVSTDKGLITPIVFNADRKGV 398
            : .::||||.:|||...|..:|||.|:|||...||:|.:||:|:||:|..|||||::.|....|:
pombe   306 R-YKLSVNDLVIKATTAALRQVPEVNAAWMGDFIRQYKNVDISMAVATPSGLITPVIRNTHALGL 369

  Fly   399 LEISKDVKALAAKARDNKLQPHEFQGGTISVSNLGMFGVNQFAAVINPPQSCILAIGTTTKQLVA 463
            .|||...|....:||:|||:|.|:||||.::||||||.|:||.|:|||||:||||:|||...:|.
pombe   370 AEISTLAKDYGQRARNNKLKPEEYQGGTFTISNLGMFPVDQFTAIINPPQACILAVGTTVDTVVP 434

  Fly   464 DPDSLKGFKEVNMLTVTLSADHRVVDGAVAARWLQHFRDYMEDPSNMVL 512
            |..|.||||...::..|||:||||||||:|||:....:..:|:|..::|
pombe   435 DSTSEKGFKVAPIMKCTLSSDHRVVDGAMAARFTTALKKILENPLEIML 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
muc	NP_001260196.1	PDHac_trf_mito	83..512	CDD:273567	201/440 (46%)
		lipoyl_domain	83..155	CDD:133458	44/71 (62%)
		2-oxoacid_dh	299..512	CDD:278621	106/212 (50%)
lat1	NP_587755.1	lipoyl_domain	54..127	CDD:133458	44/72 (61%)
		PDHac_trf_mito	55..483	CDD:273567	201/441 (46%)
		E3_binding	187..220	CDD:280908	15/32 (47%)
		2-oxoacid_dh	271..483	CDD:278621	106/212 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	236	1.000	Domainoid score	I478
eggNOG	1	0.900	-	-		E1_COG0508
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6814
Inparanoid	1	1.050	375	1.000	Inparanoid score	I434
OMA	1	1.010	-	-		QHG62888
OrthoFinder	1	1.000	-	-		FOG0001572
OrthoInspector	1	1.000	-	-		oto100749
orthoMCL	1	0.900	-	-		OOG6_101258
Panther	1	1.100	-	-	LDO	PTHR23151
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R863
SonicParanoid	1	1.000	-	-		X2175
TreeFam	1	0.960	-	-
	14	13.860