Protein Alignment muc and DLST

DIOPT Version :10

• Sequence 1: NP_609118.1
• Gene: muc / 34021
• FlyBaseID: FBgn0283658
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: NP_001924.2
• Gene: DLST / 1743
• HGNCID: 2911
• Length: 453
• Species: Homo sapiens
• Alignment Length: 484
• Identity: 145/484 - (29%)
• Similarity: 215/484 - (44%)
• Gaps: 93/484 - (19%)

  Fly    46 NSRKLQSIRSKLNTSQSPVTWSYNFARAYANLPEH-IRVPLPALSPTMERGSIVSWEKKEGDKLN 109
            ||||:     .:|.|    .:|..|.|..|...:. :.|..||.:.::..|. |.|||..||.:.
Human    44 NSRKV-----VINNS----VFSVRFFRTTAVCKDDLVTVKTPAFAESVTEGD-VRWEKAVGDTVA 98

  Fly   110 EGDLLCEIETDKATMGFETPEEGFLAKILIQGGTKDVPVGQLLCIIVPDQGSV---AAFANFKDD 171
            |.:::|||||||.::...:|..|.:..:|                 |||.|.|   ......:..
Human    99 EDEVVCEIETDKTSVQVPSPANGVIEALL-----------------VPDGGKVEGGTPLFTLRKT 146

  Fly   172 GAAAAPAAPAAAPAPA-----PAAAAAPPPPPPPAAAPAAAAPPPAPAAAPAAAGTGRVYASPMA 231
            |||.|.|.||.|||.|     |.|||.|||     |||.....||.|:.:...:|      .|:
Human   147 GAAPAKAKPAEAPAAAAPKAEPTAAAVPPP-----AAPIPTQMPPVPSPSQPPSG------KPV- 199

  Fly   232 KRLAEAQQLRLQGKGSGVHGSIKSGDLAGQKAAAKPAAAAPAKAPRAA-GARYEDIPVTN-MRAV 294
                                           :|.||..|.|...|.|. |.|.|.....| ||..
Human   200 -------------------------------SAVKPTVAPPLAEPGAGKGLRSEHREKMNRMRQR 233

  Fly   295 IAKRLLESKTQLPHYYVTVQCQVDKLLKFRAKVNKKY-EKQGARVSVNDFIIKAVAIASLKVPEA 358
            ||:||.|::..........:..:..:.:.||:..:.: :|...::......:||.|.|..:.|..
Human   234 IAQRLKEAQNTCAMLTTFNEIDMSNIQEMRARHKEAFLKKHNLKLGFMSAFVKASAFALQEQPVV 298

  Fly   359 NSAWMDT----VIRKYDDVDVSVAVSTDKGLITPIVFNADRKGVLEISKDVKALAAKARDNKLQP 419
            |:...||    |.|.|  :|:||||:|.:||:.|::.|.:.....:|.:.:..|..|||.|:|..
Human   299 NAVIDDTTKEVVYRDY--IDISVAVATPRGLVVPVIRNVEAMNFADIERTITELGEKARKNELAI 361

  Fly   420 HEFQGGTISVSNLGMFGVNQFAAVINPPQSCILAIGTTTKQLVADPDSLKGFKEVN-MLTVTLSA 483
            .:..|||.::||.|:||......:||||||.||.:    ..:...|.::.|..||. |:.|.|:.
Human   362 EDMDGGTFTISNGGVFGSLFGTPIINPPQSAILGM----HGIFDRPVAIGGKVEVRPMMYVALTY 422

  Fly   484 DHRVVDGAVAARWLQHFRDYMEDPSNMVL 512
            |||::||..|..:|:..:..:|||..::|
Human   423 DHRLIDGREAVTFLRKIKAAVEDPRVLLL 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
muc	NP_609118.1	PDHac_trf_mito	83..512	CDD:273567	134/444 (30%)
DLST	NP_001924.2	sucB	71..453	CDD:273565	135/448 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	152..225		32/115 (28%)