Protein Alignment muc and Dbt

DIOPT Version :10

• Sequence 1: NP_609118.1
• Gene: muc / 34021
• FlyBaseID: FBgn0283658
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: NP_034152.2
• Gene: Dbt / 13171
• MGIID: 105386
• Length: 482
• Species: Mus musculus
• Alignment Length: 522
• Identity: 116/522 - (22%)
• Similarity: 204/522 - (39%)
• Gaps: 125/522 - (23%)

  Fly    65 TWSYNFAR-----------------------------AYANLPEH------------IRVPLPAL 88
            |||.|..|                             .|:. |.|            ::..|..:
Mouse     9 TWSQNAVRLTCVRYFQTFNSARVLKPKCVCSVGYPLFKYSQ-PRHSLRTAAVLQGQVVQFKLSDI 72

  Fly    89 SPTMERGSIVSWEKKEGDKLNEGDLLCEIETDKATMGFETPEEGFLAKILIQGGTKDVP-VGQLL 152
            ...:...:|..|..||||.:::.|.:||:::|||::...:..:|.:.::..  ...|:. ||:.|
Mouse    73 GEGIREVTIKEWYVKEGDTVSQFDSICEVQSDKASVTITSRYDGVIKRLYY--NLDDIAYVGKPL 135

  Fly   153 CIIVPDQGSVAAFANFKDDGAAAAPAAPAAAPAPAPAAAAAPPPPPPPAAAPAAAAPPPAPAAAP 217
            ..|     ...|..:.::|                            ....||.:..........
Mouse   136 IDI-----ETEALKDSEED----------------------------VVETPAVSHDEHTHQEIK 167

  Fly   218 AAAGTGRVYASPMAKRLAEAQQLRL-QGKGSGVHGSIKSGDL-------------AGQKAAAKPA 268
            ..    :..|:|..:|||....::| :..|||..|.|...|:             ...|:...|.
Mouse   168 GQ----KTLATPAVRRLAMENNIKLSEVVGSGKDGRILKEDILSFLEKQTGAILPPSPKSEITPP 228

  Fly   269 AAAP---------AKAPRAAGA-RYEDIPVTNMRAVIAKRLLESKTQLPHYYVTVQCQVDKLLKF 323
            ...|         ||.|...|. |.|  |||..:..:.| .:.:..::||:....:..:.:|:|.
Mouse   229 PPQPKDRTFPTPIAKPPVFTGKDRTE--PVTGFQKAMVK-TMSAALKIPHFGYCDEIDLTQLVKL 290

  Fly   324 RAKVNKKYEKQGARVSVNDFIIKAVAIASLKVPEANSAWMDTVIRKYDDV------DVSVAVSTD 382
            |.::......:|.::|...|.:||.::..|:.|..|:    :|.....::      ::.:|:.|:
Mouse   291 REELKPVALARGIKLSFMPFFLKAASLGLLQFPILNA----SVDENCQNITYKASHNIGIAMDTE 351

  Fly   383 KGLITPIVFNADRKGVLEISKDVKALAAKARDNKLQPHEFQGGTISVSNLGMFGVNQFAAVINPP 447
            .|||.|.|.|...:.|.||:.::..|.......:|...:..|||.::||:|..|......||.||
Mouse   352 LGLIVPNVKNVQVRSVFEIAMELNRLQKLGSSGQLGTTDLTGGTFTLSNIGSIGGTYAKPVILPP 416

  Fly   448 QSCILAIGTTTKQLVADP--DSLKGFKEVNMLTVTLSADHRVVDGAVAARWLQHFRDYMEDPSNM 510
            :..|.|:|.    :.|.|  |......:..::.|:.||||||:|||..:|:...::.|:|:|:.|
Mouse   417 EVAIGALGA----IKALPRFDQKGDVYKAQIMNVSWSADHRVIDGATMSRFSNLWKSYLENPAFM 477

  Fly   511 VL 512
            :|
Mouse   478 LL 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
muc	NP_609118.1	PDHac_trf_mito	83..512	CDD:273567	107/461 (23%)
Dbt	NP_034152.2	PLN02528	67..482	CDD:215289	108/463 (23%)
		Critical for association with PPM1K. /evidence=ECO:0000250|UniProtKB:P11182	145..160		3/42 (7%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	217..252		7/34 (21%)