DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15818 and CLEC6A

DIOPT Version :9

Sequence 1:	NP_609116.1	Gene:	CG15818 / 34019	FlyBaseID:	FBgn0031910	Length:	283	Species:	Drosophila melanogaster
Sequence 2:	NP_001007034.1	Gene:	CLEC6A / 93978	HGNCID:	14556	Length:	209	Species:	Homo sapiens

Alignment Length:	103	Identity:	35/103 - (33%)
Similarity:	55/103 - (53%)	Gaps:	11/103 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   159 YQQIGSRYFYIEHNLQVNWRTAEQRCIEMGGHLAAFQNAEEYNAIVGQLNKA-NYWLGVNDLAKQ 222
            ::..||..::|....:| |..:||.|:|||.||..|....|.|.||.|||:: :|:||::|  .|
Human    83 WKSFGSSCYFISSEEKV-WSKSEQNCVEMGAHLVVFNTEAEQNFIVQQLNESFSYFLGLSD--PQ 144

  Fly   223 G----EFISLASGKRATYFKWRKNEPKYNNPTQHCAYV 256
            |    ::|.....::...| |...||  |:..:.||.:
Human   145 GNNNWQWIDKTPYEKNVRF-WHLGEP--NHSAEQCASI 179

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15818	NP_609116.1	CLECT	164..278	CDD:153057	34/98 (35%)
CLEC6A	NP_001007034.1	CLECT_DC-SIGN_like	79..204	CDD:153060	35/103 (34%)
		Alpha-D-mannopyranose binding. /evidence=ECO:0000269\|PubMed:28652405, ECO:0007744\|PDB:5VYB	168..170		2/3 (67%)
		Alpha-D-mannopyranose binding. /evidence=ECO:0000269\|PubMed:28652405, ECO:0007744\|PDB:5VYB	190..191
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	49	1.000	Domainoid score	I11773
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22802
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.010