Protein Alignment CG15818 and SFTPD

DIOPT Version :10

• Sequence 1: NP_609116.1
• Gene: CG15818 / 34019
• FlyBaseID: FBgn0031910
• Length: 283
• Species: Drosophila melanogaster
• Sequence 2: NP_003010.4
• Gene: SFTPD / 6441
• HGNCID: 10803
• Length: 375
• Species: Homo sapiens
• Alignment Length: 157
• Identity: 36/157 - (22%)
• Similarity: 70/157 - (44%)
• Gaps: 23/157 - (14%)

  Fly   116 KDIEGNQTALSN-------QLKDGQKRTENQLTAIQKTLSDIERKLVLQRYQQIGSRYF----YI 169
            |.|.|::.|...       .|:...:..:.|:..:|...|..::..:....|.:|.:.|    ::
Human   207 KGIPGDKGAKGESGLPDVASLRQQVEALQGQVQHLQAAFSQYKKVELFPNGQSVGEKIFKTAGFV 271

  Fly   170 EHNLQVNWRTAEQRCIEMGGHLAAFQNAEEYNAIVGQL----NKANYWLGVNDLAKQGEFISLAS 230
            :     .:..|:..|.:.||.||:.::|.| ||.:.||    |:|.: |.:.|...:|:| :..:
Human   272 K-----PFTEAQLLCTQAGGQLASPRSAAE-NAALQQLVVAKNEAAF-LSMTDSKTEGKF-TYPT 328

  Fly   231 GKRATYFKWRKNEPKYNNPTQHCAYVF 257
            |:...|..|...||..:..::.|..:|
Human   329 GESLVYSNWAPGEPNDDGGSEDCVEIF 355

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15818	NP_609116.1	MscS_porin	<75..>165	CDD:432790	10/55 (18%)
		CLECT	164..278	CDD:153057	26/102 (25%)
SFTPD	NP_003010.4	gly_rich_SclB	<44..>220	CDD:468478	4/12 (33%)
		Surfac_D-trimer	224..269	CDD:286141	7/44 (16%)
		CLECT_collectin_like	262..375	CDD:153061	26/102 (25%)