DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15818 and FCER2

DIOPT Version :9

Sequence 1:	NP_609116.1	Gene:	CG15818 / 34019	FlyBaseID:	FBgn0031910	Length:	283	Species:	Drosophila melanogaster
Sequence 2:	NP_001207429.1	Gene:	FCER2 / 2208	HGNCID:	3612	Length:	321	Species:	Homo sapiens

Alignment Length:	206	Identity:	44/206 - (21%)
Similarity:	81/206 - (39%)	Gaps:	43/206 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 DKIEDQLTATQIQIEAQQAFLVNNISKAIKTEDLEQKLKDIEGNQTALS----------NQLKDG 132
            |::..:..:|||..|.::   :....:.:|::|||... ::.|.|..||          |:..|.
Human    77 DQMAQKSQSTQISQELEE---LRAEQQRLKSQDLELSW-NLNGLQADLSSFKSQELNERNEASDL 137

  Fly   133 QKRTENQLTAIQKTLS---------------DIERKLVLQRYQQIGSRYFYIEHNLQVNWRTAEQ 182
            .:|...::|.::..|.               :.:||.           |::.:...|  |..|..
Human   138 LERLREEVTKLRMELQVSSGFVCNTCPEKWINFQRKC-----------YYFGKGTKQ--WVHARY 189

  Fly   183 RCIEMGGHLAAFQNAEEYNAIVGQLNKANYWLGVNDLAKQGEFISLASGKRATYFKWRKNEPKYN 247
            .|.:|.|.|.:..:.||.:.:....:....|:|:.:|..:|||| ...|....|..|...||...
Human   190 ACDDMEGQLVSIHSPEEQDFLTKHASHTGSWIGLRNLDLKGEFI-WVDGSHVDYSNWAPGEPTSR 253

  Fly   248 NPTQHCAYVFG 258
            :..:.|..:.|
Human   254 SQGEDCVMMRG 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15818	NP_609116.1	CLECT	164..278	CDD:153057	24/95 (25%)
FCER2	NP_001207429.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	66..85		1/7 (14%)
		Repetitive region	69..89		3/11 (27%)
		RILP-like	<77..153	CDD:304877	17/79 (22%)
		Repetitive region	90..110		5/22 (23%)
		Repetitive region	111..131		4/20 (20%)
		CLECT	163..282	CDD:214480	26/116 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	290..321
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22802
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010