DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15818 and CLEC4C

DIOPT Version :9

Sequence 1:	NP_609116.1	Gene:	CG15818 / 34019	FlyBaseID:	FBgn0031910	Length:	283	Species:	Drosophila melanogaster
Sequence 2:	NP_001358319.1	Gene:	CLEC4C / 170482	HGNCID:	13258	Length:	213	Species:	Homo sapiens

Alignment Length:	147	Identity:	31/147 - (21%)
Similarity:	53/147 - (36%)	Gaps:	55/147 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   150 IERKLVLQRYQQ--------------------------IGSRYFYIEHNLQVNWRTAEQRCIEMG 188
            ::|...|:.|||                          ..|..::|...:| :|..:::.|..||
Human    52 VKRLSKLREYQQYHPSLTCVMEGKDIEDWSCCPTPWTSFQSSCYFISTGMQ-SWTKSQKNCSVMG 115

  Fly   189 GHLAAFQNAEEYNAIVGQLNK-ANYWLGVNDLAKQGEFISLASGKR-------------ATYFKW 239
            ..|......||.:.|:..|.: ::|:||::|          ..|:|             .|:  |
Human   116 ADLVVINTREEQDFIIQNLKRNSSYFLGLSD----------PGGRRHWQWVDQTPYNENVTF--W 168

  Fly   240 RKNEPKYNNPTQHCAYV 256
            ...||  ||..:.||.:
Human   169 HSGEP--NNLDERCAII 183

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15818	NP_609116.1	CLECT	164..278	CDD:153057	26/107 (24%)
CLEC4C	NP_001358319.1	CLECT_DC-SIGN_like	83..208	CDD:153060	26/116 (22%)
		Carbohydrate binding. /evidence=ECO:0000269\|PubMed:25995448, ECO:0007744\|PDB:4ZET	184..186		31/147 (21%)
		Carbohydrate binding. /evidence=ECO:0000269\|PubMed:25995448, ECO:0007744\|PDB:4ZET	194..195
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	49	1.000	Domainoid score	I11773
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22802
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.010