DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG5160 and RASL12

DIOPT Version :9

Sequence 1:NP_001188708.1 Gene:CG5160 / 34015 FlyBaseID:FBgn0031906 Length:328 Species:Drosophila melanogaster
Sequence 2:NP_057647.1 Gene:RASL12 / 51285 HGNCID:30289 Length:266 Species:Homo sapiens


Alignment Length:243 Identity:76/243 - (31%)
Similarity:116/243 - (47%) Gaps:33/243 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 TSPKSSLVKLGLHTNKQKTLKVMVLGQSGVGKTAMVVRFITRRFIGEYDPNLEKIYTCQTTLDKE 68
            :.|:|:.:::.|          .:||:.|.||:|:.|:|:|:|||.|||||||..|:.:.|:|.:
Human    12 SGPQSAPLEVNL----------AILGRRGAGKSALTVKFLTKRFISEYDPNLEDTYSSEETVDHQ 66

  Fly    69 QIQFDILDATGQLQELDGV-SLESNIRWADAFILMYSITDKCSFDECSRLKFLINYNKRRRKLGS 132
            .:...::|..    :||.. :.|..:.||.||:::||:..:.|||..|....|         |..
Human    67 PVHLRVMDTA----DLDTPRNCERYLNWAHAFLVVYSVDSRQSFDSSSSYLEL---------LAL 118

  Fly   133 ASKEYALDIPVILVGNKTDQPGDRMVSLEEGQRRFRELSCSCFHEISVRESVDQVQNVFRDVFR- 196
            .:||....||.:|:|||.|....|.|:..||........| .|.|:|.....:.||:||.:..| 
Human   119 HAKETQRSIPALLLGNKLDMAQYRQVTKAEGVALAGRFGC-LFFEVSACLDFEHVQHVFHEAVRE 182

  Fly   197 FWRVFSKFPKLKR----STSDVANTDGILTPDSG--SCSFYDASSLGV 238
            ..|...|.| |.|    |..........||...|  ||:|...|::.:
Human   183 ARRELEKSP-LTRPLFISEERALPHQAPLTARHGLASCTFNTLSTINL 229

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5160NP_001188708.1 small_GTPase 21..196 CDD:197466 59/175 (34%)
RERG_RasL11_like 24..200 CDD:206713 60/177 (34%)
RASL12NP_057647.1 RERG_RasL11_like 22..185 CDD:206713 61/186 (33%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0395
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1384728at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.820

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