DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gudu and ARABIDILLO-1

DIOPT Version :9

Sequence 1:	NP_609111.1	Gene:	gudu / 34014	FlyBaseID:	FBgn0031905	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	NP_001325003.1	Gene:	ARABIDILLO-1 / 819099	AraportID:	AT2G44900	Length:	930	Species:	Arabidopsis thaliana

Alignment Length:	669	Identity:	139/669 - (20%)
Similarity:	244/669 - (36%)	Gaps:	162/669 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    87 VSLCC--LKDYDL-------STQINQFA-----ISDIGGLDVL---------------VNILECS 122
            |:.||  ||...|       |..|...|     ::|:|.||.|               :::...|
plant   181 VAFCCPKLKKLRLSGIRDVTSEAIEALAKHCPQLNDLGFLDCLNIDEEALGKVVSVRYLSVAGTS 245

  Fly   123 DTKCCLGA--LKVLSDITLNIDIRKTIVDLDGIPLIVDILNSSMKDLKTMAA---------ETLA 176
            :.|..:.:  ...|..:| .:|:.:|.:.    |..|....:|.:.||.:.|         |:|.
plant   246 NIKWSIASNNWDKLPKLT-GLDVSRTDIG----PTAVSRFLTSSQSLKVLCALNCHVLEEDESLI 305

  Fly   177 NVCKVR---LARKYVRTCGGI----------PKLVDLIDIKLSILKTPRD--------------- 213
            :..:.:   |...:.....|:          ||  |:......::||.:|
plant   306 SYNRFKGKVLLALFTNVFDGLASIFADNTKKPK--DIFAYWRELMKTTKDKTINDFIHWIEWIIS 368

  Fly   214 -------QLSPDDLESLDMTRAGARALFTLADSKHNMEQMRKSGIVPLMAQLLKSCHIDVVIPIM 271
                   :.:|:.|:...:....|..|..:..|:.::::...:|:...:....::..||
plant   369 HTLLRTAECNPEGLDDFWLNEGAALLLNLMQSSQEDVQERSATGLATFVVVDDENASID------ 427

  Fly   272 GTVRKCSSEPKFQLAITTEGMIPDIVSHLSSENTELKMEGSTAIYKCAFDGTTRDLVREAGGLEP 336
                 |....    |:..:|.|..::....|....|:.|.:.||...:.:......|.|.||::.
plant   428 -----CGRAE----AVMKDGGIRLLLELAKSWREGLQSEAAKAIANLSVNANIAKSVAEEGGIKI 483

  Fly   337 LVTIIKDKNVRENKPLLRGATGAIWMCAVTDANVKVLDQLRTVNHLVALL---NDECDEVLTNVT 398
            |..:.|..    |:.:...|.|.:|..:|.:.:...:.|...|..||.|:   .:.||.||....
plant   484 LAGLAKSM----NRLVAEEAAGGLWNLSVGEEHKNAIAQAGGVKALVDLIFRWPNGCDGVLERAA 544

  Fly   399 GAISECVRFQSNREQLRQAGGLPAMVSLL-NSSHAPLLENLAKGLKECAEDPDSMRILEDLDAVR 462
            ||::..........::.:|||:.|:|.|. |..:..:.|..|:.|...|...||
plant   545 GALANLAADDKCSMEVAKAGGVHALVMLARNCKYEGVQEQAARALANLAAHGDS----------- 598

  Fly   463 LIWSLLKNPTTRVQAHAAYAICPCVRNANDSAELVRSLVGAMELVVGLLKSKDIMVLSAVCAAIA 527
                                      |.|::|  |....||:|.:|.|.||....|......|:.
plant   599 --------------------------NNNNAA--VGQEAGALEALVQLTKSPHEGVRQEAAGALW 635

  Fly   528 TIAQDQTN---LAILTDLKVIYKLADLVQTTDDLLRMNLAAAVAACACFGNNTEELGRLRTVTPI 589
            .::.|..|   :::...::.:..||.........|:...|.|:...:....|:..:||...|.|:
plant   636 NLSFDDKNRESISVAGGVEALVALAQSCSNASTGLQERAAGALWGLSVSEANSVAIGREGGVPPL 700

  Fly   590 VTYMTSDNPLVHRSTAMALEKLSMDPQNCITMHQSGVVPFLLE-CIGSTNKELQLAAAGCLRNIR 653
            :....|:...||.:.|.||..|:.:|.|.:.:.:.|.||.|:. |..|.:|..:..||
plant   701 IALARSEAEDVHETAAGALWNLAFNPGNALRIVEEGGVPALVHLCSSSVSKMARFMAA------- 758

  Fly   654 ELAL------RAEEYLLKI 666
             |||      |.:||.|.|
plant   759 -LALAYMFDGRMDEYALMI 776

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gudu	NP_609111.1	armadillo repeat	105..134	CDD:293788	8/50 (16%)
		armadillo repeat	144..180	CDD:293788	9/44 (20%)
		Arm_3	214..557	CDD:330530	69/349 (20%)
		armadillo repeat	245..275	CDD:293788	3/29 (10%)
		armadillo repeat	286..318	CDD:293788	8/31 (26%)
		armadillo repeat	328..362	CDD:293788	9/33 (27%)
		armadillo repeat	411..447	CDD:293788	10/36 (28%)
		armadillo repeat	453..484	CDD:293788	0/30 (0%)
		armadillo repeat	494..526	CDD:293788	10/31 (32%)
		ARM	614..652	CDD:214547	11/38 (29%)
		armadillo repeat	619..652	CDD:293788	9/33 (27%)
ARABIDILLO-1	NP_001325003.1	F-box-like	47..91	CDD:403981
		leucine-rich repeat	54..76	CDD:275381
		leucine-rich repeat	88..107	CDD:275381
		leucine-rich repeat	134..159	CDD:275381
		AMN1	143..>225	CDD:187754	14/43 (33%)
		leucine-rich repeat	160..187	CDD:275381	3/5 (60%)
		leucine-rich repeat	188..213	CDD:275381	6/24 (25%)
		leucine-rich repeat	214..235	CDD:275381	5/20 (25%)
		leucine-rich repeat	236..261	CDD:275381	3/24 (13%)
		leucine-rich repeat	262..286	CDD:275381	6/28 (21%)
		PLN03200	<388..>506	CDD:215629	25/136 (18%)
		armadillo repeat	433..465	CDD:293788	8/31 (26%)
		armadillo repeat	471..508	CDD:293788	10/40 (25%)
		Arm	599..638	CDD:395413	13/40 (33%)
		PLN03200	608..>784	CDD:215629	47/177 (27%)
		armadillo repeat	612..637	CDD:293788	7/24 (29%)
		armadillo repeat	644..682	CDD:293788	5/37 (14%)
		Arm	684..723	CDD:395413	11/38 (29%)
		armadillo repeat	688..722	CDD:293788	10/33 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		oto3917
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910