DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gudu and odad2

DIOPT Version :9

Sequence 1:	NP_609111.1	Gene:	gudu / 34014	FlyBaseID:	FBgn0031905	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	NP_001072494.1	Gene:	odad2 / 779949	XenbaseID:	XB-GENE-982927	Length:	1053	Species:	Xenopus tropicalis

Alignment Length:	660	Identity:	305/660 - (46%)
Similarity:	443/660 - (67%)	Gaps:	23/660 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 TSSGTSHNRSRKKKEQCGSCPNRFSKDKRQVAAEDSDTTEVESSTDEEERWKEVARAAEIPADYY 68
            |::.:...||..|.:..|:..:.||:            :..||..|||:..:......::|::|:
Frog   411 TNAHSVVRRSALKSKTPGAKSDEFSE------------SSTESEEDEEQPERRQEGNTDLPSEYW 463

  Fly    69 NIQKLVKYIKAGNQTATIVSLCCLKDYDLSTQINQFAISDIGGLDVLVNILECSDTKCCLGALKV 133
            .|||||||:|.||||||:::||.::|::|:.:..|.||.|:||||:|:|:|...:.||.:||||:
Frog   464 QIQKLVKYLKGGNQTATVIALCSIRDFNLAQETCQLAIRDVGGLDILINLLNTEEIKCKIGALKI 528

  Fly   134 LSDITLNIDIRKTIVDLDGIPLIVDILNSSMKDLKTMAAETLANVCKVRLARKYVRTCGGIPKLV 198
            |.:|:.|..||..|.||.|:..:|.||:|..||||.:||||:|||.|.|.||:.||..|||.:||
Frog   529 LKEISHNSQIRSAIADLGGLQTMVGILDSQDKDLKCLAAETIANVAKFRRARRTVRQHGGIRRLV 593

  Fly   199 DLIDIKLSILKTP--RDQLSPDDLESLDMTRAGARALFTLADSKHNMEQMRKSGIVPLMAQLLKS 261
            .|:|.      .|  ...||....:.:::.|.||.||::.:.|..|.|.:||:|.:||:|:||||
Frog   594 GLLDC------APIGSSNLSAQQEKDIEVARCGALALWSCSKSTRNKEAIRKAGGIPLLARLLKS 652

  Fly   262 CHIDVVIPIMGTVRKCSSEPKFQLAITTEGMIPDIVSHLSSENTELKMEGSTAIYKCAFDGTTRD 326
            .|.:::||::||:::|:|||.::|||.||.||.|:|.:|.|||.||:|..::||:|||.|..|||
Frog   653 SHSNMLIPVVGTLQECASEPSYRLAIKTEKMIEDLVKNLKSENPELQMHCASAIFKCAEDEETRD 717

  Fly   327 LVREAGGLEPLVTIIKDKNVRENKPLLRGATGAIWMCAVTDANVKVLDQLRTVNHLVALLNDECD 391
            |||:.|||:||..::   ...|||.||...|||||.|:::..||....:.:.:..||.||.::.:
Frog   718 LVRQYGGLQPLAMLL---GQFENKELLAAVTGAIWKCSISRDNVTKFQEYKVIETLVTLLTNQPE 779

  Fly   392 EVLTNVTGAISECVRFQSNREQLRQAGGLPAMVSLLNSSHAPLLENLAKGLKECAEDPDSMRILE 456
            |||.||.||:.||.:..:||..:|:.||:..:|:||:.::..||.|:.|.:..||.||::|.|::
Frog   780 EVLVNVVGALGECGQEPANRAIIRKCGGISPLVNLLSGTNQALLVNVTKAVGACASDPENMVIID 844

  Fly   457 DLDAVRLIWSLLKNPTTRVQAHAAYAICPCVRNANDSAELVRSLVGAMELVVGLLKSKDIMVLSA 521
            .||.|||:|||||||...|||:||:|||||:.||.|:.|:|||.||.:||:|.||||::..||::
Frog   845 RLDGVRLLWSLLKNPHPDVQANAAWAICPCIENAKDAGEMVRSFVGGLELIVNLLKSENKEVLAS 909

  Fly   522 VCAAIATIAQDQTNLAILTDLKVIYKLADLVQTTDDLLRMNLAAAVAACACFGNNTEELGRLRTV 586
            |||||..||:|:.|||::||..|:..|:.|..||||.||.:||.|::.|..:|:|....|..:.|
Frog   910 VCAAITNIAKDEENLAVITDHGVVALLSALANTTDDKLRRHLAEAISRCCMWGHNRVAFGESKAV 974

  Fly   587 TPIVTYMTSDNPLVHRSTAMALEKLSMDPQNCITMHQSGVVPFLLECIGSTNKELQLAAAGCLRN 651
            .|:|.|:.|.:|||||:||.||.:||.|..||||||::|||..|::.:||.:..||.|||||:.|
Frog   975 APLVHYLKSSDPLVHRATAQALYQLSEDANNCITMHENGVVKLLIDMVGSPDSMLQEAAAGCIAN 1039

  Fly   652 IRELALRAEE 661
            ||.|||..|:
Frog  1040 IRRLALANEK 1049

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gudu	NP_609111.1	armadillo repeat	105..134	CDD:293788	16/28 (57%)
		armadillo repeat	144..180	CDD:293788	20/35 (57%)
		Arm_3	214..557	CDD:330530	164/342 (48%)
		armadillo repeat	245..275	CDD:293788	15/29 (52%)
		armadillo repeat	286..318	CDD:293788	17/31 (55%)
		armadillo repeat	328..362	CDD:293788	16/33 (48%)
		armadillo repeat	411..447	CDD:293788	12/35 (34%)
		armadillo repeat	453..484	CDD:293788	19/30 (63%)
		armadillo repeat	494..526	CDD:293788	18/31 (58%)
		ARM	614..652	CDD:214547	20/37 (54%)
		armadillo repeat	619..652	CDD:293788	17/32 (53%)
odad2	NP_001072494.1	armadillo repeat	465..490	CDD:293788	16/24 (67%)
		ARM	499..602	CDD:237987	54/108 (50%)
		armadillo repeat	500..532	CDD:293788	17/31 (55%)
		armadillo repeat	539..573	CDD:293788	18/33 (55%)
		armadillo repeat	583..626	CDD:293788	17/48 (35%)
		armadillo repeat	634..670	CDD:293788	17/35 (49%)
		ARM	635..749	CDD:237987	61/116 (53%)
		armadillo repeat	675..707	CDD:293788	17/31 (55%)
		ARM	717..830	CDD:237987	47/115 (41%)
		armadillo repeat	719..750	CDD:293788	16/33 (48%)
		armadillo repeat	767..791	CDD:293788	11/23 (48%)
		armadillo repeat	799..835	CDD:293788	12/35 (34%)
		armadillo repeat	840..872	CDD:293788	20/31 (65%)
		ARM	843..957	CDD:237987	65/113 (58%)
		HEAT_2	851..956	CDD:290374	61/104 (59%)
		armadillo repeat	882..917	CDD:293788	20/34 (59%)
		ARM	924..1040	CDD:237987	56/115 (49%)
		armadillo repeat	924..956	CDD:293788	16/31 (52%)
		HEAT_2	932..1034	CDD:290374	48/101 (48%)
		armadillo repeat	1007..1040	CDD:293788	17/32 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9992
Inparanoid	1	1.050	582	1.000	Inparanoid score	I1003
OMA	1	1.010	-	-		QHG52924
OrthoDB	1	1.010	-	-		D185919at33208
OrthoFinder	1	1.000	-	-		FOG0006010
OrthoInspector	1	1.000	-	-		oto102648
Panther	1	1.100	-	-	LDO	PTHR46241
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2332
SonicParanoid	1	1.000	-	-		X4308
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	11.110