DRSC/TRiP Functional Genomics Resources

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Protein Alignment gudu and ctnnb1

DIOPT Version :9

Sequence 1:NP_609111.1 Gene:gudu / 34014 FlyBaseID:FBgn0031905 Length:669 Species:Drosophila melanogaster
Sequence 2:NP_001016958.1 Gene:ctnnb1 / 549712 XenbaseID:XB-GENE-487200 Length:781 Species:Xenopus tropicalis


Alignment Length:551 Identity:111/551 - (20%)
Similarity:184/551 - (33%) Gaps:177/551 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   117 NILECSDTKCCLGALKVLSDITLNIDIRKTIVDLDGIPLIVDILNSSMKDLKTMAAETLAN-VCK 180
            |..:....:|..|.|..||.....:   ..|....|||.:|.:|.|.:..:...|..||.| :..
 Frog   204 NTNDVETARCTAGTLHNLSHHREGL---LAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLH 265

  Fly   181 VRLARKYVRTCGGIPKLVDLI---DIKLSILKTPRDQL----------------SPDDLESLDMT 226
            ...|:..||..||:.|:|.|:   ::|...:.|...|:                .|..|.::..|
 Frog   266 QEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRT 330

  Fly   227 RAGARALFT------------------------------LADSKHNM----------------EQ 245
            .:..:.|:|                              |.||...:                :|
 Frog   331 YSYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDSSQRLVQNCLWTLRNLSDAATKQ 395

  Fly   246 MRKSGIVPLMAQLLKSCHIDVVIPIMGTVRKCSSEPKFQLAITTEGMIPDIVSHLSSENTELKME 310
            ....|::..:.|||.|..|:||....|                       |:|:|:..|.:.|| 
 Frog   396 EGMEGLLGTLVQLLGSDDINVVTCAAG-----------------------ILSNLTCNNYKNKM- 436

  Fly   311 GSTAIYKCAFDGTTRDLVREAGGLEPLVTIIKDKNVRENKPLLRGATGAIWMCAVTDANVKVLDQ 375
                            :|.:.||:|.||..:.....||:               :|:..:..|..
 Frog   437 ----------------MVCQVGGIEALVRTVLRAGDRED---------------ITEPAICALRH 470

  Fly   376 LRTVNH------------------LVALLNDECDEVLTNVT-GAISECVRFQSNREQLRQAGGLP 421
            | |..|                  :|.||:......|...| |.|.......:|...||:.|.:|
 Frog   471 L-TSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIP 534

  Fly   422 AMVSLLNSSHAPL------------------LENLAKG----LKECAEDPDSMRILEDLDAVRLI 464
            .:|.||..:|...                  :|.:.:|    |...|.|..:..::..|:.:.|.
 Frog   535 RLVQLLVRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLF 599

  Fly   465 WSLLKNPTTRVQAHAAYAICPCVRNANDSAELVRSLVGAMELVVGLLKSKDIMVLSAVCAAIATI 529
            ..||.:|...:|..||..:|...:: .::||.:.: .||...:..||.|::..|.:...|.:..:
 Frog   600 VQLLYSPIENIQRVAAGVLCELAQD-KEAAEAIEA-EGATAPLTELLHSRNEGVATYAAAVLFRM 662

  Fly   530 AQDQTNLAILTDLKVIYKLADLVQTTDDLLR 560
            ::|:..         .||....|:.|..|.|
 Frog   663 SEDKPQ---------DYKKRLSVELTSSLFR 684

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
guduNP_609111.1 armadillo repeat 105..134 CDD:293788 4/16 (25%)
armadillo repeat 144..180 CDD:293788 11/36 (31%)
Arm_3 214..557 CDD:330530 82/445 (18%)
armadillo repeat 245..275 CDD:293788 10/29 (34%)
armadillo repeat 286..318 CDD:293788 6/31 (19%)
armadillo repeat 328..362 CDD:293788 8/33 (24%)
armadillo repeat 411..447 CDD:293788 11/57 (19%)
armadillo repeat 453..484 CDD:293788 8/30 (27%)
armadillo repeat 494..526 CDD:293788 9/31 (29%)
ARM 614..652 CDD:214547
armadillo repeat 619..652 CDD:293788
ctnnb1NP_001016958.1 armadillo repeat 153..178 CDD:293788
armadillo repeat 188..221 CDD:293788 4/16 (25%)
PLN03200 216..>661 CDD:215629 102/505 (20%)
armadillo repeat 230..262 CDD:293788 10/31 (32%)
ARM 230..262 CDD:214547 10/31 (32%)
armadillo repeat 270..306 CDD:293788 10/35 (29%)
armadillo repeat 312..347 CDD:293788 5/34 (15%)
ARM 350..390 CDD:214547 3/39 (8%)
armadillo repeat 354..389 CDD:293788 3/34 (9%)
armadillo repeat 402..427 CDD:293788 10/47 (21%)
armadillo repeat 435..473 CDD:293788 13/70 (19%)
armadillo repeat 482..517 CDD:293788 7/34 (21%)
armadillo repeat 524..582 CDD:293788 11/57 (19%)
Arm 583..622 CDD:366143 10/38 (26%)
armadillo repeat 587..621 CDD:293788 9/33 (27%)
armadillo repeat 629..662 CDD:293788 8/33 (24%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R2332
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.030

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