DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gudu and Rsph14

DIOPT Version :9

Sequence 1:	NP_609111.1	Gene:	gudu / 34014	FlyBaseID:	FBgn0031905	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	XP_006256402.1	Gene:	Rsph14 / 365552	RGDID:	1305601	Length:	341	Species:	Rattus norvegicus

Alignment Length:	325	Identity:	69/325 - (21%)
Similarity:	113/325 - (34%)	Gaps:	65/325 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   208 LKTPRDQLSPDDLESLDMTRAGARALFTLADSKHNMEQMRKS---GIVPLMAQLLKS------CH 263
            |:...::|..:||    :||  .:|:..|.|..|:.|.:.::   |.:..:..|||.      ..
  Rat    28 LRKLNEELQSEDL----LTR--QKAVMALCDLMHDPEYVYEAINIGCLESLKALLKDDDNLVRIK 86

  Fly   264 IDVVIPIMGT-----------------------------------VRKCSSEPKFQLAITTEGMI 293
            ...|:.||.|                                   .:..:..|:....|.|.|:|
  Rat    87 TTEVLYIMATHNVGRVGFLKHDIILALSRLLSDHQTLCRENLHQAYKHLAQLPEGAQGIVTSGLI 151

  Fly   294 PDIVSHLSSENTELKMEGSTAIYKCAFDGTTRDLVREAGGLEPLVTIIKDKNVRENKPLLRGATG 358
            ..:|..|..|...::......:..|..:..|..|..:|      |...|:|....|..:...|..
  Rat   152 SFLVRKLQKEELHIQEIILDTLALCLQEDATEALNSQA------VPCFKEKLFSGNPQIRSKAAR 210

  Fly   359 AIWMCAVTDANVKVLDQLRTVNHLVALLNDECDEVLTNVTGAISECVRFQSNREQLRQAGGLPAM 423
            |:...::.....:.:.|...:..||.||:|..:||..|..||:.........:.....|..:..:
  Rat   211 ALIAISIPLDGKRQVWQNEVIPILVDLLSDTDEEVKANAAGALMHATVTTEGKYAALDANAIDPL 275

  Fly   424 VSLLNSSHAPLLE---NLAKGLKECAEDPDSMRILEDLDAVRLIWSLL--KNPTTRVQAHAAYAI 483
            :.||.|  .|..:   |..|.|...||.|:..::|  |..|.....||  ||...|..|..|..:
  Rat   276 LELLCS--IPTTKVCLNATKALTMLAEAPEGRKLL--LPRVPTFRYLLTHKNEAIRRAAEVAIKV 336

Fly 484 483
Rat 337 336

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gudu	NP_609111.1	armadillo repeat	105..134	CDD:293788
		armadillo repeat	144..180	CDD:293788
		Arm_3	214..557	CDD:330530	68/319 (21%)
		armadillo repeat	245..275	CDD:293788	8/73 (11%)
		armadillo repeat	286..318	CDD:293788	7/31 (23%)
		armadillo repeat	328..362	CDD:293788	7/33 (21%)
		armadillo repeat	411..447	CDD:293788	8/38 (21%)
		armadillo repeat	453..484	CDD:293788	10/33 (30%)
		armadillo repeat	494..526	CDD:293788
		ARM	614..652	CDD:214547
		armadillo repeat	619..652	CDD:293788
Rsph14	XP_006256402.1	HEAT repeat	27..55	CDD:293787	9/32 (28%)
		HEAT repeat	72..93	CDD:293787	4/20 (20%)
		HEAT repeat	109..137	CDD:293787	0/27 (0%)
		ARM	143..253	CDD:237987	27/115 (23%)
		HEAT repeat	151..175	CDD:293787	4/23 (17%)
		armadillo repeat	190..215	CDD:293788	6/24 (25%)
		armadillo repeat	222..257	CDD:293788	11/34 (32%)
		ARM	224..337	CDD:237987	32/117 (27%)
		armadillo repeat	263..295	CDD:293788	7/33 (21%)
		HEAT repeat	308..334	CDD:293787	9/27 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0167
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900