Protein Alignment ninaC and MYO3

DIOPT Version :10

• Sequence 1: NP_523503.2
• Gene: ninaC / 34012
• FlyBaseID: FBgn0002938
• Length: 1501
• Species: Drosophila melanogaster
• Sequence 2: NP_012793.2
• Gene: MYO3 / 853729
• SGDID: S000001612
• Length: 1272
• Species: Saccharomyces cerevisiae
• Alignment Length: 1241
• Identity: 290/1241 - (23%)
• Similarity: 510/1241 - (41%)
• Gaps: 216/1241 - (17%)

  Fly   293 RSDIAEMLELSRDVKTLYKEPELFVDRGYVKRFD-EKPEKMYPEDLAALENPVDENIIESLRHRI 356
            |.|:.|..:.|..:|.              ..|| .|.:::...||..|....||:|.|:|:.|.
Yeast    10 RKDVKEPKKRSAKIKK--------------ATFDANKKKEVGISDLTLLSKISDESINENLKKRF 60

  Fly   357 LMGESYSFIGDILLSLNSNEIKQEFPQEFHAKYRFKSRSENQPHIFSVADIAYQDMLHHKEPQHI 421
            ..|..|::||.:|:|:|.......:.......|:.|:|.|..||:|::|:..|.::..:.|.|.:
Yeast    61 KNGIIYTYIGHVLISVNPFRDLGIYTNAVLESYKGKNRLEVPPHVFAIAESMYYNLKSYNENQCV 125

  Fly   422 VLSGESYSGKSTNARLLIKHLCYLGDGNRGATGRVESSIKAILMLVN----AGTPVNNDSTRCVL 482
            ::||||.:||:..|:.:::::....:.:..:.|:::..:.|...|:.    |.|..||:|:|...
Yeast   126 IISGESGAGKTEAAKRIMQYIAAASNSHSESIGKIKDMVLATNPLLESFGCAKTLRNNNSSRHGK 190

  Fly   483 QYCLTFGKTGKMSGAVFNMYMLEKLRVATTDGTQHNFHIFYYF----YDFINQQNQLKEYNLKAD 543
            ...:.|....:........|:|||.||......:.||||||.|    .|...|.     :.::..
Yeast   191 YLEIKFNSQFEPCAGNITNYLLEKQRVVGQIKNERNFHIFYQFTKGASDTYKQM-----FGVQMP 250

  Fly   544 RNYRYLRVPPEVPPSKLKYRRDDPEGNVERYREFENILRDIDFNHKQLETVRKVLAAILNIGNIR 608
            ..|.|...........:    ||    |:.|......:|.|....::.:.:.::|||||.||||.
Yeast   251 EQYIYTAAAGCTTADTI----DD----VKDYEGTLEAMRTIGLVQEEQDQIFRMLAAILWIGNIS 307

  Fly   609 FRQNGK-YAEVENTDIVSRIAELLRVDEKKFMWSLTNFIM-----VKGGIAERRQYTTEEARDAR 667
            |.:|.: .|:|.:|.:...:|.||:||....:..|...||     :|.|..........:|...|
Yeast   308 FIENEEGNAQVGDTSVTDFVAYLLQVDASLLVKCLVERIMQTSHGMKRGSVYHVPLNPVQATAVR 372

  Fly   668 DAVASTLYSRLVDFIINRINMNM-SFPRAVFGDTNAIIIHDMFGFECFNRNGLEQLMINTLNEQM 731
            ||:|..:|:.|.|:|::|:|::: :||    |...:|.|.|::|||.|..|..||:.||.:||::
Yeast   373 DALAKAIYNNLFDWIVDRVNVSLQAFP----GADKSIGILDIYGFEIFEHNSFEQICINYVNEKL 433

  Fly   732 QYHYNQRIFISEMLEMEAEDIDTINLNFYDNKTALDNLLTK-PDGLFYIIDD------ASRSCQD 789
            |..:.|....:|....|.|.|....:.::|||...|.:..| |.|:...::|      |..:..|
Yeast   434 QQIFIQLTLKAEQETYEREKIKWTPIKYFDNKVVCDLIEAKNPPGILAAMNDSIATAHADSNAAD 498

  Fly   790 QDLIMDRVSEKHSQFVKKHTATEISVAHYTGRIIYDTRAFTDINRDFVPPEMIETFRSSLDESIM 854
            | ....|::..:|....:..|.:..:.||.|.:.||....||.|:|.:..::||...::.:..:.
Yeast   499 Q-AFAQRLNLFNSNPYFELRANKFVIKHYAGDVTYDINGITDKNKDQLQKDLIELIGTTTNTFLS 562

  Fly   855 LMFTNQLTKAGNLTMPFEAVQHKDESERKSYALNTLSAGCISQVNNLRTLAANFRFTCLTLLKML 919
            .:|.:.:.|               :|:|:.   .|.....|...|.              |::.|
Yeast   563 TIFPDDVDK---------------DSKRRP---PTAGDKIIKSANE--------------LVETL 595

  Fly   920 SQNANLGVHFVRCIRADLEYKPRSFHSDVVQQQMKALGVLDTVIARQKGFSSRLPFDEFLRRYQF 984
            |:   ....::|.|:.:....|..:....|..|:|.||:.:.|..|:.||:.|..|::|:.|:..
Yeast   596 SK---AEPSYIRTIKPNQTKSPNDYDDHQVLHQVKYLGLQENVRIRRAGFAYRQTFEKFVERFYL 657

  Fly   985 LAFDFDEPVEMTKDNCRL----LFLRLKM---EGWALGKTKVFLRYYNDEFLARLYELQVK---- 1038
            |:.|.....:.|.|...|    |.||..|   :.:.||.|.||::  ..|.|..|.:::.|
Yeast   658 LSPDCSYAGDYTWDGDTLEAVKLILRDAMIPEKEFQLGVTSVFIK--TPESLFALEDMRDKYWYN 720

  Fly  1039 KVIKVQSMMRALLARKRVKGGKVFKLGKKGPEHHDVAASKIQKAFRGFRDRVRLPPLVNEKSGQL 1103
            ...::|...|..|.| |:.                 ||.|||:..|            .:|.|..
Yeast   721 MAARIQRAWRRFLQR-RID-----------------AAIKIQRTIR------------EKKGGNK 755

  Fly  1104 NENTADF-IRPFAKKWREKSIFQVLLHYRAARFQDFV--NLSQQVHIYNQRMVAGLNKCTRAVPF 1165
            .....|: .:..|.|...:|:  .||.|||. ..|::  |.|:....|.:|.|...:|...::..
Yeast   756 YVKLRDYGTKLLAGKKERRSM--SLLGYRAF-MGDYLSCNESKTKGSYIRRQVGIKDKVVFSIKG 817

  Fly  1166 ERINMREVNSSQLGPLPVPIKKMPFRLDQIPF-------------YDTQYMVDPANSISRQAFPN 1217
            |.::.:...|:|      .:||: |.|.:..|             |...|.:| ...|.:.:..|
Yeast   818 ECLHSKFGRSAQ------RLKKV-FILTKKTFYIIGQTREQNAMKYTQDYKID-VGKIKQVSLTN 874

  Fly  1218 QLLTQHMEDDEPWDSPLQRNPSMTSCALTYNAYKKEQACQTNWDRMGESDNIYNQG----YFRDP 1278
                  ::||  |...:..| |..|..|....:|.|  ..|...::.|...| ..|    |.:.|
Yeast   875 ------LQDD--WMGVILVN-STQSDPLINTPFKTE--LMTRLKKLNEKIMI-KVGPTIEYHKQP 927

  Fly  1279 QQLR--RNQMQMNMNAYNNAYNSYNSNYNNQNWGVHRSGSRRNSLKGYAAPPPPP-----PPMPS 1336
            .:|.  |:::..:...|.:.|.| ::.|..:.   |.:.|:.|.      .|..|     .|:.|
Yeast   928 NKLHTVRSKISDSAPKYGDIYKS-STIYVRRG---HPANSKSNK------KPKNPGGLSGKPIKS 982

  Fly  1337 ------SNYYRNNPNQQQRNYQQRSSYPPSDPVRELQNMARNEGDNSEDPPFNFKAMLRKTNYPR 1395
                  |.:...:.::..|:..::...|...||..| ::|......:.:|..:....::.:..|.
Yeast   983 KKSKHKSTHKHTHSHRSHRDAAKKQPLPSQKPVNPL-SLAATAAQAAYNPKPDKTVPIKSSAIPA 1046

  Fly  1396 GSETNTYDFNNRRGSDSGDQHTFQPPKLRSTGRRYQDDEGYNSSSGNYGVSR--KFGQQQRAPTL 1458
            ...::              :|:.:|........:.......:||:....||.  ..|.::....|
Yeast  1047 AKVSS--------------KHSSKPSSKEKVAVKKASSSHKSSSAKQNQVSMPPSKGVEKNKEPL 1097

  Fly  1459 RQSPAS 1464
            :::.|:
Yeast  1098 KETTAT 1103

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ninaC	NP_523503.2	STKc_myosinIII_N_like	9..282	CDD:270785
		MYSc_Myo21	346..1022	CDD:276848	186/704 (26%)
MYO3	NP_012793.2	COG5022	1..1258	CDD:227355	290/1241 (23%)