Protein Alignment ninaC and MYO4

DIOPT Version :10

• Sequence 1: NP_523503.2
• Gene: ninaC / 34012
• FlyBaseID: FBgn0002938
• Length: 1501
• Species: Drosophila melanogaster
• Sequence 2: NP_009373.1
• Gene: MYO4 / 851204
• SGDID: S000000027
• Length: 1471
• Species: Saccharomyces cerevisiae
• Alignment Length: 1024
• Identity: 257/1024 - (25%)
• Similarity: 452/1024 - (44%)
• Gaps: 192/1024 - (18%)

  Fly   256 NDFISESLE---KNAENRPMMVEMVEHPFLTELIENEDEMRSDIAEMLELSRDVKTLYKEPELFV 317
            |||...:..   |..:...:.:|       |...||:|:                    .|.|.|
Yeast    26 NDFFEGTFHLELKLEDGETVSIE-------TNSFENDDD--------------------HPTLPV 63

  Fly   318 DRGYVKRFDEKPEKMYPEDLAALENPVDENIIESLRHRILMGESYSFIGDILLSLNS-NEIKQEF 381
            .|       ..|.....:||..|....:..::.:::.|.:.|:.|::.|.:|::.|. :::...:
Yeast    64 LR-------NPPILESTDDLTTLSYLNEPAVLHAIKKRYMNGQIYTYSGIVLIAANPFDKVDHLY 121

  Fly   382 PQEFHAKYRFKSRSENQPHIFSVADIAYQDMLHHKEPQHIVLSGESYSGKSTNARLLIKHLCYLG 446
            .:|....|..|.:.|.:||:|::|:.||:.|:|.|..|.:|:||||.:||:.:|:.::::...:.
Yeast   122 SREMIQNYSSKRKDELEPHLFAIAEEAYRFMVHEKANQTVVVSGESGAGKTVSAKYIMRYFASVQ 186

  Fly   447 DGNRGATGRVE-SSIKAILMLV--------NAGTPVNNDSTRCVLQYCLTFGKTGKMSGAVFNMY 502
            :.| ...|.|| |.|::.::..        ||.|..|::|:|......:.|.:...:.|:....|
Yeast   187 ESN-NREGEVEMSQIESQILATNPIMEAFGNAKTTRNDNSSRFGKYLQILFDENTTIRGSKIRTY 250

  Fly   503 MLEKLRVATTDGTQHNFHIFYYFYDFINQQNQLKEYNLKADRNYRYLRV--PPEVPPSKLKYRRD 565
            :|||.|:.....|:.|:||||...:.:.:..: :|.:|.:.::|.|...  .|.:
Yeast   251 LLEKSRLVYQPETERNYHIFYQILEGLPEPVK-QELHLSSPKDYHYTNQGGQPNI---------- 304

  Fly   566 DPEGNVERYREFE---NILRDIDFNHKQLETVRKVLAAILNIGNIRFRQNGKYAEVENTDIVSRI 627
               ..::..||::   :.|..:..||:....:.|:||.:|:||||..:.....|.:.:.:...:|
Yeast   305 ---AGIDEAREYKITTDALSLVGINHETQLGIFKILAGLLHIGNIEMKMTRNDASLSSEEQNLQI 366

  Fly   628 A-ELLRVDEKKF-MWSLTNFIMVKGGIAERRQ-----YTTEEARDARDAVASTLYSRLVDFIINR 685
            | |||.:|...| .|      :||..|..|.:     ....:|..|||:||..:||.|.|::::.
Yeast   367 ACELLGIDPFNFAKW------IVKKQIVTRSEKIVTNLNYNQALIARDSVAKFIYSTLFDWLVDN 425

  Fly   686 INMNMSFPRA-----VFGDTNAIIIHDMFGFECFNRNGLEQLMINTLNEQMQYHYNQRIFISEML 745
            ||..:..|..     ||   :.|.|.|::|||.|.:|..||..||..||::|..:||.:|..|..
Yeast   426 INKTLYDPELDQQDHVF---SFIGILDIYGFEHFEKNSFEQFCINYANEKLQQEFNQHVFKLEQE 487

  Fly   746 EMEAEDIDTINLNFYDNKTALDNLLTKPDGLFYIIDDASR--SCQDQDLIMDRVSEKHSQFVK-- 806
            |...|:|:...:.|.||:..:| |:....|:..::|:.||  |..|:..    .|:.:|.|.|
Yeast   488 EYVKEEIEWSFIEFSDNQPCID-LIENKLGILSLLDEESRLPSGSDESW----ASKLYSAFNKPP 547

  Fly   807 --------KHTATEISVAHYTGRIIYDTRAFTDINRDFVPPEMIETFRSSLDESIMLMFTNQLTK 863
                    :...|:..|:||...:.|:...|.:.|||.|....::.|:::         ||.:.|
Yeast   548 SNEVFSKPRFGQTKFIVSHYAVDVEYEVEGFIEKNRDSVSLGHLDVFKAT---------TNPIFK 603

  Fly   864 --AGNLTMPFEAVQHKDESERKSYALNTLSAGCISQVNNLRTLAANFRFTCLTLLKMLSQNANLG 926
              ..|..:..:....:..:|:|......||       ....||.:.|:.:...|:.:::   :..
Yeast   604 QILDNRELRSDDAPEEQNTEKKIMIPARLS-------QKKPTLGSMFKKSLGELMAIIN---STN 658

  Fly   927 VHFVRCIRADLEYKPRSFHSDVVQQQMKALGVLDTVIARQKGFSSRLPFDEFLRRYQFLAFDF-- 989
            ||::|||:.:.|.||..|.:.:|..|::|.|||:|:.....||.||..||||::|| ||..|:
Yeast   659 VHYIRCIKPNSEKKPWEFDNLMVLSQLRACGVLETIRISCAGFPSRWTFDEFVQRY-FLLTDYSL 722

  Fly   990 --------DEPVEMTKDNCRLLFLRLKMEG--WALGKTKVFLRYYNDEFL--------------- 1029
                    |.|.|...:.|:.:......:.  :.:|.||:|.:.....||
Yeast   723 WSGILYNPDLPKEAIVNFCQSILDATISDSAKYQIGNTKIFFKAGMLAFLEKLRTNKMNEICIII 787

  Fly  1030 -----ARLYELQ----VKKVIKVQSMMRALLARKRVK-----------GGKVFKLGKKGPEHHDV 1074
                 ||.|.||    ::.:.|.||.:|:||.|.||.           ...:..|.|:  |::..
Yeast   788 QKKIRARYYRLQYLQTMESIKKCQSQIRSLLVRTRVDHELKTRAAILLQTNIRALWKR--EYYRA 850

  Fly  1075 AASKIQKAFRGFRDRVRLPPLVNEKSGQLNENTADFIRPFAKKWREKSIFQVL-----LHYRAAR 1134
            |..:|.|.....:.::.|.. ||.|...:   .|..|:.:.:.:..|:.::.|     |...|.|
Yeast   851 AIGQIIKLQCTCKRKLILDS-VNRKFMLM---AAVIIQSYIRSYGHKTDYRTLKRSSILVQSAMR 911

  Fly  1135 FQ----DFVNLSQQVHIYNQRMVAGLNKCTRAVPFER---INMREVNSS 1176
            .|    .::.|.::|...|.|...|:.....|:.|:.   :|:..:|.|
Yeast   912 MQLARRRYIVLQKEVEERNIRASYGIGLLEEAIEFKNSFILNLEMLNDS 960

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ninaC	NP_523503.2	STKc_myosinIII_N_like	9..282	CDD:270785	5/28 (18%)
		MYSc_Myo21	346..1022	CDD:276848	196/728 (27%)
MYO4	NP_009373.1	COG5022	2..1471	CDD:227355	257/1024 (25%)