Protein Alignment ninaC and myo16

DIOPT Version :10

• Sequence 1: NP_523503.2
• Gene: ninaC / 34012
• FlyBaseID: FBgn0002938
• Length: 1501
• Species: Drosophila melanogaster
• Sequence 2: XP_001920958.3
• Gene: myo16 / 563752
• ZFINID: ZDB-GENE-070912-470
• Length: 1910
• Species: Danio rerio
• Alignment Length: 1807
• Identity: 406/1807 - (22%)
• Similarity: 665/1807 - (36%)
• Gaps: 529/1807 - (29%)

  Fly    89 DEIWFVMEYCAGGTAVDM--------VNKLLK-------LDRRMREEHIAYI-IRETCRAAIELN 137
            :::|..:.........||        ||.||:       ||.........|| ||......::::
Zfish   145 EDLWTALHVACACDHADMVLLLLLAGVNVLLQDVNGNIPLDYTTEGTETRYILIRHLEENGVDMS 209

  Fly   138 RNH--------VLHRDIRGDNILLTKNGRV-KLCDFGLS-RQVDSTLGKRGTCIGSPCWMAPEVV 192
            ..|        .:..|::.   |::..|.| :..|.|:: ..:.|..|.:            |||
Zfish   210 SVHQMKSQRCFTMMSDVKQ---LVSSGGSVNQQNDDGVTLLHIASASGYK------------EVV 259

  Fly   193 SAMESREPDITVR-ADVWALGITTIELADGKPPFADMHPTRAMFQIIRN-PPPTLMRPTNWSQQI 255
            |.:.....|:.|. :..|    |.:.||      |....|..:.|:::: ..|||:   |.:|
Zfish   260 SVLLENGADVLVSDSSYW----TPLHLA------AKYGQTHIVSQLLKHKADPTLL---NCNQ-- 309

  Fly   256 NDFISESLEKNAENRPMMVEMVEHPFLTELI-------------------ENED---EMRSD--- 295
                         ::|..:...||  :.|::                   ::||   |...|
Zfish   310 -------------DKPSDIAATEH--IAEMLLRAEEFWVQRQRDPSASPPQSEDHSAEANQDDNL 359

  Fly   296 ----IAEM-LELSRDVKTLYKEPELFVDRG----YVKRFDEKPEKMYP----------------- 334
                :|.| |.:||....|.|| .:|.|.|    .....|...:..||
Zfish   360 PVKKLATMALPISRRDSLLEKE-AMFRDSGGALTQQASLDNGLDGSYPSAAGKLEQVKLMPPAPN 423

  Fly   335 EDLAALENPVDENIIESLRHRILMGESYSFIGDILLSLN--------SNEIKQEFPQEFHAKYRF 391
            :|||:|....|.:::..::.|....:.|::||.|||.:|        ||.:.|     .:.....
Zfish   424 DDLASLSELTDSSLLYEMQKRFANDQIYTYIGHILLLINPYKDLPIYSNLVSQ-----LYLSSSG 483

  Fly   392 KSRSENQPHIFSVADIAYQDMLHHKEPQHIVLSGESYSGKSTNARLLIKHLCYLGDGNRGATGRV 456
            :..|...|||||.|:.|:..|...:.||..::||||.||||...:.::|||.........|   :
Zfish   484 RLCSSLPPHIFSSAERAFHMMFQERRPQCFIISGESGSGKSVACKHILKHLAARSSPKGFA---L 545

  Fly   457 ESSIKAILMLV----NAGTPVNNDSTRCV----LQYCLTFGKTGKMSGAVFNMYMLEKLRVATTD 513
            |..:|.:.:::    :|.|.:|...:|.:    |||| ...|| .:.|.::. |||||.||....
Zfish   546 EPRMKHVNVILEAFGHAKTQMNTSGSRFIKLISLQYC-DKRKT-LLRGRLYT-YMLEKSRVICMP 607

  Fly   514 GTQHNFHIFYYFYDFIN--QQNQLKEYNLKADRNYRYLRVPPEVP--PSKLKYRRDDPEGNVERY 574
            ..|.||:|||...:.::  :::||...|:.|.|... ...|.|.|  .|.....|       |:.
Zfish   608 PHQQNFNIFYLMAEGLSAEEKSQLYLNNVLAHRCLN-TAAPGESPAVASACPQSR-------EKL 664

  Fly   575 REFENILRDIDFNHKQLETVRKVLAAILNIGNIRFR--QNGKYAEVENTDIVSRIAELLRVDEKK 637
            ...:..||.:.||..::|.|..:::|:|::|::||.  .:...|.|.:..::.|:|.:|:|..:.
Zfish   665 LALKQALRALGFNKLEVENVFVLISALLHLGDLRFTALTDADTAFVSDLQLLDRVAGMLQVSSED 729

  Fly   638 FMWSLTNFIM-VKGGIAERRQYTTEEARDARDAVASTLYSRLVDFIINRINMNMSFPRAVFGD-T 700
            ...:||:.:. .||.:..|| :|.|.:...||.:...||.||...::|.||..:.......|| .
Zfish   730 LSSALTSDVQCFKGDVITRR-HTVEMSNHHRDLLTKALYGRLFSLLVNNINFYLQGHEETTGDPA 793

  Fly   701 NAIIIHDMFGFECFNRNGLEQLMINTLNEQMQYHYNQRIFISEMLEMEAEDIDTINLNFYDNKTA 765
            ..|.|.|:||||.|.||..|||.||.:||::.....:.:|..|..|...|.:....|....::||
Zfish   794 LEISILDIFGFEEFQRNAYEQLCINMVNERIHQFTAEVLFQQEQHECLQEGVAMETLRSLGSQTA 858

  Fly   766 -LDNLLTKPDGLFYIIDDASRSCQDQDLIM-------------DRVS----EKHSQFVKKHTATE 812
             ||....||.|:..|||:.|:|.:..::.:             |.||    :.:.....|.....
Zfish   859 VLDFFFQKPQGVLCIIDEESQSLRPCEVNLYKRLQIQLDSSATDAVSLTTKDGNGNPPPKDQGPS 923

  Fly   813 ISVAHYTGRIIYDTRAFTDINRDFVPPEMIETFRSSLDESIMLMFTNQLTKAGNL---------- 867
            .:|.|:.|::.||.....|.|:|.:|..::...::|.:..|..||..:||:.|:|
Zfish   924 FTVTHFAGKMTYDLTGSLDRNKDVLPQNILFVMKTSENVLIHQMFQCKLTQTGSLVPQHQRMKLR 988

  Fly   868 ----TMPFEAVQHKDESERKSYA-LNTL--SAGCISQVNNLR-----TLAANFRFTCLTLLKMLS 920
                |:..::.......:.|.|. ||.|  ..|..|.:..|.     |:|...:   .:|.::.|
Zfish   989 GPKGTLINKSTTLNPARDAKKYVELNKLLKKKGASSFLQRLERCGPITVAVQLK---NSLCEITS 1050

  Fly   921 QNANLGVHFVRCIRADLEYKPRSFHSDVVQQQMKALGVLDTVIARQKGFSSRLPFDEFLRRYQFL 985
            :..:...||::|:|.:...||..|.|..|..|::.:|||:.|...:.|:..||.|..||.||:.|
Zfish  1051 KLQSCTPHFIQCVRPNNASKPDVFDSFHVSSQLQYVGVLEMVRMIRYGYPVRLSFSSFLSRYREL 1115

  Fly   986 AFDF--DEPVEMTKDNCRLLFLRLKMEGWALGKTKVFLRYYN-DEFLARLYELQVKKVIKVQSMM 1047
            ....  |.....|::.||.:.|..|::||.:|.:||||||:. |....|.::|. :|:|..|.:|
Zfish  1116 VDTIITDRKKATTEEKCRHILLHCKLQGWQMGNSKVFLRYWQADHLNDRCHQLH-RKIIICQKVM 1179

  Fly  1048 RALLARKRVKGGKVFKLGKKGPEHHDVA---------------------ASKIQKAFRGFRDRVR 1091
            |..|||::|:.    :|..:..|..:|.                     |:.|.:.....|..:.
Zfish  1180 RGWLARQQVRR----RLTSRKQELCNVQRFLQGAEDLGLRTYDNLVIQNAADIARENDRLRGHIS 1240

  Fly  1092 LPPL----------------VNEKSGQLNENTADFIRPFAKKWREKSIFQVLLHYRAARFQDFVN 1140
            .|||                |.||||:.|:        .|.:...:.|    .|:|::.....:.
Zfish  1241 APPLGERPEPVGKEEDSPKRVVEKSGRGND--------VANRGGNRPI----RHFRSSSVPLPLV 1293

  Fly  1141 LSQQVHIYNQRMVAGLNKCTRAVPF--ERINMREVNSSQLGPLPVPIKKMPFRLDQIPFYD---- 1199
            :...||   ..:.|.:....:..|.  :..|...::|.:..|.|.|.:....||.  ..|:
Zfish  1294 MDSLVH---SSIGASIKAALQPTPHSTDEGNGGSLSSPRKQPPPKPKRDPNTRLS--ASYEAVSA 1353

  Fly  1200 -----------------------TQYMVDPANSISR-------------------QAFPNQLLTQ 1222
                                   ||  :.|::|:::                   :..||..||.
Zfish  1354 GLSIAPKDSPAEGQASPSGSPPNTQ--LSPSDSLAKPRPHSDDYSTMKKIPPPKPKRSPNTKLTG 1416

  Fly  1223 HMED------DEPWDSPL-------------QRNPSM----TSCALTYNAYKKEQA--------- 1255
            ..|:      ..|.|..|             ||..|.    :|....|....:|..
Zfish  1417 SYEEISVPSPARPTDMKLVSLVRGGHCLGLIQRAASADGPHSSVLSLYPCQDEEDVYIEMVGASR 1481

  Fly  1256 ----CQTNWDRMGESDNIYNQ-GYFRDPQ------------------------------------ 1279
                ..|:....||:  :|.: .||.:.:
Zfish  1482 ALSLADTHSPEPGEA--VYEEMKYFPNDEIVSTPVVKPEAVNPTPLPAPVLEIKRPVTLIEQSGT 1544

  Fly  1280 ----QLRRNQMQMNMNA-YNNAYN-----------------------------------SYNSNY 1304
                |..::.|..::.| :.|...                                   ..|.||
Zfish  1545 LGGKQQGKDGMPCDIPAPFPNLLPHRPPLLVFPPSPVTCSPASDESPLTPLEVKKLPVFETNLNY 1609

  Fly  1305 NNQNWGVHRS----GSRRNSLKGYA-----------APPPPPPP-------MPSSNYYRNNPNQQ 1347
            ::|:.|...|    ..|.:|....:           .|||||||       .|.|::    |...
Zfish  1610 SSQDGGSPLSPQYTRQRADSSPSLSILMPDKSTPPLTPPPPPPPAVLPPPYRPPSHF----PFPP 1670

  Fly  1348 QRNY----------------------------QQRSSYPPSDPVRELQNMARNEGDNSEDP---- 1380
            :.|:                            ...||.||..||:..:...|.....|..|
Zfish  1671 EPNFLALTRAASVASTESPKVSHKMGHGLAETPPSSSKPPFSPVKTSRPEPRRAHSCSSSPLLFN 1735

  Fly  1381 PFNFKAMLRKTNYPRGSETNTYDFNNRRGSDSGDQHTFQPPKLR--STGRRYQDDEGYNSSSGNY 1443
            |.|.:.:....:     |.||. |::.|.            .||  :|||:.: |.|.::|:.|.
Zfish  1736 PANGRPLTSPLD-----ELNTI-FSSGRS------------LLRKSTTGRKIR-DSGLSNSNINL 1781

  Fly  1444 GVSRKFGQQQRAPTLRQSPASVGRSFEDSNARSFEEAGSYVEEEIAPGITLS 1495
            .     |::.      |.|.|.....:|.||.:.....|.....|..|..:|
Zfish  1782 P-----GRED------QGPISPSAQLQDKNANNHTSPNSSNPAPIENGNQIS 1822

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ninaC	NP_523503.2	STKc_myosinIII_N_like	9..282	CDD:270785	43/220 (20%)
		MYSc_Myo21	346..1022	CDD:276848	210/741 (28%)
myo16	XP_001920958.3	ANKYR	83..330	CDD:440430	44/229 (19%)
		ANK repeat	113..144	CDD:293786
		ANK repeat	146..207	CDD:293786	13/60 (22%)
		ANK repeat	242..273	CDD:293786	9/42 (21%)
		ANK repeat	275..306	CDD:293786	10/43 (23%)
		Motor_domain	435..1154	CDD:473979	210/741 (28%)
		NYAP_N	1242..1672	CDD:464717	71/454 (16%)
		NYAP_C	1726..>1772	CDD:464724	14/64 (22%)