Protein Alignment ninaC and myo9b

DIOPT Version :9

• Sequence 1: NP_523503.2
• Gene: ninaC / 34012
• FlyBaseID: FBgn0002938
• Length: 1501
• Species: Drosophila melanogaster
• Sequence 2: XP_005171391.1
• Gene: myo9b / 560956
• ZFINID: ZDB-GENE-030131-938
• Length: 1974
• Species: Danio rerio
• Alignment Length: 1587
• Identity: 352/1587 - (22%)
• Similarity: 603/1587 - (37%)
• Gaps: 457/1587 - (28%)

  Fly   156 NGRVKLC--DFGLSRQVDSTLGKRGTCIGSPCWMAPEVVSAMESREPDITVRADVWALGITTIEL 218
            ||:..:|  :...:.|:...|..:.   |..|.:          |.|.....|.|....:||:.|
Zfish     5 NGKATICQDESVCALQIYPRLSAKP---GQDCIL----------RVPKEATAATVIKTALTTLGL 56

  Fly   219 ADGKPPFADMHPTRAMFQIIRNPPPTLMRPTNWSQQINDFISESLEKNAENRPMM-------VEM 276
            ...||                          :...::.::..|.....|.:.|:.       ...
Zfish    57 DTSKP--------------------------HVLVEVQEYGGEEWVLQASDLPVQRVLLWPRKAQ 95

  Fly   277 VEHP------FLTELIENEDEMRSDIAEMLELSRDVKTLYKEPELFVDRGYVKRFDEKPEKMYPE 335
            ::||      |..:....:..|..||  |..:.|:     |..:..|.||:|   .::|::.  :
Zfish    96 LKHPQSDGYFFALQEGSYDRSMHYDI--MSSVRRE-----KVAQGLVTRGFV---SQQPQEY--D 148

  Fly   336 DLAALENPVDENIIESLRHRILMGESYSFIGDILLSLNSNEIKQEFPQEFHAKYRFKSRSENQPH 400
            ||..|.:..:|:|:|:||||....:.|:|..:||:::|..:....:...:...|...:..:.:||
Zfish   149 DLCNLPDLTEESILETLRHRFHKQKIYTFASNILIAVNPFKFLPIYNPRYVKMYENHTLGKLEPH 213

  Fly   401 IFSVADIAYQDMLHHKEPQHIVLSGESYSGKSTNARLLIKHLCYLGDGNRGATGRVESSI----K 461
            :|::||.|:..|::.:..|.||:||||.|||:.:...||.  |......:|.|..||.:|    .
Zfish   214 VFAIADAAFHTMMNKRVNQCIVISGESGSGKTQSTNFLIH--CLTALSQKGYTSGVERTILGAGP 276

  Fly   462 AILMLVNAGTPVNNDSTRCVLQYCLTFGK--------TGKMSGAVFNMYMLEKLRVATTDGTQHN 518
            .:....||.|..||:|:|        |||        :|.:.|||...|:|||.|:.:...|:.|
Zfish   277 VLEAFGNAKTAYNNNSSR--------FGKFIQVNYLESGVVRGAVVEKYLLEKCRLVSRGKTERN 333

  Fly   519 FHIFYYFYDFINQQNQLKEYNLKADRNYRYLRVPPEVPPSKLKYRRDDPEGNVERYREFENILRD 583
            :|:|||.....:::.: .|:.|....:|.||:  .|:|.|      :|.......:|.....:..
Zfish   334 YHVFYYLLIGASEEER-DEFKLLQPNDYHYLK--EEMPIS------EDQAEMTHEFRRLHQAMEM 389

  Fly   584 IDFNHKQLETVRKVLAAILNIGNIRFRQN--GKYAEVENTDIVSRIAELLRVDEKKFMWSLTNFI 646
            :.|.....:.:..||:|||.:||:.::..  |:..:|....::|.:::||:|..:..:.:||...
Zfish   390 VGFLPPTKKQIFSVLSAILYLGNVTYKPKDVGEGLKVGPDHVLSALSDLLKVKVELLVEALTTRK 454

  Fly   647 MVKGGIAERRQYTTEEARDARDAVASTLYSRLVDFIINRIN--------MNMSFPRAVFGDTNAI 703
            .:.........|:..||..|||::|.:|||.|.|:|:.|||        :..|.|....|
Zfish   455 AMTANDKLILPYSLNEAITARDSMAKSLYSALFDWIVLRINHALLNKRDLEDSVPCLSIG----- 514

  Fly   704 IIHDMFGFECFNRNGLEQLMINTLNEQMQYHYNQRIFISEMLEMEAEDIDTINLNFYDNKTALDN 768
             :.|:||||.|..|..||..||..|||:||:.|||||..|..|..||.|....::|.||...:..
Zfish   515 -VLDIFGFEDFKTNSFEQFCINYANEQLQYYCNQRIFTLEQEEYLAEGITWHTVDFPDNIGCISL 578

  Fly   769 LLTKPDGLFYIIDDASRSCQDQD-LIMDRVSEKHSQ---FVKKHTATEIS-----VAHYTGRIIY 824
            ...||.|||:::|:.|...|..| .::::..::|..   ||:    |.:.     :.|:.|::.|
Zfish   579 FSKKPTGLFFLLDEESNFPQATDSTLLEKFKQQHQDNPFFVQ----TPVREPAFVILHFAGKVKY 639

  Fly   825 DTRAFTDINRDFVPPEMIETFRSS---------------------LDESIMLMFTNQLTKAGNL- 867
            ..:.|.:.|.|.:.|:::...|||                     |..:|..:..  ..|||..
Zfish   640 QIKDFREKNTDHMRPDIVALLRSSECSYLRQLIGANPVAVFRWGILRATIRTLAV--FNKAGRTW 702

  Fly   868 ------------------------TMP-----------------------------FEAVQHKDE 879
                                    |:|                             |...:.|.|
Zfish   703 AEKHPDEIRRYSRRSFGESRRPSPTVPTIQRLKSQSRIDFSFDRSEEDPLEAFEDIFATFESKKE 767

  Fly   880 -------------------------SERK-----------------------SYALNTLSAGCIS 896
                                     |.||                       |::|..:.|  ::
Zfish   768 LHAKVLRSLRQFGVEVPQKLRLSTNSSRKYRLFSQKNRPNKHKQLIPKNLIDSHSLKFIMA--LT 830

  Fly   897 QVNNLR-------------TLAANFRFTCLTLLKMLSQNANLGVHFVRCIRADLEYKPRSFHSDV 948
            |.|.:.             :::|.|:   .:|.|:|.........||||||::.:.:...|...:
Zfish   831 QHNRVTRSLLHLHTKKKPPSISAQFQ---ASLSKLLETLRKAEPFFVRCIRSNGDKREMHFDDAL 892

  Fly   949 VQQQMKALGVLDTVIARQKGFSSRLPFDEFLRRYQFLAFDFDEPVEMTKDNCRLLFLRLKMEG-- 1011
            |.||::..|:|.||..|:.|:.::..|.||:.:::.|   ..:.:...:::...|..::.:.|
Zfish   893 VLQQLRYTGMLQTVRIRRSGYGAKFTFREFIDQFRVL---LPKEISTPQEDITNLLTKMGLPGSS 954

  Fly  1012 WALGKTKVFLRYYNDEFLAR-LYELQVKKVIKVQSMMRALLARKRVKGGKVFKLGKKG------- 1068
            :.:|:|||||:....:.|.. |::..::::|.:|...||.|.||:      :..|:||
Zfish   955 FQIGQTKVFLKESERQILQETLHKEVMRRIIILQRWFRACLMRKQ------YLRGRKGIITIQRS 1013

  Fly  1069 -----PEHHDVAASKIQKAFRGFRDRVR--------------------------LPPLVNEKSGQ 1102
                 ..:...||..||.|:|..|.|..                          ||.|.||....
Zfish  1014 WRYVRETYRCRAAIVIQIAWRKSRQRAEQEKLKAQAFQRDLNKIEEKKPSQPKPLPSLPNESRTA 1078

  Fly  1103 LNENTADFIRPFAKKWREKSIFQVLLHYRAARFQDFVNLSQQVHIYNQRMVAGLNKCTRAVPFER 1167
            .::.| |..||......:..|          ..|....:::|:.:...|    |.:..|.:
Zfish  1079 ESKKT-DEPRPQLNTDTKPKI----------PTQPTPGITKQLSVKEDR----LGRSNRGM---- 1124

  Fly  1168 INMREVNSSQLGPLPVPIKKMPFRLDQIPFYDTQYMVDPANSISRQAFPNQLLTQHMEDDEPWDS 1232
            :..:|.:.|..| ||.|: .:|..:.|..:.|:|:.|    .:.||...|:|    .|..|.|
Zfish  1125 VGNKERHPSPSG-LPRPV-SLPLNMSQSAYNDSQHTV----QLQRQNKSNRL----TEKPEKW-- 1177

  Fly  1233 PLQRNPSMTSCALTYNAYKKEQACQTNWDRMGESDNIYNQ-----GYFRDPQQLRRNQMQMNMNA 1292
                               ||::  ::..|||..|.|..:     |:.:....|..:.:....::
Zfish  1178 -------------------KERS--SDAARMGNIDEIKPRSHEKIGFLKPGISLSLDNVSRMSSS 1221

  Fly  1293 YNNAYNSYNSN---YNNQNWGVH-------RSGSRRNSL-----KGYAAPPPPPPPMPSSNYYRN 1342
            .:::..|.:.|   ..|:....|       |||.:.:.|     ..::.|.||..|..
Zfish  1222 ESDSSASSSRNEVMVENRKRLKHKRRLARPRSGLKVDDLDLSDSAYWSFPLPPISPAA------- 1279

  Fly  1343 NPNQ----------QQRNYQQRSSYP-----PSDPVRELQNMARNEGDNSEDPPFNFKAMLRKTN 1392
             |||          .|.:.:....:|     ||:.|.........:|         |....:|.:
Zfish  1280 -PNQSITQVVVEAVMQSSVESDGCFPFSNRSPSEEVIAPSITPERKG---------FLKFFKKRS 1334

  Fly  1393 YPR-GSETNTYDFNNRRGSDSGDQHTFQPPKLRSTGRRYQDDEGYNSSSGNY-GVSRKFGQQQRA 1455
            .|: |:.|.......:....||: |:..|               ...:||.| |..|.
Zfish  1335 TPQDGTITMVKTLAEKEELASGN-HSNSP---------------RTKNSGTYPGAHRN------- 1376

  Fly  1456 PTLR---------QSPASVGRSFEDSN 1473
            ||::         |..||:.|...|:|
Zfish  1377 PTIKISRATRTQVQWNASLDREITDTN 1403

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ninaC	NP_523503.2	STKc_myosinIII_N_like	9..282	CDD:270785	21/140 (15%)
		S_TKc	16..282	CDD:214567	21/140 (15%)
		MYSc	327..1034	CDD:214580	217/876 (25%)
		MYSc_Myo21	346..1022	CDD:276848	210/844 (25%)
myo9b	XP_005171391.1	UBQ	13..110	CDD:294102	19/135 (14%)
		MYSc	147..974	CDD:214580	215/867 (25%)
		MYSc_Myo9	159..965	CDD:276836	210/844 (25%)
		C1	1529..1577	CDD:237996
		RhoGAP	1593..1778	CDD:295372

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG4229
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810