Protein Alignment ninaC and Myo7b

DIOPT Version :10

• Sequence 1: NP_523503.2
• Gene: ninaC / 34012
• FlyBaseID: FBgn0002938
• Length: 1501
• Species: Drosophila melanogaster
• Sequence 2: NP_001424233.1
• Gene: Myo7b / 498834
• RGDID: 1561153
• Length: 2114
• Species: Rattus norvegicus
• Alignment Length: 1065
• Identity: 249/1065 - (23%)
• Similarity: 450/1065 - (42%)
• Gaps: 156/1065 - (14%)

  Fly   332 MYP------EDLAALENPVDENIIESLRHRILMGESYSFIGDILLSLNSNEIKQEFPQEFHAKYR 390
            |:|      :|:..|.:..:..::.:|..|....:.|::.|.||:::|..::...:..|....|.
  Rat    59 MHPNSAQGVDDMIRLGDLNEAGVVHNLLIRYQQHKIYTYTGSILVAVNPFQMLPLYTLEQVQIYY 123

  Fly   391 FKSRSENQPHIFSVADIAYQDMLHHKEPQHIVLSGESYSGKSTNARLLIKHLCYLGDGNRGATGR 455
            .:...|..||:|::|:..|.:|..:|..|..::||||.:||:...:|:::.|..:...:.....:
  Rat   124 SRHMGELPPHVFAIANSCYFNMKKNKRDQCCIISGESGAGKTETTKLILQFLATVSGQHSWIEQQ 188

  Fly   456 VESSIKAILMLVNAGTPVNNDSTRCVLQYCLTFGKTGKMSGAVFNMYMLEKLRVATTDGTQHNFH 520
            |..:...:....||.|..|::|:|......:.|..:|.:.||....::|||.||......:.|:|
  Rat   189 VLEANPILEAFGNAKTIRNDNSSRFGKYIDIHFNSSGVIEGASIEHFLLEKSRVCRQAAEERNYH 253

  Fly   521 IFYYFY--DFINQQNQLKEYNLKADRNYRYLRVPPEVPPSKLKYRRDDPEGNVERYREFENILRD 583
            |||...  ..:.::|.|   .|.....|.||.:........|...:|        |....:.::.
  Rat   254 IFYCMLMGMSLEEKNML---GLGMPSEYHYLTMGNCTSYEGLSDAKD--------YAHVRSAMKI 307

  Fly   584 IDFNHKQLETVRKVLAAILNIGNIRFRQNGKYAEVENTDIVSRIA-----ELLRVDEKKFMWSLT 643
            :.|:..:...:.|:|||||::||:.| ....:..::::|::...|     :||.|..:.....|.
  Rat   308 LQFSDSENWDISKLLAAILHLGNVGF-MAAVFENLDSSDVMETPAFPFAMKLLEVQHQALRDCLI 371

  Fly   644 NFIMVKGGIAERRQYTTEEARDARDAVASTLYSRLVDFIINRINMNMSFPRAVFGDT--NAIIIH 706
            ...:...|....|.....:|.|.|||....:|..|..:|:.:||..:..|:|.....  .||.:.
  Rat   372 KHTIPILGEFVSRPLNIAQAADRRDAFVKGIYGHLFLWIVKKINAAIFTPQAQDPQNVRRAIGLL 436

  Fly   707 DMFGFECFNRNGLEQLMINTLNEQMQYHYNQRIFISEMLEMEAEDIDTINLNFYDNKTALDNLLT 771
            |:||||.|..|..|||.||..||.:|..:.:.:|..|..|..:|:|....:::.||:..||.|..
  Rat   437 DIFGFENFQNNSFEQLCINFANEHLQQFFVKHVFTMEQEEYLSENITWNYIHYTDNQPILDMLAL 501

  Fly   772 KPDGLFYIIDDASRSCQDQDLIM----DRVSEKHSQFVKKHTA--TEISVAHYTGRIIYDTRAFT 830
            ||..:..::|:.||..|..|:.|    :.:...:..|::..:.  |...:||:.|.:.|....|.
  Rat   502 KPMSIISLLDEESRFPQGTDVTMLQKLNSIHANNKSFLRPKSIHDTRFGIAHFAGDVYYQAEGFL 566

  Fly   831 DINRDFVPPEMIETFRSSLDESIMLMFTNQLTKAGNLTMPFEAVQHKDESERKSYALNTLSAGCI 895
            :.|||.:..:::....||.::.:..:|        ||.:|...:.|....:.|     |.:.|.|
  Rat   567 EKNRDVLSTDILILIHSSKNKFLKEIF--------NLDLPQTKLGHGTICQVK-----TKTGGQI 618

  Fly   896 SQVNNLR----TLAANFRFTCLTLLKMLSQNANLGVHFVRCIRADLEYKPRSFHSDVVQQQMKAL 956
            .:.::..    ||::.|:.:...|:|:|:   |...:|||||:.:...||..|..::..||::..
  Rat   619 FKPSDSTKRSVTLSSQFKQSLEQLMKILT---NCQPYFVRCIKPNEYKKPLLFDRELCIQQLRYS 680

  Fly   957 GVLDTVIARQKGFSSRLPFDEFLRRYQFLAFDFDEPVEMTKDN------CRLLFLRLKME-GWAL 1014
            |:::||..|:.||..|..||||.:|::.|   ...|..:...|      .|:..|.|..: .|.:
  Rat   681 GMMETVHIRKSGFPIRYTFDEFSQRFRVL---LPSPERVQFQNKHRQMTSRIADLCLGTDKEWKM 742

  Fly  1015 GKTKVFLRYYNDEFLARLYELQ-----------VKKVIKVQSMMRALLARKRV--------KG-- 1058
            ||||:||:.:.|..|    |:|           :::|::.....:..|.:||.        :|
  Rat   743 GKTKIFLKDHQDTML----EIQRSQALDGAAIRIQRVLRGHKYRKEFLRQKRAAVTLQAVWRGHN 803

  Fly  1059 -GKVFKLGKKGPEHHDVAASK--IQKAFRGFRDRV-----RLPPLVNEKSGQLNENTADFIRPFA 1115
             .|.|||...|.|.....|..  :.:.|:..|.::     |....:..:..|........|:..|
  Rat   804 QRKNFKLILMGFERLQAIARSHLLMRQFQTMRQKIVQLQARCRGYLVRQQVQAKRRAVVIIQAHA 868

  Fly  1116 K-------KWREKSIFQVLLHYRAARFQDFVNLSQQVHIYNQRMVAGLNKCTRAVPFERI--NMR 1171
            :       .|::||....::..:..:.|......::..||        :..|.....|::  .:.
  Rat   869 RGMVARKSYWQQKSSGPPVILAKEPKGQGVALDRKRKSIY--------DTVTDTAMVEKVFGFLP 925

  Fly  1172 EVNSSQLGPLPVPIKKMPFR--------LDQIPFYDTQYMVDPANSISRQAFPNQLLT------Q 1222
            .:...|.||.|...:.:..:        ||.:|.  |:...:..:.::...||...:|      .
  Rat   926 AMIGGQEGPAPTRFEDLEVKTQKLHEVDLDTVPM--TEMPGEDVDGLAEYTFPKFAVTYFQKSAS 988

  Fly  1223 HMEDDEPWDSPL--QRNPSMTSCALTY--------------NAYKKEQACQTN-----WDRMGES 1266
            |....:|...||  ..|.:..|.||..              .||.:.....::     .||: :.
  Rat   989 HTHIQKPLRYPLLYHENDTDHSAALAVWIIILRFMGDLPEPQAYGRSSLTGSSVMRQIHDRL-DK 1052

  Fly  1267 DNIYNQGYFRDPQQLRRNQMQMNMN 1291
            |:: .||    ||..|..|:....|
  Rat  1053 DSV-TQG----PQHNRSTQVASQQN 1072

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ninaC	NP_523503.2	STKc_myosinIII_N_like	9..282	CDD:270785
		MYSc_Myo21	346..1022	CDD:276848	183/701 (26%)
Myo7b	NP_001424233.1	None