Protein Alignment ninaC and myo6

DIOPT Version :10

• Sequence 1: NP_523503.2
• Gene: ninaC / 34012
• FlyBaseID: FBgn0002938
• Length: 1501
• Species: Drosophila melanogaster
• Sequence 2: XP_031758531.1
• Gene: myo6 / 493193
• XenbaseID: XB-GENE-1012303
• Length: 1300
• Species: Xenopus tropicalis
• Alignment Length: 1360
• Identity: 294/1360 - (21%)
• Similarity: 494/1360 - (36%)
• Gaps: 376/1360 - (27%)

  Fly   220 DGKPPFADMHPTRAMFQIIR----NPPPTLMRPTNWSQQINDFISESLEKNAENRPMMVEMVEHP 280
            ||||.:|. |||.. ||:.:    .|....:.|.|  |:...|::.
 Frog     3 DGKPVWAP-HPTDG-FQLGKIVDIGPDSLTIEPLN--QKGKTFLAP------------------- 44

  Fly   281 FLTELIENEDEMRSDIAEMLELSRDVKTLYKEPELFVDRGYVKRFDEKPEKMYPEDLAALENPVD 345
             :.::...|::....:.:...|                             ||..:...|.|
 Frog    45 -INQVFPAEEDTSKHVEDNCSL-----------------------------MYLNEATLLHN--- 76

  Fly   346 ENIIESLRHRILMGESYSFIGDILLSLN----------SNEIKQEFPQEFHAKYRFKSRSENQPH 400
                  ::.|....:.|:::.:||:::|          |.:|||         |..||.....||
 Frog    77 ------IQVRYSKDKIYTYVANILIAVNPYFDVPKLYTSEQIKQ---------YHGKSLGTLPPH 126

  Fly   401 IFSVADIAYQDMLHHKEPQHIVLSGESYSGKSTNARLLIKHLCYLGDGNRGATGRVESSIKAILM 465
            ::::||.|::||...|..|.|::||||.:||:.|.:.::::|.......:....|:..:...:..
 Frog   127 VYAIADKAFRDMKVLKMSQSIIVSGESGAGKTENTKFVLRYLTESYGSGQDIDERIVEANPLLEA 191

  Fly   466 LVNAGTPVNNDSTRCVLQYCLTFGKTGKMSGAVFNMYMLEKLRVATTDGTQHNFHIFYYFYDFIN 530
            ..||.|..||:|:|......:.|.:...:.|...:.|:|||.|:......:.|:||||.......
 Frog   192 FGNAKTVRNNNSSRFGKFVEIHFNEKNSVVGGFVSHYLLEKSRICVQGQDERNYHIFYRLCAGAP 256

  Fly   531 QQNQLKEYNLKADRNYRYLR-------VPPEVPPSKLKYRRDDPEGNVERYREFENILRDI--DF 586
            :..:.|.:....| .:|||.       ...:.....|:.|:...|....::...::.|.|.  ||
 Frog   257 EDIRQKLFLCSPD-TFRYLNRGCTRYFASKDTDKQILQNRKSPEEDEYLKHGALKDPLLDDHGDF 320

  Fly   587 NH-------------KQLETVRKVLAAILNIGNIRFRQNGKYA-----EVENTDIVSRIAELLRV 633
            |.             ::|:..| |:|.:|::|||.|.:.|..:     ..::::.:...|:||.:
 Frog   321 NRMCIAMKKIGLDDTEKLDLFR-VVAGVLHLGNIDFEEAGSTSGGCTLRKKSSESLQCCAKLLGL 384

  Fly   634 DEKKFMWSLTNFIMV------KGGIAERRQYTTEEARDARDAVASTLYSRLVDFIINRINMNMSF 692
            |:.....|||:.:|:      ||.:. :.....::|.:||||:|..:||.|.|.::||:|....|
 Frog   385 DQDDLQVSLTSRVMLTTAGGTKGTVI-KVPLKVQQAENARDALAKAIYSHLFDHVVNRVNQCFPF 448

  Fly   693 PRAVFGDTNAIIIHDMFGFECFNRNGLEQLMINTLNEQMQYHYNQRIFISEMLEMEAEDIDTINL 757
            .|:.|    .|.:.|:.|||.|..|..||..||..||::|..:|:||...|....:.|.:....:
 Frog   449 ERSSF----FIGVLDIAGFEYFEHNSFEQFCINYCNEKLQQFFNERILKEEQELYQKEGLGVNEV 509

  Fly   758 NFYDNKTALDNLLTKPDGLFYIIDDASRSCQDQDL-IMDRVSEKHSQFVKKHTATEIS------- 814
            ::.||:..:|.:..|..|:..|:|:.:|..|..|. ....|.:||    |.|....|.
 Frog   510 HYVDNQDCIDLIEAKLVGILDILDEENRLPQPTDQHFTSAVHQKH----KNHFRLTIPRKSKLAV 570

  Fly   815 -----------VAHYTGRIIYDTRAFTDINRDFVPPEMIETFRSSLDESIMLMFTNQLTKAGNLT 868
                       |.|:.|.:.|:|..|.:.|.|.:...:......|.|:     |..:|.::.|
 Frog   571 HRNIRDDEGFIVRHFAGAVCYETTQFVEKNNDALHMSLESLICESKDK-----FVRELFESAN-- 628

  Fly   869 MPFEAVQHKDESERKSYALNTLSAGCISQVNNLRTLAANFRFTCLTLLKMLSQNANLGVHFVRCI 933
                  .||| .::|:..|:.:|.|     |..:|.        |.||  |.:..:.|..|:|||
 Frog   629 ------NHKD-LKQKTGKLSFISVG-----NKFKTQ--------LNLL--LEKLRSTGSSFIRCI 671

  Fly   934 RADLEYKPRSFHSDVVQQQMKALGVLDTVIARQKGFSSRLPFDEFLRRYQFLAFDFDEPVEMTKD 998
            :.:|:.....|....:..|::..|::..:...|.||.||..|.|....|:...     |.:|::.
 Frog   672 KPNLKMTSHQFEGAQILSQLQCSGMVSVLDLMQGGFPSRASFHELYNMYKKYM-----PAKMSRL 731

  Fly   999 N----CRLLF--LRLKMEGWALGKTKVFLR-----------YYNDEFLARLYE--------LQVK 1038
            :    |:.||  |.|....:..|.||||.|           ..:.:.||.|..        .:.|
 Frog   732 DPRLFCKALFKALGLNENDYKFGLTKVFFRPGKFAEFDQIMKSDPDHLAELIRRVNHWLICSRWK 796

  Fly  1039 KV---------------------IKVQSMMRALLARK----RVKG--------------GKVFKL 1064
            ||                     ||:|..:|..|.||    |:.|              .:|...
 Frog   797 KVQWCALCVIKLKNKIQYRASACIKMQKTIRMWLCRKKHKPRIDGMVKVQTLKKRLDKFNEVVNA 861

  Fly  1065 GKKGPEHHDVAASKIQKAFRGFRDRVRLPPLVNEK-----------SGQL---------NENTAD 1109
            .|:|..........::.:......:::...:..|:           ||||         .|..|:
 Frog   862 LKEGKAEMSKQVKDLELSIDALLSKIKNTIMTREQIEREYDNLVKSSGQLLNSLQKRKKEEEEAE 926

  Fly  1110 FIRPF------------------------------------------AKKWREKSIFQVLLHYRA 1132
            .:...                                          .|:..|:...|..:..:.
 Frog   927 RLHKIQEEMERERKRREAEEELRRKEENERRLKAEIEAKRKQEEEERKKREEEEKRIQAEVEMQL 991

  Fly  1133 ARFQDFVNLSQQVHIYNQ----RMVAGLNKCTRAVPFERIN-------MREVNSSQLGPLPVPIK 1186
            ||  |....|||..|..|    |.:|.....:.|   |.||       :|......|.|.||..|
 Frog   992 AR--DREEESQQQAILEQERRDRELAMRIAQSEA---ELINEDGPDSALRSDTVGVLQPSPVNYK 1051

  Fly  1187 ----KMPFRLDQIPFYDTQYMVDPANSISRQAFPNQLLTQHMEDDEPWDSPLQRNPSMTSCAL-- 1245
                :....::::    .:.|.|..:...:........:....|...|.....|:...|||.:
 Frog  1052 AGEDRTKLTMEEM----AKEMTDILSRGGQVQATKSAASVKKHDLSKWKYAELRDAINTSCDIEL 1112

  Fly  1246 -------------TYNAYK---KEQACQTNWDRMGESDNIYNQGYF--RDPQ-----QLRRNQMQ 1287
                         .|:|:|   |::...|. .|..:|...|:...|  ..||     ||...|.:
 Frog  1113 LAACREEFHRRLKVYHAWKSKNKKRNADTE-QRAPKSVTDYDFAPFMNNSPQQNPVVQLPARQQE 1176

  Fly  1288 MNMNAYNNAY--------NSYNSNYNNQN--WGVHRSG---SRRNSLKGYAAPPPPPPPM 1334
            :.||.....:        :.|....|.:.  |..|..|   :|:..|.     |..||.|
 Frog  1177 IEMNRQQRYFRIPFIRPADQYKDPQNKKKGWWYAHFDGPWIARQMELH-----PDKPPIM 1231

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ninaC	NP_523503.2	STKc_myosinIII_N_like	9..282	CDD:270785	15/65 (23%)
		MYSc_Myo21	346..1022	CDD:276848	189/743 (25%)
myo6	XP_031758531.1	Myosin_N	2..40	CDD:460670	14/40 (35%)
		MYSc_Myo6	71..761	CDD:276833	191/752 (25%)
		CBD_MYO6-like	772..916	CDD:409646	23/143 (16%)
		MYO6_MIU_linker	1001..1074	CDD:412090	17/79 (22%)
		MyUb_Myo6	1088..1128	CDD:439319	6/39 (15%)
		Myosin-VI_CBD	1183..1273	CDD:465157	11/54 (20%)