Protein Alignment ninaC and jar

DIOPT Version :10

• Sequence 1: NP_523503.2
• Gene: ninaC / 34012
• FlyBaseID: FBgn0002938
• Length: 1501
• Species: Drosophila melanogaster
• Sequence 2: NP_001014650.2
• Gene: jar / 42889
• FlyBaseID: FBgn0011225
• Length: 1268
• Species: Drosophila melanogaster
• Alignment Length: 1363
• Identity: 301/1363 - (22%)
• Similarity: 546/1363 - (40%)
• Gaps: 324/1363 - (23%)

  Fly   320 GYV---------KRFDEKP-EKMYP------EDL-AALENPVDEN------------IIESLRHR 355
            ||:         |.|:..| ::.||      :|: ::.:.|.|.:            .:::|:.|
  Fly    16 GYIQGRITEIGAKEFEVTPTDRKYPKRTCHFDDIHSSCDGPQDHDDNCELMLLNEATFLDNLKTR 80

  Fly   356 ILMGESYSFIGDILLSLNS-NEIKQEFPQEFHAKYRFKSRSENQPHIFSVADIAYQDMLHHKEPQ 419
            ....:.|:::.:||:::|. .|||:.:..:...||..:|..|..||:|::||.|.:||..:|..|
  Fly    81 YYKDKIYTYVANILIAVNPYREIKELYAPDTIKKYNGRSLGELPPHVFAIADKAIRDMRVYKLSQ 145

  Fly   420 HIVLSGESYSGKSTNARLLIKHLCYLGDGNRGATGRVESSI----KAILMLVNAGTPVNNDSTRC 480
            .|::||||.:||:.:.:.|:|:|||..|    :.|.:|:.|    ..:....||.|..||:|:|
  Fly   146 SIIVSGESGAGKTESTKYLLKYLCYSHD----SAGPIETKILDANPVLEAFGNAKTTRNNNSSR- 205

  Fly   481 VLQYCLTFGK--------TGKMSGAVFNMYMLEKLRVATTDGTQHNFHIFYYFYDFINQQNQLKE 537
                   |||        ..::.|...:.|:|||.|:.|....:.|:|:||.......||.:.|
  Fly   206 -------FGKFIEVHYDAKCQVVGGYISHYLLEKSRICTQSAEERNYHVFYMLLAGAPQQLRDK- 262

  Fly   538 YNLKADRNYRYL---------RVPPEVPPSKLKYRRDDPEGN-----VERYREFENI---LRDID 585
            .:|....:||||         ....::.|...|.:....:|.     ::.|:.|.|:   |..:.
  Fly   263 LSLGKPDDYRYLSGCTQYFANAKTEQLIPGSQKSKNHQQKGPLKDPIIDDYQHFHNLDKALGRLG 327

  Fly   586 FNHKQLETVRKVLAAILNIGNIRFRQ------NGKYAEVENTDIVSRIAELLRVDEKKFMWSLTN 644
            .:..:...:..::||:|::|||.|.:      .|......:...::..:.||.||:.:...:|.:
  Fly   328 LSDTEKLGIYSLVAAVLHLGNIAFEEIPDDVRGGCQVSEASEQSLTITSGLLGVDQTELRTALVS 392

  Fly   645 FIM-VKGG-------IAERRQYTTEEARDARDAVASTLYSRLVDFIINRINMNMSFPRAVFGDTN 701
            .:| .|||       :...:.|   ||.:||||:|..:||||.|.|:..||.::.|..:.|
  Fly   393 RVMQSKGGGFKGTVIMVPLKIY---EASNARDALAKAIYSRLFDRIVGLINQSIPFQASNF---- 450

  Fly   702 AIIIHDMFGFECFNRNGLEQLMINTLNEQMQYHYNQRIFISEMLEMEAEDIDTINLNFYDNKTAL 766
            .|.:.|:.|||.|..|..||..||..||::|..:|..|..:|....:.|.::...:.|.||:..:
  Fly   451 YIGVLDIAGFEYFTVNSFEQFCINYCNEKLQKFFNDNILKNEQELYKREGLNVPEITFTDNQDII 515

  Fly   767 DNLLTKPDGLFYIIDDASRSCQDQDLIMDRVSEKH-------------------SQFVKKHTATE 812
            :.:..|.:|:|.::|:.|:        :.:.|..|                   |..:|.|....
  Fly   516 ELIEAKSNGIFTLLDEESK--------LPKPSYSHFTAEVHKSWANHYRLGLPRSSRLKAHRTLR 572

  Fly   813 ----ISVAHYTGRIIYDTRAFTDINRDFVPPEMIETFRSSLDESIMLMFTNQLTKAGNLTMPFEA 873
                ..|.|:.|.:.|:|..|.:.|.|.:... :|......|..::    ..|..:|:.|    :
  Fly   573 DEEGFLVRHFAGAVCYNTEQFIEKNNDALHAS-LEGLVQECDNPLL----QTLFPSGSST----S 628

  Fly   874 VQHKDESERKSYALNTLSAGCISQVNNLRTLAANFRFTCLTLLKMLSQNANLGVHFVRCIRADLE 938
            |:.|         ||.:|.|            :.|:.....|::.|.||   |.:|:|||:.:.:
  Fly   629 VRGK---------LNFISVG------------SKFKTQLGELMEKLEQN---GTNFIRCIKPNSK 669

  Fly   939 YKPRSFHSDVVQQQMKALGVLDTVIARQKGFSSRLPFDEFLRRYQFLAFDFDEPVEM----TKDN 999
            ...|.|...:...|:|..|.:..:...:.|:.||:.|.:....|:.:.     |.|:    .:..
  Fly   670 MIDRQFEGSLALAQLKCSGTISVLELMEHGYPSRVLFADLYSMYKSVL-----PPELVSLPARTF 729

  Fly  1000 CRLLF--LRLKMEGWALGKTKVF------------LRYYNDEFLARLYELQVKK----------- 1039
            |..:|  |.|..:.:..|.||||            :|...:..||.:  .:|||
  Fly   730 CEAMFQSLNLSAKDFKFGITKVFFRPGKFVEFDRIMRSDPENMLAIV--AKVKKWLIRSRWVKSA 792

  Fly  1040 -----VIKV--------------QSMMRALLARK----RVKG-GKVFKLGKKGPEHHDVAA---- 1076
                 |||:              |.:.|..||||    |.:| ||:.|:.....:..::|:
  Fly   793 LGALCVIKLRNRIIYRNKCVLIAQRIARGFLARKQHRPRYQGIGKINKIRTNTLKTIEIASGLKM 857

  Fly  1077 ------SKIQKAFRGFRD---RVRLPPLVNEKS---------GQLNENTADFIRPFAKKW----- 1118
                  |.:...:|...|   ::::.|.:.::.         ..:|:.|.|......::.
  Fly   858 GREEIISGVNDIYRQIDDAIKKIKMNPRITQREMDSMYTVVMANMNKLTVDLNTKLKEQQQAEEQ 922

  Fly  1119 -REKSIFQVLLHYRAARFQDFVNLSQQVHIYNQRMVAGLNKCTRAVPFERINMREVNSSQLGPLP 1182
             |.:.|.:.|...|||:  :.....|:..|.|:|:.|.:....:|...:|:...|.:......|.
  Fly   923 ERLRKIQEALEAERAAK--EAEEQRQREEIENKRLKAEMETRRKAAEAQRLRQEEEDRRAALALQ 985

  Fly  1183 VPIKK-----MPFR--LDQIPFYDTQYMVDPANSISRQAFPNQLLTQHMEDDEPW-------DSP 1233
            ..::|     ..:|  |:| ...|.:..:..||..:.|          :||..|.       .||
  Fly   986 EQLEKEAKDDAKYRQQLEQ-ERRDHELALRLANESNGQ----------VEDSPPVIRNGVNDASP 1039

  Fly  1234 LQRNPSMTSCALTYNAYKKEQACQTNWDRMGESDNIYNQGYFRDPQQLRRNQMQMNMNAYNNAYN 1298
            :..|..::...:..|...:         .:.:|:|:..|     .|.|.:.:..::...|:...:
  Fly  1040 MGPNKLISFSQVVSNIASR---------YLNKSENVRAQ-----QQALGKQKYDLSKWKYSELRD 1090

  Fly  1299 SYNSNYNNQNWGVHRSGSRRNSLKGYAAPPPPPPPMPSSNYYRNNPNQQQRNYQQRS------SY 1357
            :.|::.:.:.....|....|. ||.|.|       ..:.|..|...::.:|  ..||      ..
  Fly  1091 AINTSCDIELLEACRQEFHRR-LKVYHA-------WKAKNRKRTTMDENER--APRSVMEAAFKQ 1145

  Fly  1358 PP-SDPVRELQNMARNEGDNSEDPPFNFKAMLRKTNYPRGSETNTY--DFNNRRGSDSGDQHTFQ 1419
            || ..|::|:......          .|:....:.|.|..::...:  .|:.:..:...:.|..:
  Fly  1146 PPLVQPIQEIVTAQHR----------YFRIPFMRANAPDNTKRGLWYAHFDGQWIARQMELHADK 1200

  Fly  1420 PPKLRSTGRRYQDDEGYNSSSGNYGVSRKFGQQQRAPTLRQSPASVGRSFEDSNARSFEEAGS 1482
            ||.|...|.  .|.:....|....|::||.|    |..|..   ...|.:|.:..::::..|:
  Fly  1201 PPILLVAGT--DDMQMCELSLEETGLTRKRG----AEILEH---EFNREWERNGGKAYKNLGA 1254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ninaC	NP_523503.2	STKc_myosinIII_N_like	9..282	CDD:270785
		MYSc_Myo21	346..1022	CDD:276848	191/772 (25%)
jar	NP_001014650.2	Myosin_N	7..49	CDD:460670	7/32 (22%)
		MYSc_Myo6	71..754	CDD:276833	191/748 (26%)
		CBD_MYO6-like	765..913	CDD:409646	28/149 (19%)
		ERM_helical	<954..1020	CDD:466641	13/66 (20%)
		MYO6_MIU_linker	1002..1093	CDD:480843	19/115 (17%)
		MyUb_Myo6	1076..1116	CDD:439319	6/40 (15%)
		Myosin-VI_CBD	1160..1246	CDD:465157	19/104 (18%)