Protein Alignment ninaC and myo1eb

DIOPT Version :10

• Sequence 1: NP_523503.2
• Gene: ninaC / 34012
• FlyBaseID: FBgn0002938
• Length: 1501
• Species: Drosophila melanogaster
• Sequence 2: NP_956930.1
• Gene: myo1eb / 393609
• ZFINID: ZDB-GENE-040426-1347
• Length: 1096
• Species: Danio rerio
• Alignment Length: 1193
• Identity: 286/1193 - (23%)
• Similarity: 486/1193 - (40%)
• Gaps: 268/1193 - (22%)

  Fly   335 EDLAALENPVDENIIESLRHRILMGESYSFIGDILLSLNSNEIKQEFPQEFHAKYRFKSRSENQP 399
            :|:..|....::.|.::|:.|.:....:::||.:|:|:|..:....|.......|:..::.||.|
Zfish    20 DDMVLLSKITEDAITDNLKKRYMDDYIFTYIGPVLISVNPFKQLPYFTDREIELYQGAAQYENPP 84

  Fly   400 HIFSVADIAYQDMLHHKEPQHIVLSGESYSGKSTNARLLIKHLCYLGDGNRGATGRVESSIKAIL 464
            ||:::||..|::|:...|.|.:::||||.:||:..|:.::.::..:..|     |.....:|.|:
Zfish    85 HIYALADNMYRNMMIDSENQCVIISGESGAGKTVAAKYIMSYISKVSGG-----GPKVQHVKDII 144

  Fly   465 M--------LVNAGTPVNNDSTRCVLQYCLTFGKTGKMSGAVFNMYMLEKLRVATTDGTQHNFHI 521
            :        ..||.|..||:|:|....:.:.|.:.|:..|...:.::|||.||.:.:..:.||||
Zfish   145 LQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISNFLLEKSRVVSQNNGERNFHI 209

  Fly   522 FYYFYDFINQQNQLKEYNLKADRNYRYLRVPPEVPPSKLKYRRDDPEGNVERYREFE---NILRD 583
            :|.......:: |.:...:.....|.||.       ....|..:|    |...:|||   |.:..
Zfish   210 YYQLLKGATKE-QRENLGVTTPDYYFYLN-------QSDTYTVED----VNDKKEFEDTMNAMSV 262

  Fly   584 IDFNHKQLETVRKVLAAILNIGNIRFRQNGKYAEVENTDIVSRIAELLRVDEKKFMWSLTNFIMV 648
            :..:....::|.:::|.||::|||.||:.|.||.||:.|.::..:.||.:::......||:.||.
Zfish   263 VGLSMDAQDSVLQIVAGILHLGNIAFREEGNYAVVESEDFLAFPSYLLGINQDGLKSKLTSRIMD 327

  Fly   649 K--GGIAERRQYT--TEEARDARDAVASTLYSRLVDFIINRINMNMSFPRAVFGDTNAIIIHDMF 709
            .  ||..|....|  ||:|...|||::..|||||.|::::.||..|...|....    |.:.|::
Zfish   328 SKWGGKTETISVTLNTEQASFTRDALSKALYSRLFDYLVDAINKAMQKDREELN----IGVLDIY 388

  Fly   710 GFECFNRNGLEQLMINTLNEQMQYHYNQRIFISEMLEMEAED-----IDTINLNFYDNKTALDNL 769
            |||.|.:||.||..||.:||::     |:|||...|:.|.|:     |....:.:::||...|.:
Zfish   389 GFEIFQKNGFEQFCINFVNEKL-----QQIFIELTLKAEQEEYVQEGISWTPIEYFNNKVVCDLI 448

  Fly   770 LTK--PDGLFYIIDD------ASRSCQDQDLIMDRVSE--KHSQFVKKHTATEISVAHYTGRIIY 824
            .:|  |.|:..|:||      |.....||.|:....|:  .|..|...:..  ..|.||.|::.|
Zfish   449 ESKLNPPGIMSILDDVCATMHAKGEGADQTLLQKLQSQIGTHEHFNSWNKG--FVVHHYAGKVSY 511

  Fly   825 DTRAFTDINRDFVPPEMIETFRSSLDESIMLMFTNQLTKAGNLTMPFEAVQHKDESERKSYALNT 889
            |...|.:.|||.:..::||..:||....|..:|...:                 |:|::... .|
Zfish   512 DVSGFCERNRDVLFSDIIELMQSSEFAFIKGLFPENI-----------------EAEKRGRP-TT 558

  Fly   890 LSAGCISQVNNLRTLAANFRFTCLTLLKMLSQNANLGVHFVRCIRADLEYKPRSFHSDVVQQQMK 954
            ..:....|.|.|          ..||:|...       |::|||:.:...|.|.:....|:.|::
Zfish   559 AGSKIKKQANTL----------VQTLMKCTP-------HYIRCIKPNETKKSRDWEESRVKHQVE 606

  Fly   955 ALGVLDTVIARQKGFSSRLPFDEFLRRYQFLAFDF------DEPVEMTKDNCRLLFLRLKMEG-- 1011
            .||:.:.:..|:.|::.|..|.:||.||..|..:.      ||     |.....|...:.|:.
Zfish   607 YLGLRENIRVRRAGYAFRRIFKKFLHRYAILTRETWPQWRGDE-----KQGVLHLLKSVNMDSDQ 666

  Fly  1012 WALGKTKVFLRYYNDEFLARLYELQVKK------VIKVQSMMRALLARKRVKGGKVFKLGKKGPE 1070
            :.|||||:|::.....||  |.|::.:|      ||: |:..:.:..||.|         :...|
Zfish   667 YQLGKTKIFIKAPESLFL--LEEMRERKYNGYARVIQ-QAWRKHIAVRKYV---------RMREE 719

  Fly  1071 HHDVAASKIQKAFRGFRDRVRLPPLVNEKSGQLNEN-TADF--------IRPFAKKWREKSIF-Q 1125
            ..|:..:|.::                 :...||.| ..|:        ||.|..: ||:..| .
Zfish   720 ASDLLLNKKER-----------------RKNSLNRNFVGDYIGTDNHPEIRQFVGR-RERIDFAD 766

  Fly  1126 VLLHYRAARF----QDFVNLSQQVHIYNQRMV-AGLNK-CTRAVPFERINMREVNSSQLGPLPVP 1184
            |::.| ..||    :|.:...:.:::..:..| .|..| ..|.|...:|.:.::.|..|..|
Zfish   767 VVVKY-DRRFKSVKRDLILTPKFLYLIGREKVKQGPEKGQIREVLKRKIEVEKIQSVSLSTL--- 827

  Fly  1185 IKKMPFRLDQIPFYDTQYMVDPANSISRQAFPNQ---LLTQHMEDDEPWDSPLQRN--------- 1237
                  :.|....::.||     :|:.:..|..:   ||.:..|:......||:.|
Zfish   828 ------QDDIFILHEDQY-----DSVLQSVFKTEFLSLLYKRFEEKTKKKLPLKFNNLLEFKVKK 881

  Fly  1238 ---------------------------PSMTSCALTYNAYKKEQACQTNWDR-----MGESDNIY 1270
                                       ||.....::..:...:....|..|.     ||..:...
Zfish   882 GGWGPFASAGSRQIQFQMGQGDDAVLKPSSKILTVSIGSGLPKNTRPTRRDNRKSSFMGNQNRSA 946

  Fly  1271 NQGYFRDP--------------QQLRRNQMQMNMNAYNNAYNSYNSNYNNQNW------------ 1309
            .| |.|:.              ..|.|.|..|:.........|..|...:|.:
Zfish   947 GQ-YSREAPKSAGRGRGQPAVRHSLLRQQSTMDQPTLPRLQGSVRSQRESQVYTDMGFMKVPDQG 1010

  Fly  1310 --GVHRSGSRR-NSLKGYAAPPPPPPPMP-----SSNYYRNNPNQQQRNYQQRSSYPPSDPVREL 1366
              |:||..|:. ..|.|...|.|.|.|:|     .:.|..:..:..:.::|      |.|.:..|
Zfish  1011 VAGMHRRRSKEYKPLPGSGRPKPSPKPVPRTPRCKALYAYDAQDTDELSFQ------PDDIIEIL 1069

  Fly  1367 QNMARNEGDNSEDPPFNFKAMLR 1389
                      ||||...::..||
Zfish  1070 ----------SEDPSGWWQGRLR 1082

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ninaC	NP_523503.2	STKc_myosinIII_N_like	9..282	CDD:270785
		MYSc_Myo21	346..1022	CDD:276848	197/713 (28%)
myo1eb	NP_956930.1	MYSc_Myo1	31..677	CDD:276829	197/713 (28%)
		Myosin_TH1	717..918	CDD:461801	40/233 (17%)
		SH3_MyoIe_If_like	1043..1095	CDD:212761	11/56 (20%)