Protein Alignment ninaC and Myo3b

DIOPT Version :9

• Sequence 1: NP_523503.2
• Gene: ninaC / 34012
• FlyBaseID: FBgn0002938
• Length: 1501
• Species: Drosophila melanogaster
• Sequence 2: NP_001380706.1
• Gene: Myo3b / 366069
• RGDID: 1560313
• Length: 1333
• Species: Rattus norvegicus
• Alignment Length: 1160
• Identity: 392/1160 - (33%)
• Similarity: 618/1160 - (53%)
• Gaps: 106/1160 - (9%)

  Fly     2 MYLPYAQLPDPTDKFEIYEEIAQGVNAKVFRAKELDNDRIVALKI----QHYDEEHQVSIEEEYR 62
            |.|....||||.|.:||.|.|.:|...||::.....:..:.|:||    ...|||    :|.||.
  Rat    29 MMLRLESLPDPMDTWEIRETIGKGTYGKVYKVANRRDGSLAAVKILDSVNDVDEE----VEAEYN 89

  Fly    63 TLRDYCDHPNLPEFYGV-YKLSKPNGPDEIWFVMEYCAGGTAVDMVNKLLKLDRRMREEHIAYII 126
            .|:....|||:.:|||: ||..:..| .::|.|:|.|.||:..::|..||:..:|:.|..|:||:
  Rat    90 ILQFLPSHPNVVKFYGMFYKADRCVG-GQLWLVLELCNGGSVTELVKGLLRCGKRLDEALISYIL 153

  Fly   127 RETCRAAIELNRNHVLHRDIRGDNILLTKNGRVKLCDFGLSRQVDSTLGKRGTCIGSPCWMAPEV 191
            ..:......|:.:.::|||::|:|||||..|.|||.|||:|.|:.||..:|.|.:|:|.||||||
  Rat   154 YGSLLGLQHLHHHRIIHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRLRRNTSVGTPFWMAPEV 218

  Fly   192 VSAMESREPDITVRADVWALGITTIELADGKPPFADMHPTRAMFQIIRNPPPTLMRPTNWSQQIN 256
            ::..:..:.....|.|||:||||.|||.||.||..:|||.:.:|:|.|||||||:.|.||.::.|
  Rat   219 IACEQQYDSSYDARCDVWSLGITAIELGDGDPPLFEMHPVKMLFKIPRNPPPTLLHPDNWCEEFN 283

  Fly   257 DFISESLEKNAENRPMMVEMVEHPFLTELIENEDEMRSDIAEMLELSRDVKTLYKEPELFVDRGY 321
            .|||:.|.|:.|.||.:..:::|||:.........::..:|::|...:....:.|.....:..|.
  Rat   284 HFISQCLIKDFEKRPSVTHLLDHPFIKGTQGKVLFLQKQLAKVLWDQKHQNPVAKTRHERMHTGR 348

  Fly   322 VKRFDEKPEKMYPEDLAALENPVDENIIESLRHRILMGESYSFIGDILLSLNSNEIKQEFPQEFH 386
            ....::..:....:||..||...::.||..|:.|......|:::||||::||..:....:..:|.
  Rat   349 PHHVEDAGKCCLEDDLVNLEVLDEDTIIYWLQKRYADALIYTYVGDILIALNPFQNLSIYSPQFS 413

  Fly   387 AKYRFKSRSENQPHIFSVADIAYQDMLHHKEPQHIVLSGESYSGKSTNARLLIKHLCYLGDGN-- 449
            ..|....||.|.||||:.||.|||.::...:.|.||:||||.|||:.||.|:::||.:||..|
  Rat   414 RLYHGVKRSSNPPHIFASADNAYQCLVTFSKDQCIVISGESGSGKTENAHLIVQHLTFLGKANNQ 478

  Fly   450 --RGATGRVESSIKAILMLVNAGTPVNNDSTRCVLQYCLTFGKTGKMSGAVFNMYMLEKLRVATT 512
              |....:|.|.::|   ..||.|.:|::|:|......:.|..||.:.||..:.|:|||.||...
  Rat   479 TLRQKILQVNSLVEA---FGNARTAINDNSSRFGKYLEMMFTPTGAVMGARISEYLLEKSRVIQQ 540

  Fly   513 DGTQHNFHIFYYFYDFINQQNQLKEYNLKADRNYRYL-----RVPPEVPPSKLKYRRDDPEGNVE 572
            ...:.|||||||.|..:..|.:|.|:.|..::..||:     ||..:: .||..|||
  Rat   541 AAGEKNFHIFYYIYAGLYHQKKLAEFRLPEEKPPRYIAAETERVTQDI-TSKESYRR-------- 596

  Fly   573 RYREFENILRDIDFNHKQLETVRKVLAAILNIGNIRF------RQNGKYAEVENTDIVSRIAELL 631
            ::...::..|.|.|..|::.:|.::||.|||||||.|      .|..| :||.|.:.:...|.:|
  Rat   597 QFDVIQHCFRIIGFTDKEVHSVYRILAGILNIGNIEFAAISSQHQTDK-SEVPNPEALENAASVL 660

  Fly   632 RVDEKKFMWSLTNFIMVKGGIAERRQYTTEEARDARDAVASTLYSRLVDFIINRINMNMSFPRAV 696
            .::.::...:||:..:|..|....|..|.:.|.|.|||::..||.||..:|:||||..:...:.:
  Rat   661 CINSEELQEALTSHCVVTRGETIVRANTVDRAEDVRDAMSKALYGRLFSWIVNRINTLLQPDKNI 725

  Fly   697 FG--DTNAIIIHDMFGFECFNRNGLEQLMINTLNEQMQYHYNQRIFISEMLEMEAEDIDTINLNF 759
            ..  |...:.|.|:||||.|.||..|||.||..|||:|:::||.:|..|.:|.:.|.:|.:.:.:
  Rat   726 CSAEDRMNVGILDIFGFEDFQRNSFEQLCINIANEQVQFYFNQHVFALEQMEYKKEGVDAVLVQY 790

  Fly   760 YDNKTALDNLLTKPDGLFYIIDDASRSCQ--DQDLIMDRVSEKHSQFVKKHTATEIS--VAHYTG 820
            .||:..||..|.||.||..::|:.||..|  ||.|:.........:|..:....|:|  :.||.|
  Rat   791 EDNRPLLDMFLQKPLGLLALLDEESRFPQGTDQTLVDKFEDNLRCKFFWRPKGVELSFGIQHYAG 855

  Fly   821 RIIYDTRAFTDINRDFVPPEMIETFRSSLDESIMLMFTNQLTKAGNL------------TMP--- 870
            .::||.....:.|||.:|.:::...|:|.::.:..:|:..|||.|||            ::|
  Rat   856 PVLYDASGVLEKNRDTLPADVVVVLRTSENKLLQQLFSIPLTKTGNLAQTRARITASSRSLPPHF 920

  Fly   871 ---------FEAVQHKDESERKSYALNTLSAGCISQVNNLR--TLAANFRFTCLTLL-KMLSQNA 923
                     .|.::|.:|:                  .|::  |:|:.||::.:.|| ||:....
  Rat   921 SAGRAKVDTLEVIRHPEET------------------TNMKRQTMASYFRYSLMDLLSKMVVGQP 967

  Fly   924 NLGVHFVRCIRADLEYKPRSFHSDVVQQQMKALGVLDTVIARQKGFSSRLPFDEFLRRYQFLAFD 988
                ||||||:.:.:.|...|..|.|..|:::.|:|:||..|::|:|.|:.|:||:|||.:|||.
  Rat   968 ----HFVRCIKPNDDRKALQFSQDRVLAQLRSTGILETVSIRRQGYSHRILFEEFVRRYYYLAFR 1028

  Fly   989 FDEPVEMTKDNCRLLFLRLKMEGWALGKTKVFLRYYNDEFLARLYELQVKKVIKVQSMMRALLAR 1053
            ..:.....|::|..:..:.:::.|.||||||||:||:.|.|..|....:.:|:.:|:..:..|..
  Rat  1029 AHQTPPANKESCVAILEKSRLDHWVLGKTKVFLKYYHIEQLNLLLREVMGRVVMLQAYTKGWLGA 1093

  Fly  1054 KRVKGGKVFKLGKKGPEHHDVAASKIQKAFRGFRDRVRLPPLVNEKSGQLNENTA 1108
            :|.|..|         |..:.:|..||.|:||:..|.:.    .:...:.||:.|
  Rat  1094 RRYKRAK---------EKREKSAITIQSAWRGYDTRRKF----KQTRHRRNESAA 1135

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ninaC	NP_523503.2	STKc_myosinIII_N_like	9..282	CDD:270785	117/277 (42%)
		S_TKc	16..282	CDD:214567	112/270 (41%)
		MYSc	327..1034	CDD:214580	251/754 (33%)
		MYSc_Myo21	346..1022	CDD:276848	241/723 (33%)
Myo3b	NP_001380706.1	MYSc_Myo3	373..1062	CDD:276830	241/723 (33%)
		IQ	1102..1124	CDD:197470	7/25 (28%)
		PKc_like	20..310	CDD:419665	120/285 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	626	1.000	Inparanoid score	I822
OMA	1	1.010	-	-		QHG52654
OrthoDB	1	1.010	-	-		D25137at33208
OrthoFinder	1	1.000	-	-		FOG0003766
OrthoInspector	1	1.000	-	-		otm44567
orthoMCL	1	0.900	-	-		OOG6_104503
Panther	1	1.100	-	-	O	PTHR46256
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2623
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.980