Protein Alignment ninaC and didum

DIOPT Version :10

• Sequence 1: NP_523503.2
• Gene: ninaC / 34012
• FlyBaseID: FBgn0002938
• Length: 1501
• Species: Drosophila melanogaster
• Sequence 2: NP_724569.1
• Gene: didum / 35680
• FlyBaseID: FBgn0261397
• Length: 1800
• Species: Drosophila melanogaster
• Alignment Length: 1313
• Identity: 305/1313 - (23%)
• Similarity: 529/1313 - (40%)
• Gaps: 285/1313 - (21%)

  Fly   297 AEMLELSRDVKTLYKEPELFV----DRGYVKRFDEKPEKMYPEDLAALENP---VDEN------- 347
            |:::..|..::..|::...|:    |.|.:|....|.:   ..||..|.||   |.:|
  Fly    19 ADLVWESATLEESYRKGAGFLKICTDSGKLKEVKLKAD---GSDLPPLRNPAILVGQNDLTTLSY 80

  Fly   348 -----IIESLRHRILMGE-SYSFIGDILLSLNSNEIKQEFPQEFHAKYRFKSRSENQPHIFSVAD 406
                 ::.:||.|....: .|::.|.||:::|.......:.......||..:..:.:||||::|:
  Fly    81 LHEPGVLHNLRVRFCERQIIYTYCGIILVAINPYAEMPLYGPSIIRAYRGHAMGDLEPHIFALAE 145

  Fly   407 IAYQDMLHHKEPQHIVLSGESYSGKSTNARLLIKHLCYLGDGNRGATGRVESSIKAILMLV---- 467
            .||..:........|::||||.:||:.:|:..:::...:| |:...| :||..:.|...::
  Fly   146 EAYTKLERENCNLSIIVSGESGAGKTVSAKYAMRYFAAVG-GSESET-QVERKVLASSPIMEAFG 208

  Fly   468 NAGTPVNNDSTRCVLQYCLTFGKTGK-----------MSGAVFNMYMLEKLRVATTDGTQHNFHI 521
            ||.|..|::|:|        |||..|           :.||..:.|:|||.||......:.|:||
  Fly   209 NAKTTRNDNSSR--------FGKFTKLLFRNQMGVMFLQGATMHTYLLEKSRVVYQAQGERNYHI 265

  Fly   522 FYYFYDFINQQNQLKEYNLKADRNYRYLRV--PPEVPPSKLKYRRDDPEGNVERYREFENILRDI 584
               ||.....:::..|..|.....:::|.:  .||:          :...:.|::.|....:..:
  Fly   266 ---FYQLCAARSKYPELVLDHQDKFQFLNMGGAPEI----------ERVSDAEQFNETVQAMTVL 317

  Fly   585 DFNHKQLETVRKVLAAILNIGNI----RFRQNGKYAEVENTDI------VSRIAELLRV---DEK 636
            .|:.:|:..:.|:||.||::|||    :|.:..:..:.::.||      :...|:||||   |.:
  Fly   318 GFSIQQIADIVKILAGILHLGNIQVSKKFNEGSEEEDSDSCDIFHNDIHLQITADLLRVSADDLR 382

  Fly   637 KFMW-----SLTNFIMVKGGIAERRQYTTEEARDARDAVASTLYSRLVDFIINRIN--MNMSFPR 694
            :::.     |:..::::...|        |.|:.||||:|..:|::|..:|:..:|  :|....:
  Fly   383 RWLLMRKIESVNEYVLIPNSI--------EAAQAARDALAKHIYAKLFQYIVGVLNKSLNNGSKQ 439

  Fly   695 AVFGDTNAIIIHDMFGFECFNRNGLEQLMINTLNEQMQYHYNQRIFISEMLEMEAEDIDTINLNF 759
            ..|     |.:.|::|||.|..|..||..||..||::|..:||.:|..|..|...|.|....::|
  Fly   440 CSF-----IGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNQHVFKLEQEEYLKEGITWTMIDF 499

  Fly   760 YDNKTALDNLLTKPDGLFYIIDDASRSCQDQD------LIMDRVSEKHSQFVK-KHTATEISVAH 817
            |||:..:| |:....|:..::|:..|..:..|      ||  ....|...|.| :...|...:.|
  Fly   500 YDNQPCID-LIESRLGVLDLLDEECRMPKGSDESWAGKLI--GKCNKFPHFEKPRFGTTSFFIKH 561

  Fly   818 YTGRIIYDTRAFTDINRDFVPPEMIETFRSSLDESIMLMFTNQLTKAGNLTMPFEAVQHKDESER 882
            ::..:.||...|.:.|||.|..|:.:.    |.||.|     .|.|.   .|..|.:........
  Fly   562 FSDTVEYDVNGFLEKNRDTVSKELTQV----LSESNM-----SLAKQ---VMTLEEIDTLCVDSA 614

  Fly   883 KSYALN---TLSAGCISQVNNLR-----------TLAANFRFTCLTLLKMLSQNANLGVHFVRCI 933
            ||..|.   .:|||...|.|:.|           |:.:.|:.:..:|:..|....   .|:||||
  Fly   615 KSSTLGGRVVISAGRKQQGNDTRRRVVPSKQHRKTVGSQFQESLASLISTLHATT---PHYVRCI 676

  Fly   934 RADLEYKPRSFHSDVVQQQMKALGVLDTVIARQKGFSSRLPFDEFLRRYQFLAFDFDEPVEMTKD 998
            :.:.:.....:.:..:.||::|.|||:||.....||.||..:.:|..|||.|.:.........|.
  Fly   677 KPNDDKVAFKWETAKIIQQLRACGVLETVRISAAGFPSRWLYPDFYMRYQLLVYRSKLDKNDMKL 741

  Fly   999 NCRLLFLR--LKMEGWALGKTKVFLRYYNDEFLARL-YELQVKKVIKVQSMMRALLARKRVKGGK 1060
            :||.:.::  ...:.:..|.|::|.|.....||.:: ..|:.|.:..|||::|..:.|:     :
  Fly   742 SCRNIVMKWIQDEDKYRFGNTQIFFRAGQVAFLEQVRANLRKKYITIVQSVVRRFVYRR-----Q 801

  Fly  1061 VFKLGKKGPEHHDVAASKIQKAFRGFRDRVRLPPLVNEKSGQLNENTA----------------D 1109
            ..::.|        ..:.|||..||:..|.|...:...::|.:....|                .
  Fly   802 FLRIQK--------VINGIQKHARGYLARERTQKMREARAGLILSKYARGWLCRRRYLRLRHSIS 858

  Fly  1110 FIRPFAKKWREKSIFQVLL-HYRAARFQDFVNLSQQVHIYNQRMVAGLNKCTRAVPFERINMREV 1173
            .|:.:|:....::.|..:. ||||.:.|.||..:.....|.:|. ..:..|..|:  .|...|.
  Fly   859 GIQTYARGMLARNKFHAMRDHYRAVQIQRFVRGALARRAYQKRR-RNIIICQAAI--RRFLARR- 919

  Fly  1174 NSSQLGPLPVPIKKMPFRLDQIPFYDTQYMVDPANSISRQAFPNQLLTQHMEDDE--PWDSPLQR 1236
                      ..|:|......|...:.:||          ...|::::.....||  ..:|.|:.
  Fly   920 ----------KFKRMKAEAKTISHMENKYM----------GLENKIISMQQRIDELNRDNSNLKH 964

  Fly  1237 NPSMTSCALTYNAYKK---------EQACQTNWDRMGESDNIYNQGYFRDPQQL---RRNQMQMN 1289
            ..|..|........||         :.|||.. |::.|:.|          :||   |..:||:
  Fly   965 KTSEISVLKMKLELKKTLEAEFKNVKAACQDK-DKLIEALN----------KQLEAERDEKMQL- 1017

  Fly  1290 MNAYNNAYNSYNSNYNNQNWGVHRSGSRR--NSLKGYAAPPPPPPPMPSSNYYRNNPNQQQRNYQ 1352
            :....:|...:.|  ..|.|.......||  :.:...|                .|....|||.:
  Fly  1018 LEENGHAQEEWIS--QKQTWRQENEELRRQIDEIIDMA----------------KNAEVNQRNQE 1064

  Fly  1353 QRSSYPPSDPVRELQNMARNEG--------DNSEDPPFNFKAMLRKTNYPRGSETNTYDFNNRRG 1409
            .|.       :.|:.|...||.        :..|:..|..|..|.:..      ..::..:.|:.
  Fly  1065 DRM-------LAEIDNRELNEAYQRAIKDKEVIENENFMLKEELSRLT------AGSFSLHARKA 1116

  Fly  1410 SDSGDQHTFQPPKLRSTGRRYQDDEGYNSSSGNYGVSRKFGQQQRAPTLRQSPASVGRSFEDSNA 1474
            |::..|:              :||.||.|:.....::       |.|.|    .|...|:.||.:
  Fly  1117 SNASSQN--------------EDDVGYASAKNTLDIN-------RPPDL----LSKNYSYNDSTS 1156

  Fly  1475 RSFEEAGSYVEEE 1487
             ...:..|.:|||
  Fly  1157 -LVVKLRSILEEE 1168

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ninaC	NP_523503.2	STKc_myosinIII_N_like	9..282	CDD:270785
		MYSc_Myo21	346..1022	CDD:276848	191/748 (26%)
didum	NP_724569.1	MYSc_Myo5	84..767	CDD:276831	190/736 (26%)
		IQ	900..922	CDD:197470	5/35 (14%)
		SMC_prok_B	<942..1365	CDD:274008	59/296 (20%)
		Myo5_CBD	1424..1792	CDD:271254