Protein Alignment ninaC and Nrk

DIOPT Version :10

• Sequence 1: NP_523503.2
• Gene: ninaC / 34012
• FlyBaseID: FBgn0002938
• Length: 1501
• Species: Drosophila melanogaster
• Sequence 2: XP_063136078.1
• Gene: Nrk / 315907
• RGDID: 1566163
• Length: 1520
• Species: Rattus norvegicus
• Alignment Length: 1628
• Identity: 313/1628 - (19%)
• Similarity: 503/1628 - (30%)
• Gaps: 675/1628 - (41%)

  Fly     9 LPDPTDKFEIYEEIAQGVNAKVFRAKELDNDRIVALKIQH------------------------- 48
            |||||..|.:.:.|..|...:::..........||:|:.:
  Rat    18 LPDPTGIFSLEKTIGLGTYGRIYLGLHEKTGSFVAIKVMNARKTPLPEIGKRVRVNKYRKSVGWR 82

  Fly    49 YDEEHQVSIEEEYRT----LRDYCDHPNLPEFYGV-YKLSKPNGPDEIWFVMEYCAGGTAVDMVN 108
            |.:|     ||:.||    ||.|..|.|:..|||. :||:.|....::|.|||.||.|:..|:|.
  Rat    83 YSDE-----EEDLRTELNLLRKYSFHKNIVTFYGAFFKLNPPGHQHQLWMVMELCAAGSVTDVVR 142

  Fly   109 KLLKLDRRMREEHIAYIIRETCRAAIELNRNHVLHRDIRGDNILLTKNGRVKLCDFGLSRQVDST 173
              :..::.::|:.||||.||..:....|:.:.|:||||:|.|:|||::..||:.|||:|.||..|
  Rat   143 --MTRNQSLKEDWIAYICREILQGLAHLHAHQVIHRDIKGQNVLLTQDAEVKIVDFGVSAQVSRT 205

  Fly   174 LGKRGTCIGSPCWMAPEVVSAMESREPDITVRADVWALGITTIELADGKPPFADMHPTRAMFQII 238
            .|:|.:.||:|.||||||:...|........|:|||::|||.||:|:|.||..::.|..|:|.|:
  Rat   206 NGRRNSFIGTPYWMAPEVIHCDEDPRRSYDYRSDVWSVGITAIEMAEGAPPLCNLQPLEALFVIL 270

  Fly   239 RNPPPTLMRPTNWSQQINDFISESLEKNAENRPMMVEMVEHPFLTELIENEDEMRSDIAEMLELS 303
            |...|| ::.:.||::..:|:...:.||...||....|:.|||:.: |:||             .
  Rat   271 REAAPT-VKSSGWSRKFQNFMENCMIKNFLFRPTSGNMLHHPFVHD-IKNE-------------R 320

  Fly   304 RDVKTLYKEPELFVDRGYVKRFDEKPEKMYPEDLAALENPVDENIIESLRHRILMGESYSFIGDI 368
            |.|::|.|..     .|.:::.:.|                              |...:|.|
  Rat   321 RVVESLTKHL-----TGIIQKRERK------------------------------GIPLAFEG-- 348

  Fly   369 LLSLNSNEIKQEFPQEFHAKYRFKSRSENQPHIFSVADIAYQDMLHHKEPQHIVLSGESYSGKST 433
                      :|...|.:...||:                                     |.|.
  Rat   349 ----------EEAVNEQYITRRFR-------------------------------------GPSC 366

  Fly   434 NARLLIKHLCYLGDGNRGATGRVESSIKAILMLVNAGTPVNNDSTRCVLQYCLTFGKTGKMSGAV 498
            ...||                ||.:                  |:||
  Rat   367 TPELL----------------RVPT------------------SSRC------------------ 379

  Fly   499 FNMYMLEKLRVATTDGTQHNFHIFYYFYDFINQQNQLKEYNLKADRNYRYLRVPPEVPPSKLKYR 563
                  ..|||...:..|..:                               :|.|..|
  Rat   380 ------RPLRVLHGEPPQPRW-------------------------------LPDEEQP------ 401

  Fly   564 RDDPEGNVERYREFENILRDIDFNHKQLETVRK-------------VLAAILNIGNIRFRQNGKY 615
             :|.|  :::.:|...:...:....|.|:.::|             ||..:
  Rat   402 -EDQE--LQQLQEAARMFMPLHSQDKTLKPLQKQAQLPQHLHVAPQVLMPV-------------- 449

  Fly   616 AEVENTDIVSRIAELLRVDEK--KFMWSLTNFIMVKGGIAERRQYTTEEARDARDAVASTLYSRL 678
             :||.| :.:.:|:.:|...:  |..|.||                   :..::|..||:
  Rat   450 -QVEAT-VATPLAKKIRAPPQLSKAAWGLT-------------------SPPSQDNKASS----- 488

  Fly   679 VDFIINRINMNMSFPRAVFGDTNAIIIHDMFGFECFNRNGLEQLMINTLNEQMQYHYNQRIFISE 743
                   ..:....||                                 .:|.|         ::
  Rat   489 -------PEVQAPIPR---------------------------------EQQAQ---------ND 504

  Fly   744 MLEME-AEDIDTINLNFYDNKTALDNLLTKPDGLFYIIDDASRSCQDQDLIMDRVSEKHSQFVKK 807
            .||.| .||:|.:...|.....|.:             :.......:|:...:.|.|:|
  Rat   505 ALETEQPEDLDQVPEEFQGQDRAAE-------------EQRQGQAAEQEQRQNGVPEQH------ 550

  Fly   808 HTATEISVAHYTGRIIYDTRAFTDINRDFVPPEMIETFRSSLDESIMLMFTNQLTKAGNLTMPFE 872
                                  .:.||:   ||..|....:::.                  |..
  Rat   551 ----------------------PEENRE---PEQAEVQEEAVEP------------------PQA 572

  Fly   873 AVQHKDESERKSYALNTLSAGCISQVNNLRTLAANFRFTCLTLLKMLSQN------ANLGVHFVR 931
            .|:.||..              :.||:            ....|.:.|||      .:|....:.
  Rat   573 EVEEKDPE--------------VIQVH------------ARVFLPLQSQNHHVFLPLHLDTQLLI 611

  Fly   932 CIRADLEYKPRSFHSDVVQQQMKALGVLDTVIARQKGFSSRLPFDEFLRRYQFLAFDFDEPVEMT 996
            .:....|..||:...|:  :..:|.|.:..::   :|.|.     :.||          .|...|
  Rat   612 PVGEQNEEAPRAQAWDL--EASRAAGAVQALV---EGLSR-----DLLR----------APNAFT 656

  Fly   997 KDNCRLLFLRLKMEGWALGKTKVFLR------YYNDEFLARLYELQVKKVIKVQSMMRALLAR-- 1053
            ..              .||..::.|.      :|.:.      |...||..:|.|:.:|::.|
  Rat   657 SK--------------PLGPLQILLESLCTNGFYTEP------EAVQKKKSRVSSLKKAIVKRLT 701

  Fly  1054 -KRVKGGKVFKLGKKGPEHHDVAASKIQKAFRGFRDRVRLPPLVNEKSGQLNENTADFIRPFAKK 1117
             ||.:...:::       ..|...|.::.:.|  |.:.|...:.|:...||.|...|      :.
  Rat   702 PKRFRAKALWR-------RQDFECSDVESSRR--RRQRRWEEIFNQHEEQLREVEND------RD 751

  Fly  1118 WREKSIFQVLLHYRAARFQDFVNLSQQVHIYNQRMVAGLNKCTRAVPFERINMREVNSSQLGPLP 1182
            ..:.|....:.|        .:....|:..|...                   |..|..|....|
  Rat   752 DDDSSDNDEVFH--------SIQAEVQIEPYAPN-------------------RTGNEVQERSAP 789

  Fly  1183 VP--------IKKMPFRLDQIPFYDTQYMVD--PANSISRQAFPNQLLTQHMEDDEPWDSPLQRN 1237
            :|        :|..|...:|....:.|..:|  |.||::.:.|..:     .|.....|||:.|.
  Rat   790 MPCNRNRTHRVKFSPSVCEQALLEEAQQPMDIRPRNSLNPRNFQAE-----SESSSEEDSPVTRR 849

  Fly  1238 PSMTS----------------------------CALTYNAYKKEQACQTNWD---------RMGE 1265
            .|.:|                            ..||..........:..||         |..|
  Rat   850 KSQSSPPYSTIDQRLLIDIHVPDGFKVGKISPPVYLTNEWVGCNPLSEVFWDDWVNPTPATRRHE 914

  Fly  1266 SDNIYNQGYFRDPQQLRRNQMQMNMNAYNNAY-NSYNSNYNNQNWGVHRSGSRRNSLKGYAAPPP 1329
            .|..|.:.|..|.....|        |.|.|| .:|.|.:::.|   |:
  Rat   915 EDGDYVELYDADANGDGR--------ASNYAYEENYASGHDDMN---HQ---------------- 952

  Fly  1330 PPPPMPSSNYYRNNPNQQQRNYQQRSSYPPSDPVRELQNMARNEGDNSEDPPFNFKAMLRKTNYP 1394
                   :|.||.:.|   |:|...|              .||.|| |....||..    :.:|.
  Rat   953 -------ANGYRGHGN---RHYSDGS--------------FRNRGD-SRGAAFNGP----RASYC 988

  Fly  1395 RGSETNTYDFNNRRGSDSGDQHTFQPPKLRSTGRRYQDDEGYNSSSGNYGVSRKFGQQQ------ 1453
            ||.      .....|:|..|..       |...|.|.|:|..|......|.|..||.|:
  Rat   989 RGG------ILKNAGNDGRDLR-------RGAFRAYGDNEASNYHGAASGASAAFGSQEGHEGHM 1040

  Fly  1454 ---RAPTLRQSPASVGRS-----------------FED-SNARSFEEAGSYVEEEIAPGITLSGY 1497
               |....|:...|.|.:                 |.| .|.:...:||:...:.||  :.::.:
  Rat  1041 GGRRGNRYREVNGSSGENGACGFHRDGAGLDQQHVFPDFENEQEQSDAGTETSDSIA--LEITSF 1103

  Fly  1498 AVD 1500
            ::|
  Rat  1104 SLD 1106

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ninaC	NP_523503.2	STKc_myosinIII_N_like	9..282	CDD:270785	106/302 (35%)
		MYSc_Myo21	346..1022	CDD:276848	89/697 (13%)
Nrk	XP_063136078.1	None