Protein Alignment ninaC and Myh15

DIOPT Version :10

• Sequence 1: NP_523503.2
• Gene: ninaC / 34012
• FlyBaseID: FBgn0002938
• Length: 1501
• Species: Drosophila melanogaster
• Sequence 2: XP_038944797.1
• Gene: Myh15 / 303965
• RGDID: 1565858
• Length: 1987
• Species: Rattus norvegicus
• Alignment Length: 846
• Identity: 214/846 - (25%)
• Similarity: 386/846 - (45%)
• Gaps: 130/846 - (15%)

  Fly   305 DVKTLYKEPELFVDRG------------YVKRFDEKPEKMYP------EDLAALENPVDENIIES 351
            |.|..|.|.|:....|            .::..:::.::|.|      |||:.|....:.:::.:
  Rat    38 DGKNAYTEAEVKESSGDGHVIVETRDGESLRIREDEIQQMNPAELEMIEDLSMLLYINEGSVLHT 102

  Fly   352 LRHRILMGESYSFIGDILLSLNSNEIKQEFPQEFHAKYRFKSRSENQPHIFSVADIAYQDMLHHK 416
            ||.|......|::.|...:::|..:....:.:|..|.|:.|.|||..||||:||:.|:||||.:.
  Rat   103 LRKRYDHWMIYTYSGLFCVAINPYKWLPVYQKEVMAAYKRKRRSEAPPHIFAVANHAFQDMLRNG 167

  Fly   417 EPQHIVLSGESYSGKSTNARLLIKHLCYLGDGN--RGATGRVESSIKAILMLV----NAGTPVNN 475
            |.|.|:.:|||.|||:.|.:::|::...:...:  :...|.:|..|..:..::    ||.|..|:
  Rat   168 ENQSILFTGESGSGKTVNTKMIIQYFATMAATSEPKKKLGNLEDQIVQMNPILEAFGNAKTLRND 232

  Fly   476 DSTRCVLQYCLTFGKTGKMSGAVFNMYMLEKLRVATTDGTQHNFHIFYYFYDFINQQNQLKEYNL 540
            :|:|......:.||..|.:|.|...:|.|||.||......:.|:||   ||..::.:.:|::..|
  Rat   233 NSSRFGKFIRMYFGVRGTLSFADIQIYFLEKSRVVYQQPGERNYHI---FYQILSGKQELQDMLL 294

  Fly   541 KADRNYRYLRVPPEVPPSKLKY---------RRDDPEG--NVERYREFENILRDIDFNHKQLETV 594
            .:..            ||....         ..||.:|  ..|:..:....|.|..|.      .
  Rat   295 VSTN------------PSDFHICSCGVVAVENLDDAKGFLATEKAIDVLGFLPDEKFG------C 341

  Fly   595 RKVLAAILNIGNIRFRQNGK--YAEVENTDIVSRIAELLRVDEKKFMWSLTNFIMVKGGIAER-- 655
            .|::.||::.||::||||.:  ..|.:.|:...:.|.|:.::..:         ::||.|..|
  Rat   342 YKLVGAIMHFGNLKFRQNPREEQLEADGTENADKAALLMGINASE---------LLKGLIYPRIK 397

  Fly   656 --RQYTT-----EEARDARDAVASTLYSRLVDFIINRINMNMSFPRAVFGDTNAIIIHDMFGFEC 713
              .:|.|     ::...|..|::.::|.|:..:::.|:|..:.   |.......|.|.|:.|||.
  Rat   398 VGNEYVTRSQNIQQVTYAVGALSKSIYERMFKWLVARMNQVLD---AKVTSHFFIGILDITGFEI 459

  Fly   714 FNRNGLEQLMINTLNEQMQYHYNQRIFISEMLEMEAEDIDTINLNFYDNKTALDNLLTKPDGLFY 778
            .:.|.||||.||..||::|..:||::|:.|..|...|.:|.:::::..:..|..:|:.||.|:..
  Rat   460 LDYNSLEQLCINFTNEKLQQFFNQQLFVLEQEECRKEGLDWMSIDYGLDLQACIDLIEKPMGILS 524

  Fly   779 IIDDASRSCQ----DQDLIMDRVSEKH---SQFVKKHTATE------ISVAHYTGRIIYDTRAFT 830
            |:::   .|.    ..:....::...|   |.:.:|.||.|      ..:|||.|.:.||...:.
  Rat   525 ILEE---ECMLPKATDNTFKTKLFAHHFGKSAYFQKPTAPEKNFEVHFELAHYAGVVPYDISGWI 586

  Fly   831 DINRDFVPPEMIETFRSSLDESIMLMFTNQLTKAGNLTMPFEAVQHKDESERKSYALNTLSAGCI 895
            ..|::.:...::...:.|.::.:..:|||. |.||:..:  ::::..::..||:.:...:::...
  Rat   587 GKNKELLNETVVALLQKSSNKVLASLFTNN-TIAGSGEL--DSIEFGEKPRRKATSFQLITSLHK 648

  Fly   896 SQVNNLRTLAANFRFTCLTLLKMLSQNANLGVHFVRCIRADLEYKPRSFHSDVVQQQMKALGVLD 960
            ..:|                 |:::...:...||||||..:....|.......|.||::..|||:
  Rat   649 ESIN-----------------KLMADLKSTAPHFVRCINPNENKIPGVMDPFWVLQQLRCNGVLE 696

  Fly   961 TVIARQKGFSSRLPFDEFLRRYQFL---AFDFDEPVEMTKDNCRLL-FLRLKMEGWALGKTKVFL 1021
            ......|.|..|:.:|:|.:||..|   .|...:.|.:.|....:| .|.:....:..|.||||
  Rat   697 GTRVCCKAFPIRMLYDDFKQRYCILNPRIFSKSKFVNIRKATEEVLALLEIDQSQYQCGVTKVF- 760

  Fly  1022 RYYNDEFLARLYELQVKKVIKVQSMMRALLARKRVKGGKVFKLG-KKGPEHHDVAASKIQKAFRG 1085
              :....|.||.|.:.:|:.||.::.:   ||.|   ||:.::. :|..|..| |.:.||:..|.
  Rat   761 --FKARILDRLEERRDEKISKVFTLFQ---ARAR---GKLMRITFQKILEERD-ALALIQENIRA 816

  Fly  1086 F 1086
            |
  Rat   817 F 817

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ninaC	NP_523503.2	STKc_myosinIII_N_like	9..282	CDD:270785
		MYSc_Myo21	346..1022	CDD:276848	182/720 (25%)
Myh15	XP_038944797.1	Myosin_N	29..74	CDD:460670	6/35 (17%)
		Motor_domain	98..762	CDD:473979	182/722 (25%)
		Myosin_tail_1	843..1919	CDD:460256