Protein Alignment ninaC and Myo9b

DIOPT Version :10

• Sequence 1: NP_523503.2
• Gene: ninaC / 34012
• FlyBaseID: FBgn0002938
• Length: 1501
• Species: Drosophila melanogaster
• Sequence 2: XP_063131141.1
• Gene: Myo9b / 25486
• RGDID: 3146
• Length: 2151
• Species: Rattus norvegicus
• Alignment Length: 1364
• Identity: 308/1364 - (22%)
• Similarity: 540/1364 - (39%)
• Gaps: 332/1364 - (24%)

  Fly   244 TLMRPTNWSQQINDFISESLEKNAENRPMMVEMVE------------HPFLTELI----ENEDEM 292
            |..:.:..|..|.|.:: ||..:.....::||:.|            .|....|:    ..::..
  Rat    37 TATKDSTTSDVIRDVVA-SLHLDGSKHYVLVEVKESGGEEWVLDASDSPVHRVLLWPRRAQKEHP 100

  Fly   293 RSDIAEML--ELSRDVKTLYKEPEL---------FVDRGYVKRFDEKPEKMYPEDLAALENPVDE 346
            |.|....|  |.:.|....|...:|         .|:||.:.|    |:..: :||..|....:.
  Rat   101 REDGYYFLLQERNADGSIQYLHVQLLAQPTAACRLVERGLLPR----PQADF-DDLCNLPELNEA 160

  Fly   347 NIIESLRHRILMGESYSFIGDILLSLNSNEIKQEFPQEFHAKYRFKSRSENQPHIFSVADIAYQD 411
            |:::||:.|.:..:.|::.|.||:::|..:....:..::...|..:...:.:||:|::||:||..
  Rat   161 NLLQSLKLRFVQQKIYTYAGSILVAINPFKFLPIYNPKYVKMYENQQLGKLEPHVFALADVAYYT 225

  Fly   412 MLHHKEPQHIVLSGESYSGKSTNARLLIKHLCYLGDGNRGATGRVESSI----KAILMLVNAGTP 472
            ||.....|.||:||||.|||:.:...||.  |......:|....||.:|    ..:....||.|.
  Rat   226 MLRKHVNQCIVISGESGSGKTQSTNFLIH--CLTALSQKGYASGVERTILGAGPVLEAFGNAKTA 288

  Fly   473 VNNDSTRCVLQYCLTFGK--------TGKMSGAVFNMYMLEKLRVATTDGTQHNFHIFYYFYDFI 529
            .||:|:|        |||        :|.:.|||...|:|||.|:.:.:..:.|:|:|||....:
  Rat   289 HNNNSSR--------FGKFIQVNYLESGIVRGAVVEKYLLEKSRLVSQEKDERNYHVFYYLLLGV 345

  Fly   530 NQQNQLKEYNLKADRNYRYLRVPPEVPPSKLKYRRDDPEGNVERYREFENILRDIDFNHKQLETV 594
            :::.: :|:.||..::|.||        ::.....:|.|.....:...:..:..:.|.....:.:
  Rat   346 SEEER-QEFQLKQPQDYFYL--------NQHNLNIEDGEDLKHDFERLQQAMEMVGFLPATKKQI 401

  Fly   595 RKVLAAILNIGNIRFRQNG----KYAEVENTDIVSRIAELLRVDEKKFMWSLTNFIMVKGGIAER 655
            ..||:|||.:||:.:::..    :..||...:::..:::||:|..:..:..||....:.......
  Rat   402 FSVLSAILYLGNVTYKKRATGRDEGLEVGPPEVLDTLSQLLKVKRETLVEVLTKRKTITVNDKLI 466

  Fly   656 RQYTTEEARDARDAVASTLYSRLVDFIINRINMNM----SFPRAVFGDTNAIIIHDMFGFECFNR 716
            ..|:..||..|||::|.:|||.|.|:|:.|||..:    ....||  ...:|.:.|:||||.|.|
  Rat   467 LPYSLSEAITARDSMAKSLYSALFDWIVLRINHALLNKKDMEEAV--SCLSIGVLDIFGFEDFER 529

  Fly   717 NGLEQLMINTLNEQMQYHYNQRIFISEMLEMEAEDIDTINLNFYDNKTALDNLLTKPDGLFYIID 781
            |..||..||..|||:||::.|.||..|..|.:.|.|...|:::.||...:..:..||.||||::|
  Rat   530 NSFEQFCINYANEQLQYYFTQHIFKLEQEEYQGEGISWHNIDYTDNVGCIHLISKKPTGLFYLLD 594

  Fly   782 DASR-SCQDQDLIMDRVSEKHSQFVKKHTATEI-----SVAHYTGRIIYDTRAFTDINRDFVPPE 840
            :.|. .......::.:..::|.. .|....|.:     .:.|:.||:.|..:.|.:.|.|::.|:
  Rat   595 EESNFPHATSHTLLAKFKQQHED-NKYFLGTPVLEPAFIIQHFAGRVKYQIKDFREKNMDYMRPD 658

  Fly   841 MIETFRSS--------------------------------------------------------- 848
            ::...|.|
  Rat   659 IVALLRGSDSSYVRQLIGMDPVAVFRWAVLRAAIRAMAVLREAGRLRAERAEKAEAGVSSPVTRS 723

  Fly   849 -------------------------------LD----ESIMLMFT------NQLTKA--GNLTMP 870
                                           ||    |.||..:.      ||:.|:  |   :|
  Rat   724 HVEELPRGANTPSEKLYRCAGLDFSFERSEELDVNAFEDIMAFYESRNDLHNQIIKSLKG---LP 785

  Fly   871 FEA--------------------VQHKDESERKSYALNTLSAG----CISQVNNLRT-------- 903
            ::.                    ::.|...:::....|.|.:.    .||...:.||
  Rat   786 WQGEDPRRLLQSLSRLQKPRTFFLKSKGIKQKQIIPKNLLDSKSLRLIISMTLHDRTTKSLLHLH 850

  Fly   904 -------LAANFRFTCLTLLKMLSQNANLGVHFVRCIRADLEYKPRSFHSDVVQQQMKALGVLDT 961
                   ::|.|:   .:|.|:|.........|:||||::.|.|...|..::|.||::..|:|:|
  Rat   851 KKKKPPSISAQFQ---TSLNKLLEALGKAEPFFIRCIRSNAEKKELCFDDELVLQQLRYTGMLET 912

  Fly   962 VIARQKGFSSRLPFDEFLRRYQFLAFDFDEPVEMTKD--NCR------LLFLRLKMEGWALGKTK 1018
            |..|:.|:|::..|.:|..::|.|         :.||  .||      |..|::..:.:.:||||
  Rat   913 VRIRRSGYSAKYTFQDFTEQFQVL---------LPKDVQPCREAIAALLEKLQVDRQNYQIGKTK 968

  Fly  1019 VFLRYYNDEFL-ARLYELQVKKVIKVQSMMRALLARKRVKGGKVFKLGKKGPEHHDV----AASK 1078
            |||:....:.| .||:...:::::.:||..|.:|.|:                 |.|    ||..
  Rat   969 VFLKETERQALQERLHGEVLRRILLLQSWFRMVLERR-----------------HFVQMKHAALT 1016

  Fly  1079 IQKAFRGFRDRVRLPPLVNEKSGQLNENTADFIRPFAKKWREKSIFQVLLHYRAA--RFQDFVNL 1141
            ||..:|.:|.|..|     |::     ..|.:::   ..||.....|...|.|.:  |.|.....
  Rat  1017 IQACWRSYRVRRTL-----ERT-----RAAVYLQ---AAWRGYLQRQAYHHQRHSIIRLQSLCRG 1068

  Fly  1142 SQQVHIYNQRMVAGLNKCTRAVPFERINMREVNSSQLG---PLPVPIKKMPFRLDQIPFYDTQYM 1203
            ..|...::|.|:. ..|..:|        ||...:::.   |.||...:.|   .:.|..|.:.:
  Rat  1069 HLQRRSFSQMMLE-KQKAEQA--------RETAGAEMSEGEPSPVAAGEQP---SEHPVEDPESL 1121

  Fly  1204 VDPANSISRQAFPNQLLTQHMEDDEPWDSPLQRN-PSMTSCALTYNAYKKEQACQTNWDRMGESD 1267
            .....:......||.|..:........::|.|:. |:.:...:..:..|:|...|...:.: |..
  Rat  1122 GVETETWMNSKSPNGLSPKKEIPSPEMETPAQKTVPAESHEKVPSSREKRESRRQRGLEHV-ERQ 1185

  Fly  1268 NIYNQGYFRDPQQLRRNQMQMNMNAYNNAYNSYNSNYNNQNWGVHRSGSRRNSLKGY---AAPPP 1329
            |.:.|....:...||....:.::.             ..:::.......|.:.|:.:   |||..
  Rat  1186 NKHIQSCREENSTLREPSRKASLE-------------TGESFPEDTKEPREDGLETWTETAAPSC 1237

  Fly  1330 P--------PPPMPSSNYYRNNPNQQQRNYQQRSSYPPSDPVRELQN-MARNEGDNS---EDPP 1381
            |        ||..||       |.|:..:....|...|..|...|:: ...::|:||   :|.|
  Rat  1238 PKQVPIVGDPPRSPS-------PLQRPASLDLDSRVSPVLPSSSLESPQDEDKGENSTKVQDKP 1294

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ninaC	NP_523503.2	STKc_myosinIII_N_like	9..282	CDD:270785	10/49 (20%)
		MYSc_Myo21	346..1022	CDD:276848	206/848 (24%)
Myo9b	XP_063131141.1	None