DRSC/TRiP Functional Genomics Resources

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Protein Alignment ninaC and NRK

DIOPT Version :9

Sequence 1:NP_523503.2 Gene:ninaC / 34012 FlyBaseID:FBgn0002938 Length:1501 Species:Drosophila melanogaster
Sequence 2:NP_940867.2 Gene:NRK / 203447 HGNCID:25391 Length:1582 Species:Homo sapiens


Alignment Length:348 Identity:117/348 - (33%)
Similarity:186/348 - (53%) Gaps:35/348 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly     9 LPDPTDKFEIYEEIAQGVNAKVFRAKELDNDRIVALKIQHYDE-------------EHQVSI--- 57
            |||||..|.:.:.|..|...:::...........|:|:.:..:             ::|.|:   
Human    18 LPDPTGIFSLDKTIGLGTYGRIYLGLHEKTGAFTAVKVMNARKTPLPEIGRRVRVNKYQKSVGWR 82

  Fly    58 ----EEEYRT----LRDYCDHPNLPEFYGV-YKLSKPNGPDEIWFVMEYCAGGTAVDMVNKLLKL 113
                ||:.||    ||.|..|.|:..|||. :|||.|....::|.|||.||.|:..|:|.  :..
Human    83 YSDEEEDLRTELNLLRKYSFHKNIVSFYGAFFKLSPPGQRHQLWMVMELCAAGSVTDVVR--MTS 145

  Fly   114 DRRMREEHIAYIIRETCRAAIELNRNHVLHRDIRGDNILLTKNGRVKLCDFGLSRQVDSTLGKRG 178
            ::.::|:.||||.||..:....|:.:.|:||||:|.|:|||.|..|||.|||:|.||..|.|:|.
Human   146 NQSLKEDWIAYICREILQGLAHLHAHRVIHRDIKGQNVLLTHNAEVKLVDFGVSAQVSRTNGRRN 210

  Fly   179 TCIGSPCWMAPEVVSAMESREPDITVRADVWALGITTIELADGKPPFADMHPTRAMFQIIRNPPP 243
            :.||:|.||||||:...|........|:|||::|||.||:|:|.||..::.|..|:|.|:|...|
Human   211 SFIGTPYWMAPEVIDCDEDPRRSYDYRSDVWSVGITAIEMAEGAPPLCNLQPLEALFVILRESAP 275

  Fly   244 TLMRPTNWSQQINDFISESLEKNAENRPMMVEMVEHPFLTELIENEDEMRSDIAEML------EL 302
            | ::.:.||::.::|:.:...||...||....|::|||:.: |:||..:...:...|      ..
Human   276 T-VKSSGWSRKFHNFMEKCTIKNFLFRPTSANMLQHPFVRD-IKNERHVVESLTRHLTGIIKKRQ 338

  Fly   303 SRDVKTLYKEPELFVDRGYVKRF 325
            .:.:..:::..|...::..|:||
Human   339 KKGIPLIFEREEAIKEQYTVRRF 361

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ninaCNP_523503.2 STKc_myosinIII_N_like 9..282 CDD:270785 108/297 (36%)
S_TKc 16..282 CDD:214567 103/290 (36%)
MYSc 327..1034 CDD:214580
MYSc_Myo21 346..1022 CDD:276848
NRKNP_940867.2 PKc_like 18..313 CDD:304357 108/297 (36%)
S_TKc 25..313 CDD:214567 103/290 (36%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 492..579
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 783..859
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 926..1156
CNH 1213..1549 CDD:295303
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0587
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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