Protein Alignment ninaC and nmy-1

DIOPT Version :10

• Sequence 1: NP_523503.2
• Gene: ninaC / 34012
• FlyBaseID: FBgn0002938
• Length: 1501
• Species: Drosophila melanogaster
• Sequence 2: NP_508504.2
• Gene: nmy-1 / 180581
• WormBaseID: WBGene00003776
• Length: 1963
• Species: Caenorhabditis elegans
• Alignment Length: 1127
• Identity: 268/1127 - (23%)
• Similarity: 484/1127 - (42%)
• Gaps: 244/1127 - (21%)

  Fly   242 PPTLMRPTNWSQQINDFISESLEKNAENRPMMVEMVEHPFLTELIENEDEMRSDIAEMLELSRDV 306
            |.||   ..|:|:...::.:      :|...::..::.       |..||:   :.|:::.||.|
 Worm    17 PATL---AAWAQRKLCWVPD------QNEGFLIGSIKR-------ETNDEV---LVELVDTSRQV 62

  Fly   307 KTLYKEPELFVDRGYVKRFDEKPEKMYPEDLAALENPVDENIIESLRHRILMGESYSFIGDILLS 371
             |:.::.   |.:....:||:      .||::.|....:.:::.:|:.|......|::.|...:.
 Worm    63 -TISRDD---VQKANPPKFDK------IEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVV 117

  Fly   372 LNSNEIKQEFPQEFHAKYRFKSRSENQPHIFSVADIAYQDMLHHKEPQHIVLSGESYSGKSTNAR 436
            :|..:....:.::...:::.|.|.|..||||::||.||:.||..:|.|.|:.:|||.:||:.|.:
 Worm   118 INPYKKLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTK 182

  Fly   437 LLIKHLCYLGDGNRGAT-------------------GRVESSIKAILMLV----NAGTPVNNDST 478
            .:|::|.::....|..:                   |.:|..:.....::    |:.|..|::|:
 Worm   183 KVIQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSS 247

  Fly   479 RCVLQYCLTFGKTGKMSGAVFNMYMLEKLRVATTDGTQHNFHIFYYFYDFINQQNQLKEYNLKAD 543
            |......:.|..:|.:|||....|:|||.||......:.:|||||......:.:.: .||.|:..
 Worm   248 RFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEK-SEYLLEGV 311

  Fly   544 RNYRYLRVPPEVPPSKLKYRRDDPEGNVERYREFE---NILRDIDFNHKQLETVRKVLAAILNIG 605
            .|||:|            ..|.....||:..:||.   |.:|.:.|...::.::.:|::|:|.:|
 Worm   312 DNYRFL------------VNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLG 364

  Fly   606 NIRFRQNGK--YAEVENTDIVSRIAELLRVD----EKKFMWSLTNFIMVKGGIAERRQYTTEEAR 664
            |:.|.|..|  .|.:::..::.::..||.:.    :|.|   |...|.|......:.| ..|:|.
 Worm   365 NLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAF---LRPRIKVGREFVNKAQ-NQEQAE 425

  Fly   665 DARDAVASTLYSRLVDFIINRINMNMSFPRAVFGDTNAIIIHDMFGFECFNRNGLEQLMINTLNE 729
            .|.:|:|...|.||..:::.||  |.|..|......:.|.|.|:.|||.|:.|..||:.||..||
 Worm   426 FAVEAIAKASYERLFKWLVTRI--NKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNE 488

  Fly   730 QMQYHYNQRIFISEMLEMEAEDIDTINLNF-YDNKTALDNLLTKPDGLFYIIDDASRSC-----Q 788
            ::|..:|..:||.|..|.:.|.|:...::| .|.:..:| |:.||.|:..::|:   .|     .
 Worm   489 KLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTID-LIEKPMGVLALLDE---ECLFPKAN 549

  Fly   789 DQDLI--MDRVSEKHSQFV------KKHTATEISVAHYTGRIIYDTRAFTDINRDFVPPEMIETF 845
            |:..:  :.:...||.:|:      |.|.|    |.||.||:.|....:...|.|
 Worm   550 DKSFVEKLQKTHNKHPKFIVPDMRSKSHFA----VVHYAGRVDYSADQWLMKNMD---------- 600

  Fly   846 RSSLDESIMLMFTNQLTKAGNLTMPFEAVQHKDESERKSYALNTLSAG-CISQVN----NLRTLA 905
              .|:|:::.:..|.       |.||.|...||..          .|| |.:::|    .:|:..
 Worm   601 --PLNENVVGLMQNS-------TDPFVAGIWKDAE----------FAGICAAEMNETAFGMRSRK 646

  Fly   906 ANFRFTCL----TLLKMLSQNANLGVHFVRCIRADLEYKPRSFHSDVVQQQMKALGVLDTVIARQ 966
            ..||....    .|.|:::...|...||||||..:.|.|....:|::|.:|::..|||:.:...:
 Worm   647 GMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICR 711

  Fly   967 KGFSSRLPFDEFLRRYQFLAFD-----FDEPVEMTKDNCRLLFLRLKMEG--WALGKTKVFLRYY 1024
            :||.:|:||.||..||:.|..|     |.:    .|::.|.:...|.::.  :.:|::|||.|
 Worm   712 QGFPNRVPFQEFRHRYEILTPDVIPKNFID----GKESVRKMITALDIDTNLYRIGQSKVFFR-- 770

  Fly  1025 NDEFLARLYELQVKK----VIKVQSMMRALLAR----KRVKGGKVFKLGKKGPEHHDVAASKIQK 1081
             ...||.|.|.:..|    ::..|:..|..|:|    :|.:.....::    .:.:.:|..|::.
 Worm   771 -TGVLAHLEEERDLKLTALIMNFQAQCRGFLSRRLYTRRQQQSSAIRI----IQRNGLAYLKLRN 830

  Fly  1082 AFRGFRDRVRLPPL---------VNEKSGQLNENTADFIRPFAKKWR--EKSIFQVLLHYRAARF 1135
             ::.:|...::.||         :..|..:|.. |.:.:......:|  ||.:.||::.
 Worm   831 -WQWWRLFTKVKPLLQVTRTDDEIRAKDDELRA-TKERLLKMEHDFRENEKKLDQVIVE------ 887

  Fly  1136 QDFVNLSQQVHIYNQRMVAGLNKCTRAVPFERINMREVNSSQLGPLPVPIKKMPFRLDQIPFYDT 1200
                                     |||..|::.....||::|..:...:        |....:.
 Worm   888 -------------------------RAVIQEQLQQESENSAELDDIRGRL--------QTRNQEL 919

  Fly  1201 QYMV-DPANSISRQAFPNQLLTQHMEDDEPWDSPLQRNPSMTSCALTYNAYKKEQACQ------T 1258
            :|:| |..:.:|.:...|:     ..:||      :|....|...|.....::|||.|      |
 Worm   920 EYIVNDMRDRLSEEEQQNE-----KNNDE------RRKQMETVRDLEEQLEQEEQARQKLLLDKT 973

  Fly  1259 NWD--------RMGESDNIYNQ 1272
            |.|        |:.|..:.|::
 Worm   974 NVDQRLRNLEERLVELQDAYDK 995

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ninaC	NP_523503.2	STKc_myosinIII_N_like	9..282	CDD:270785	6/39 (15%)
		MYSc_Myo21	346..1022	CDD:276848	196/737 (27%)
nmy-1	NP_508504.2	Myosin_N	26..69	CDD:460670	9/62 (15%)
		MYSc_class_II	92..770	CDD:276951	196/737 (27%)
		Myosin_tail_1	847..1919	CDD:460256	36/200 (18%)